Gene Information

Name : zobellia_4276 (zobellia_4276)
Accession : YP_004738690.1
Strain : Zobellia galactanivorans DsiJT
Genome accession: NC_015844
Putative virulence/resistance : Resistance
Product : Macrolide-specific ABC transporter ATPase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 4992764 - 4993507 bp
Length : 744 bp
Strand : +
Note : This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); ly involved in the macrolides resistance; Localiz

DNA sequence : 
ATGAGCAAAGAGATCATTAAAATACAAGATTTAAAACGCGACTTTACCATGGGCACTGAAACGGTCCATGCGCTACGGGG
TATCTCGTTCGCCATTAATGAAGGCGAGTTCGTGACGATTATGGGATCGAGTGGTTCTGGAAAAAGTACCTTACTGAATA
TTTTGGGCTGTTTGGACCAACCTACATCGGGCACGTATGAAATTGACGGGCTAAAAGTAAAGGATCTGAGCCGAAACGAG
TTGGCTACCATCCGCAACGAGAAAATCGGTTTTATTTTTCAATCGTACAACCTGTTGGCACGTACTTCGGCCATTGAGAA
CGTAGAACTTCCCCTTTTGTACAATAGCAAGGTCTCTACCGAAGAACGTCGTGAACGTGCCATAAAGGCATTGGAAATGG
TAGGTTTGGCCGACCGCCTGCACCATACACCTTCACAGCTTTCGGGCGGTCAGCAGCAGCGTGTGGCCATTGCCCGTTCA
TTGGTGAACAATCCGGTAATGATCCTGGCCGATGAGGCTACGGGAAATTTGGACACCCGCACATCTTACGAGATCATGTC
GCTTTTTCAAGAACTGAACAAGCAGGGCATCACCATCACCTTTGTTACCCACGAACCCGATATTGCCACCTTTAGTAGTA
GAACTATCGTATTGAAAGATGGTAATATCATTCAAGATTACTTGAACGACAACATACAATCGGCAGCAGAAGAATTAGCA
AAATTACCTAAAGAAGACCATTGA

Protein sequence : 
MSKEIIKIQDLKRDFTMGTETVHALRGISFAINEGEFVTIMGSSGSGKSTLLNILGCLDQPTSGTYEIDGLKVKDLSRNE
LATIRNEKIGFIFQSYNLLARTSAIENVELPLLYNSKVSTEERRERAIKALEMVGLADRLHHTPSQLSGGQQQRVAIARS
LVNNPVMILADEATGNLDTRTSYEIMSLFQELNKQGITITFVTHEPDIATFSSRTIVLKDGNIIQDYLNDNIQSAAEELA
KLPKEDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-33 43
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-35 43
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 5e-35 43
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-35 43
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 3e-29 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
zobellia_4276 YP_004738690.1 Macrolide-specific ABC transporter ATPase NC_012469.1.7686878. Protein 7e-56 53
zobellia_4276 YP_004738690.1 Macrolide-specific ABC transporter ATPase NC_008702.1.4606598. Protein 5e-45 46
zobellia_4276 YP_004738690.1 Macrolide-specific ABC transporter ATPase CP001581.1.gene798.p Protein 1e-36 44
zobellia_4276 YP_004738690.1 Macrolide-specific ABC transporter ATPase CP001581.1.gene598.p Protein 1e-39 43