Gene Information

Name : metC (zobellia_4001)
Accession : YP_004738417.1
Strain : Zobellia galactanivorans DsiJT
Genome accession: NC_015844
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4710375 - 4711550 bp
Length : 1176 bp
Strand : +
Note : Cystathionine beta-lyase (CBL) is found in the Selenoamino acids metabolism pathway and in methionine and cysteine biosynthesis pathways. It converts (seleno)cystathionine to (seleno)homocysteine but is also able to catalyze an alpha, gamma elimination; U

DNA sequence :
ATGCAGCAGAAGAAAATAGGCCTCAATACGATATGTACCCATGTGGGCGAGGTGAAAGATGAACAGTTTAAAGGAGCGGT
TTCCCCACTTTATATGAGTAGTTCGTATGCCTTTGAAGACGTTGATGTAAAACGATATCCCAGATATTTCAACACTCCCA
ACCAAGAGGCCCTGTGCAAGAAAATAGCGGCTTTGGAGCATACCCAAGCCGGTCTGATATTCGGTAGTGGCATGGCGGCC
ATTACTACCTCCTTAATGGCATTTTTAAGGGCAGGGGACCACGTGGTACTCCAGCAAGTGTTGTACGGAGGTACTTATAA
TTTAGTGGTGGAGGAATTCGATAAATTTGGTATCGAATATTCCTTTACCCATGGATGGGCCCCTGAAGACTTCGAGAAAA
AGATCCGATCGAATACCAAGGTGATATATATAGAAACGCCTTCCAATCCACTTTTGACCATAACCGATTTGGATGCCATC
GGGAAGTTGGCCAAAAAACACGGACTCATCTCTATGATCGATAATACTTTCGCAAGTCCGGTAAACCAAAACCCTATAGA
CTTCGGTATTGACGTGGTCATTCATAGTGCTACAAAGTATATGGGAGGCCATTCGGATATTTTGGCGGGAGCAGTGGCTT
CCTCCGAAGAAAATATCAATCGAATTTTCGCTTTGGCGAAGAACTTTGGCGGAAGCCTTAGTGATTATACGGTCTGGCTG
CTCGAAAGAAGCTTGAAGACCATGGGATTGCGTGTAAAGGCCCAAAACGCCAACGCCCAGCATATGGCCGAATACCTGTT
CGGGCACAAAGCGGTTACCCGGGTCTATTACCCAGGCTTAAAGAGCCATCCCGATCACGAATTGGCCAAATCGCAAATGA
ACGGTTTTGGGGGCATGCTGTCCTTTGAATTACATGAAGATTACGATGCTACCCAGTTTCAAAAAGAACTACAATTGATA
AAGCCTTCCATGAGTTTGGCAGGTGTAGAGAGCACCATGCTTTCGCCAACCAAGACCTCTCATGCCCTTTTGGGGGCCGA
AGAAAGGGCAAAACAAGGTATCTTAGATGGTTTGATCCGTTTTTCGGTAGGAATAGAAGAGCCCGAAGATTTAATTGCCG
ATATCGAACAGGCCTTGGAAAAAGTAAGGTTGGGCAGGGTAGCAACGACTAGTTAG

Protein sequence :
MQQKKIGLNTICTHVGEVKDEQFKGAVSPLYMSSSYAFEDVDVKRYPRYFNTPNQEALCKKIAALEHTQAGLIFGSGMAA
ITTSLMAFLRAGDHVVLQQVLYGGTYNLVVEEFDKFGIEYSFTHGWAPEDFEKKIRSNTKVIYIETPSNPLLTITDLDAI
GKLAKKHGLISMIDNTFASPVNQNPIDFGIDVVIHSATKYMGGHSDILAGAVASSEENINRIFALAKNFGGSLSDYTVWL
LERSLKTMGLRVKAQNANAQHMAEYLFGHKAVTRVYYPGLKSHPDHELAKSQMNGFGGMLSFELHEDYDATQFQKELQLI
KPSMSLAGVESTMLSPTKTSHALLGAEERAKQGILDGLIRFSVGIEEPEDLIADIEQALEKVRLGRVATTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-61 42
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-62 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-63 41