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Name : vipA (zobellia_3771) Accession : YP_004738188.1 Strain : Zobellia galactanivorans DsiJT Genome accession: NC_015844 Putative virulence/resistance : Virulence Product : Vi polysaccharide biosynthesis protein vipA Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG0677 EC number : 1.1.1.- Position : 4425849 - 4427129 bp Length : 1281 bp Strand : - Note : VipA is involved in the biosynthesis of an exopolysaccharide. In Salmonella typhi, this EPS is the Vi antigen. VipA belongs to the UDP-glucose/GDP-mannose dehydrogenase, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2- DNA sequence : ATGAAAAATATTAAAATAGCAATAATAGGATTGGGTTATGTTGGCCTACCTCTTGCACGATTATTTGCTACGAAGTATCC GGTAATCGGATTTGACATCAACGAGGAACGGATTAAAGAATTGCAATCCGGCACGGACAGTACCTTAGAGGTAGAAGACG ATATTTTGCAACAAGTGTTGCGCGATACCCCTCAAATGGAAACCGGGCTACATTGTACGAACCAAATGGAGGCAATTTCC GATTGCAACTATTACATCGTAACCGTCCCCACTCCTGTGGACCACACCAACAGACCTGTTCTAACGCCTTTGTACAAATC AAGCGAAACGGTTGGGAAGGTGTTGAAAAAAGGAGACACCGTCGTCTATGAATCCACGGTATACCCTGGCGTAACGGAAG AAGAGTGTATCCCTGTACTCGAAAAAGTAAGTGGACTCGTCTTTAACAAAGATTTCTTTGTTGGATATTCCCCTGAACGT ATCAATCCAGGTGACAAGGAACATACCGTAGAAAAGATTCTAAAGGTTACTTCGGGCTCTACTCCGGAAACCGGAAAAAA AGTCAATGCCCTATATGCTTCGGTAATCACTGCCGGCACCCACCTTGCCCCCTCCATAAAGGTAGCAGAGGCCGCCAAGG TAATTGAAAACTCTCAAAGGGATATCAATATCGCCTTTGTAAACGAATTGGCAAAAATCTTCAATTTAATGGATATTGAC ACGAGTGCCGTACTTGAGGCAGCGGGGACCAAATGGAACTTCTTGCCCTTCAAACCCGGACTGGTTGGTGGCCATTGTAT TGGTGTTGACCCCTATTATCTCGCCCAAAAAGCACAAGAGTTCGGTTATCACCCCGAAATCATCCTAGCCGGTAGGCGTA TGAATGATGGTATGGGGAAATACGTAGCTTCTGAAGTTATCAAATTAATGGTTCAACGGGAGATAAAGATAAAAGGAGCC AAAATGCTCGTTTTAGGTATTACCTTTAAAGAAAATTGTCCCGATGTACGAAACACTAAGGCGGTAGACGTAATTACCAA CCTTAAGAGCTACGGGGCCAATATCAGTATCTTCGACCCATGGGCCTCCAAGGAAGAAGTTGAAGAAGAATATGGCCTAG AAATAGTAAACCAAGTACCTAACGAAAAGTACGATACCATTGTTCTTGCCGTTGCCCATAATGAGTTTTTAAATATTGAC CTACGAGCCCTTTTAAACGAAAACGGTGTGTTATACGATGTAAAAGGCATCTTAAAAGGTAAGGTAGACGGTAGACTTTA A Protein sequence : MKNIKIAIIGLGYVGLPLARLFATKYPVIGFDINEERIKELQSGTDSTLEVEDDILQQVLRDTPQMETGLHCTNQMEAIS DCNYYIVTVPTPVDHTNRPVLTPLYKSSETVGKVLKKGDTVVYESTVYPGVTEEECIPVLEKVSGLVFNKDFFVGYSPER INPGDKEHTVEKILKVTSGSTPETGKKVNALYASVITAGTHLAPSIKVAEAAKVIENSQRDINIAFVNELAKIFNLMDID TSAVLEAAGTKWNFLPFKPGLVGGHCIGVDPYYLAQKAQEFGYHPEIILAGRRMNDGMGKYVASEVIKLMVQREIKIKGA KMLVLGITFKENCPDVRNTKAVDVITNLKSYGANISIFDPWASKEEVEEEYGLEIVNQVPNEKYDTIVLAVAHNEFLNID LRALLNENGVLYDVKGILKGKVDGRL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tviB | NP_458740.1 | Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase | Virulence | SPI-7 | Protein | 4e-114 | 56 |
| tviB | NP_807945.1 | VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase | Virulence | SPI-7 | Protein | 4e-114 | 56 |
| cap1L | AAA64651.1 | type 1 capsule synthesis gene | Virulence | SCCcap1 | Protein | 1e-107 | 56 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| vipA | YP_004738188.1 | Vi polysaccharide biosynthesis protein vipA | VFG0431 | Protein | 2e-114 | 56 |
