Gene Information

Name : thiC (zobellia_3654)
Accession : YP_004738071.1
Strain : Zobellia galactanivorans DsiJT
Genome accession: NC_015844
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein thiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4285275 - 4287134 bp
Length : 1860 bp
Strand : +
Note : ThiC is involved in thiamine biosynthesis, but its precise catalytic function is still unknown. It is required for the synthesis of the hydromethylpyrimidine moiety of thiamine (4-amino-2-methyl-5- hydroxymethylpyrimidine). Localized in the cytoplasm.; Hi

DNA sequence :
ATGAAAAAAAGAGACACCGCCCCAAAAGAAGGTCAAATTACAAGACATCCCTTTCCGAATTCGAAAAAAATCTATGTAAG
TGGAAAGATCCACCCAGAGCTTAAAGTGGCCATGCGTGAGATTACTTTGAGCGATACCAAAGATTCCCTCACGGGTAAGC
TAACCCCTAACGAACCTGTAACGGTATACGATACGTCGGGACCCTACACAGATCCCGAAAAGGAAATAAACGTACACAAT
GGTATAGAACGCATACGCGAACCGTGGATATTAGATCGTGGTGATGTGGAACGACTGGAGGGCTTCTCTTCTGAATACTG
TAACCAACGCTTGAAGGATCCAAGCCTTGACCATATGCGTTTTTCACACCTGAAAACACCCCTACGGGCGAAAAAGGGTA
AAAACGTAACCCAGTTGCACTACGCCAAACAGGGTATAATTACTCCTGAAATGGAATACATCGCCATCCGTGAAAACCAA
AGGATCGATGAGATGACGGAGATTGCCAAGCAGCACAAGGGCGAACATTTTGGAGCGGCTATTCCCCAAAAAATAACACC
GGAATTTGTTCGTGATGAAGTGGCCCGGGGGCGTGCGGTTATTCCTTCCAATATAAACCACCCAGAAGCGGAACCTATGA
TCTTGGGCCGTAACTTTTTGGTAAAGATCAATGCGAATATCGGTAACTCGGCTACGACCTCTTCCATTGAAGAGGAAGTG
GAAAAAGCGGTTTGGGCCTGTCGTTGGGGAGCCGACAATATAATGGACCTCTCTACCGGTCAAAATATTCACGAAACCCG
GGAATGGATCATCCGTAATTCCCCGGTTCCCGTAGGTACCGTACCGATCTACCAAGCACTCGAAAAGGTAAACGGTGTTG
CCGAAGATCTTACTTGGGAAATTTTTAGGGATACCTTAATCGAGCAGGCTGAACAGGGAGTGGACTACTTTACGATCCAT
GCGGGCGTTTTGTTACGTTACGTTCCTATGACGGCCAAACGGGTTACCGGTATCGTTTCCCGTGGCGGTTCCATCATGGC
GAAGTGGTGTTTGGCGCATCATAAAGAGAGTTTCCTGTACACCCATTTTGAAGATATCTGCGAAATCCTGAAGCAATACG
ATGTGGCCTTTTCATTGGGTGACGGACTACGACCGGGTTCGGTGGCCGATGCCAATGACGAAGCCCAATTTGCCGAGTTG
GAGACCTTGGGCGAATTGACAAAAATTGCCAGAAAGCACGAAGTACAATGTTTTATCGAAGGTCCAGGTCACGTGCCCAT
GCATATGATCAAGGAGAATATGGAAAGGCAAATAGAGGTTTGCGACGAAGCCCCGTTTTACACCTTGGGCCCGTTAACGA
CCGATATCGCCCCTGGTTATGACCATATAACCTCAGGAATCGGTGCGGCCATGATCGGTTGGTACGGATGCGCCATGTTG
TGCTATGTCACACCAAAGGAACATTTGGGCTTACCGAATAAAGATGATGTACGAACTGGGGTAGTTACCTATAAATTGGC
GGCCCATGCGGCAGATCTGGCAAAAGGACATCCTGGGGCACAACATCGTGATAATGCCTTGAGCAAAGCGCGATTCGAAT
TCCGTTGGGAAGATCAGTTCAACTTGGGCTTGGATCCAGAGCTGGCCCGTGAGTACCATGATGAGACCTTGCCTGCGGAT
GGAGCCAAGATTGCACATTTCTGCTCTATGTGCGGCCCTAAATTTTGTTCCATGAAAATATCTCAGGAAGTACGTGATTT
TGCCGCTGCCAATGATATCGTAGATAACGAAGTCATTCAGAAAGGTATGGAAGAAAAATCAAAAGAGTTTAAGGATAAGG
GCTCGGAAGTGTATTTGTAA

Protein sequence :
MKKRDTAPKEGQITRHPFPNSKKIYVSGKIHPELKVAMREITLSDTKDSLTGKLTPNEPVTVYDTSGPYTDPEKEINVHN
GIERIREPWILDRGDVERLEGFSSEYCNQRLKDPSLDHMRFSHLKTPLRAKKGKNVTQLHYAKQGIITPEMEYIAIRENQ
RIDEMTEIAKQHKGEHFGAAIPQKITPEFVRDEVARGRAVIPSNINHPEAEPMILGRNFLVKINANIGNSATTSSIEEEV
EKAVWACRWGADNIMDLSTGQNIHETREWIIRNSPVPVGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIH
AGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEILKQYDVAFSLGDGLRPGSVADANDEAQFAEL
ETLGELTKIARKHEVQCFIEGPGHVPMHMIKENMERQIEVCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAML
CYVTPKEHLGLPNKDDVRTGVVTYKLAAHAADLAKGHPGAQHRDNALSKARFEFRWEDQFNLGLDPELAREYHDETLPAD
GAKIAHFCSMCGPKFCSMKISQEVRDFAAANDIVDNEVIQKGMEEKSKEFKDKGSEVYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 71
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 71
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 69