Gene Information

Name : zobellia_2757 (zobellia_2757)
Accession : YP_004737186.1
Strain : Zobellia galactanivorans DsiJT
Genome accession: NC_015844
Putative virulence/resistance : Virulence
Product : NAD dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3227410 - 3228930 bp
Length : 1521 bp
Strand : -
Note : Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These

DNA sequence :
ATGAGCACACAAACAGTTGAACACAATCTTCTTCAAAAGCCAAAGTTCAAAGACCAATATGAAAATTATATTGGCGGAAA
ATGGACAGCACCAGTAAAAGGCGAGTATTTTGACAACCTTTCGCCTGTTGACGGCAAGGTATACACCAAAGTAGCACGCT
CTACTTCGGAAGATATTGAATTGGCCATCGATGCCGCATGGAAAGCCGCCCCCGAATGGAACACTTCTTCGGCCACTACA
AGAAGTAATATGCTATTAAAGATTGCCGACGTCATGGAGCGCAACCTTGAAGCCCTTGCAAGAGCGGAAACCTGGGACAA
CGGTAAAGCTATTCGTGAAACCACTGCAGCCGATATTCCTTTGGCCATAGATCACTTCCGTTATTTTGCAGGTGTCATCC
GTGCCGAAGAAGGTTCGGTAAGCGAATTAGATTCGAACACCGTAGCCCTGAACGTTACGGAACCCCTAGGTGTGGTAGGA
CAGATTATCCCATGGAACTTCCCCCTACTTATGGCTACCTGGAAGTTGGCCCCGGCCTTGGCGGCAGGTAACTGTGTTGT
TTTGAAACCTGCGGAACAGACCCCTGCAGGAATCATGATCTTAATGGAACTTATTGACGGCATCCTTCCCGCGGGTGTAT
TGAACGTAGTGAACGGTTTTGGGGCCGAAGCAGGGAAACCCTTGGCCTCAAGCCCAAGAATAAGCAAAATTGCATTCACC
GGAGAGACCACTACAGGCCAGCTCATAATGCAGTACGCCTCTAAAAACATCACGCCCGTTACCTTGGAACTTGGAGGGAA
ATCACCTAACATTTTCTTTGAAAGCATTATCGATGCCGATGACGATTTCTTCGACAAATGTTTGGAAGGTGCGGTAATGT
TCGCATTGAACCAAGGGGAAGTATGTACCTGCCCCTCTAGAATGTTAGTACAAGAAAGCATTTACGACCGCTTTATGGAA
AGGGTCATCGAACGTACCAAGGCCATTAAACTAGGGCACCCCTTAGACCCAACGACCATGATGGGGGCACAGGCCTCAAA
CGACCAGTACGAAAAAATATTGAACTATATCAATATAGGCAAAGACGAGGGCTGCGAGGTATTGACCGGTGGCGAAGCCG
CATATAACGAAGGCCTTGAGGGCGGCTATTACATTCAACCTACCATTCTCAAGGGCAACAACAAGATGCGGGTGTTTCAA
GAGGAAATTTTCGGACCCGTTGTTTGTGTCACCACTTTTAAAGATGAAGCAGAGGCCATAGAAATTGCCAATGACACCTT
ATACGGCCTTGGCGCGGGAGTCTGGACACGTGACACCCATCAGGCCTATCAAATATCAAGGGCGGTGCAAGCCGGACGCG
TATGGGTCAATTGCTACCACTTGTATCCTGCACACGCTCCTTTTGGCGGATACAAAAAATCGGGTATCGGTAGGGAAAAC
CACAAAATGATGTTGGCCCACTACAGACAGACCAAGAACATGTTGATTTCATACGACAAAAAGGCCATGGGCTTCTTTTA
A

Protein sequence :
MSTQTVEHNLLQKPKFKDQYENYIGGKWTAPVKGEYFDNLSPVDGKVYTKVARSTSEDIELAIDAAWKAAPEWNTSSATT
RSNMLLKIADVMERNLEALARAETWDNGKAIRETTAADIPLAIDHFRYFAGVIRAEEGSVSELDSNTVALNVTEPLGVVG
QIIPWNFPLLMATWKLAPALAAGNCVVLKPAEQTPAGIMILMELIDGILPAGVLNVVNGFGAEAGKPLASSPRISKIAFT
GETTTGQLIMQYASKNITPVTLELGGKSPNIFFESIIDADDDFFDKCLEGAVMFALNQGEVCTCPSRMLVQESIYDRFME
RVIERTKAIKLGHPLDPTTMMGAQASNDQYEKILNYINIGKDEGCEVLTGGEAAYNEGLEGGYYIQPTILKGNNKMRVFQ
EEIFGPVVCVTTFKDEAEAIEIANDTLYGLGAGVWTRDTHQAYQISRAVQAGRVWVNCYHLYPAHAPFGGYKKSGIGREN
HKMMLAHYRQTKNMLISYDKKAMGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-152 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-158 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-158 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-158 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-157 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
zobellia_2757 YP_004737186.1 NAD dependent aldehyde dehydrogenase VFG0082 Protein 3e-152 63