Gene Information

Name : pyk (SALIVB_1191)
Accession : YP_004727997.1
Strain : Streptococcus salivarius CCHSS3
Genome accession: NC_015760
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1285244 - 1286746 bp
Length : 1503 bp
Strand : -
Note : -

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACACTTGGTCCTGCGGTTGAAATCCGTGGCGGCAAAAAATTTGGTGAAGATGG
TTACTGGGGTGAAAAACTTGACCGTGAAGCATCTGCTAAAAACATTGCTCAATTGATCAAGGAAGGTGCTAACGTTTTCC
GTTTCAACTTCTCACATGGTGACCACGCTGAACAAGGTGAACGTATGGATGTCGTTCGTATGGCAGAAGACCTTGCTGGT
CAAAAAGTAGGTTTCCTTCTTGATACAAAAGGACCTGAAATCCGTACTGAATTGTTCGAAGGTGATGCTAAAGAGTATGC
ATACAAAACTGGTGAACAAATTCGTGTTGCTACTAAACAAGGTATCAAATCAACTCGCGACGTTATCGCATTGAACGTTG
CAGGTGCACTTGACGTTTTTGACGATGTAGAAGTTGGTAAACAAGTTCTTGTCGATGATGGTAAACTTGGTCTTCGTGTT
GTAGACAAAGATGCTGAAAAACGTGAATTCATCGTTGAAGTTGAAAATGATGGTATCATCGCTAAACAAAAAGGTGTAAA
CATCCCTTACACTAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAACGCTGATATCCGTTTTGGTCTTGAACAAGGTC
TTAACTTTATCGCTATCTCATTCGTACGTACTGCAAAAGACGTACAAGAAGTTCGTGCTATCTGTGAAGAAACTGGTAAC
GGTCACGTTCAATTGTTGGCTAAAATCGAAAACCAACAAGGTATCGATAACATCGATGAAATCATCGAAGCTGCTGACGG
TATCATGATCGCTCGTGGTGACATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATCATCACAA
AAGTTAACGCTGCTGGTAAAGTTGTTGTTACAGCTACAAACATGCTTGAAACAATGACAGAAAAACCACGTGCAACTCGT
TCTGAAGTATCTGACGTATTCAACGCAGTTATCGATGGTACAGATGCTACAATGCTTTCTGGTGAGTCTGCAAATGGTAA
ATACCCAGTTGAATCAGTTCGTACAATGGCTACAATTGATAAAAACGCTCAAACTCTTCTTAAAGAGTATGGTCGTCTTG
ATTCATCAACATTTGACCGTTCAACTAAGACTGAAGTAGTTGCGTCTGCAGTTAAAGATGCTACTAACTCAATGGATATC
AAACTTGTTGTTGCTCTTACTGAATCAGGTAACACTGCTCGTTTGATTTCTAAATACCGTCCAGAAGCTGATATCTTGGC
TGTAACATTCGATGAAATTACTCAAAAATCATTGATGCTTAACTGGGGTGTTATTCCAGTAGTTACTGAAAAACCAAGCT
CAACTGATGACATGTTTGATGTTGCTGAAAAAGTTGCATTGGAATCAGGTCTTGTAGAATCTGGTGACAACATTGTTATC
GTTGCTGGTGTTCCTGTAGGTACAGGTGGTACAAACACTATGCGTATCCGCACAGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDREASAKNIAQLIKEGANVFRFNFSHGDHAEQGERMDVVRMAEDLAG
QKVGFLLDTKGPEIRTELFEGDAKEYAYKTGEQIRVATKQGIKSTRDVIALNVAGALDVFDDVEVGKQVLVDDGKLGLRV
VDKDAEKREFIVEVENDGIIAKQKGVNIPYTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVQEVRAICEETGN
GHVQLLAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKVVVTATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDKNAQTLLKEYGRLDSSTFDRSTKTEVVASAVKDATNSMDI
KLVVALTESGNTARLISKYRPEADILAVTFDEITQKSLMLNWGVIPVVTEKPSSTDDMFDVAEKVALESGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-73 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-73 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-73 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-73 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004727997.1 pyruvate kinase VFG0479 Protein 7e-74 43