Gene Information

Name : clpC (SALIVB_0106)
Accession : YP_004726965.1
Strain : Streptococcus salivarius CCHSS3
Genome accession: NC_015760
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 88816 - 91245 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTTGGAGACTTGGCATGTGCTTCT
CGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACCGTATTCGTGCGGAAGAGATTG
AGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATTATCGATTTACGTGCACAGTCA
CATGCTTTAGAGGTTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGTAGAGGTAGGGTCTGAACATGT
ATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTGGTTTTCAATATAAGGATGACA
GCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGTAAGCAAGATTTGAAGGCCATT
CATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCAGCCTCCTCAATCTTCTACTGG
GGAACTGTCAGATTATACCAAAGACTTAACGGCAGTAGCCGAATTAGATGCTCTTGATCCTGTTATTGGACGTGAGAAAG
AAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTGGGTGAAGCAGGTGTTGGTAAG
ACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTTGGCTGATATGCGTATCTTAGA
GCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTATGAATCAGATCATTGATGAGA
TTGAAGCTGATGGAAAAATCATTCTTTTTATTGACGAATTGCATACGATTATTGGTTCTGGTTCAGGTATTGATAGCACC
TTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACTCTTCATATGGTTGGAGCAACTACTCAAGCTGAGTA
CCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTGAGGAGCCAAGTGTACCTGAGG
CGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATTACTGATGAGGCGGTTGAGACA
GCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGATCTTTTAGATGAAGCGAGTGC
AACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAGCGCTTCTATCTGGTGATATGA
AGGCTGCTGTTAAACAATATAAAGCTAGCCAAAAAGCAAAATTACCAGAACCTGCCTTGGTAGATGCAGATCAGATTATG
CAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAAGCGTTACTTGAATCTGGAAGC
AGAGCTTCATAAACGTGTTATTGGTCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTATTCGTCGTAACCAGTCAGGTA
TTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGTAAGACAGAGTTGGCCAAGGCT
TTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATACATGGAAAAATTTGCGGCTAG
CCGCCTTAATGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAGAGAAAGTTCGCAATAAGCCTT
ACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTCTTACAGGTTTTGGATGATGGT
GTCTTGACGGATAGTCGAGGTCGTAAAGTCGATTTCTCAAATACCATTATCATTATGACTTCGAACTTGGGAGCGACTGC
TCTTCGTGATGATAAGACTATTGGATTTGGTGCCCAAGACATTTCTCATAATCACCAAGCAATGCAGTCACGTATCATGG
AAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTCTTCCATAGTCTAGAGGAAGAG
CAACTTCGTGAGATTGTCAAGATTATGATGAAACCGTTGGTATCAGCTTTGGCTGAAAAAGGGATTGACTTGAAATTCCA
ACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTCCATTACGTCGCACGATTCAAA
CTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGTCAAGTAGTTAGTGGACAAACTCTTAAAATCGGCTGCTCG
AAAGATAAATTAACCTTTACAGTAGTGTAA

Protein sequence :
MQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDIIDLRAQS
HALEVMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLSKQDLKAI
HDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAELDALDPVIGREKEISRMIQVLSRKTKNNPVLVGEAGVGK
TALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGSGSGIDST
LDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVPEAIDILKGLRSSYEDYHRVTITDEAVET
AVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPEPALVDADQIM
QTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQVLDDG
VLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTIGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVVFHSLEEE
QLREIVKIMMKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQTLKIGCS
KDKLTFTVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-152 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004726965.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 1e-170 54
clpC YP_004726965.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 1e-136 45