Gene Information

Name : CTL2C_380 (CTL2C_380)
Accession : YP_004717626.1
Strain : Chlamydia trachomatis L2c
Genome accession: NC_015744
Putative virulence/resistance : Virulence
Product : type 4 fimbriae expression regulatory protein pilR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 860688 - 861848 bp
Length : 1161 bp
Strand : +
Note : [KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism

DNA sequence :
ATGTCGATAGAACACATTCTTATTATTGACGATGATCCCCATATCCTGGCTCTTCTTTCTGAGATACTGGGCGCTCGGAA
CTTTTCAGTGTCTTCTGCTCCAGGAGTCAAACAAGCTATTAAGCAGATCTCTAACTGTCCTTTCGATCTGATTATTTCCG
ATATGAATATGCCTGATGGTTCAGGATTGGATATTATCCAGTATACAAAACAGCATCGTCCGCAAACCCCTATCTTGGTC
ATTACTGCTTTCGGAACTATTCAAAATGCTGTTGAAGCTATGCGATTCGGAGCTTTTAACTATCTGACCAAACCGTTTTC
CCCCGATGCCCTTTTTACTTTAATCGCTAAAGCCGAAGAACTCCAAGCGCTACAACAAGACAACCTATTTCTACAATCAC
AAGGATCCTCCATCTCACATCCTCTGATCGCCGAAAGTCCTTCCATGAAACAGCTACTTGATAAAGCTCGCCGAGCGGCT
AACAGTTCTGCGAATATATTCGTACACGGAGAATCCGGATGCGGAAAAGAAAATCTTTCATTTTTTATCCACAAGCACTC
CCCTCGATCTACTAAGCCCTATATTAAAGTCAATTGTGCTGCTATCCCCGATACTTTGTTAGAATCTGAGTTTTTCGGGC
ACGAAAAAGGAGCTTTCACAGGAGCAACCACGAAGAAAGTAGGAAGATTTGAACTCGCCCACCAAGGCACTCTTTTACTA
GATGAAATCACAGAAATTCCGATCCATTTGCAAGCCAAACTTTTGCGGGCAATACAAGAACAAGAATTCGAACATATTGG
AGGAATAAAAACCCTCCCTGTAAACATTCGATTTCTAGCCACTTCCAATCGTGACCTTGAGGAAGCTATTGAAACCAAAG
TTCTCCGTCAAGATCTCTACTATCGATTGAGTGTGATCTCTTTACACATCCCTCCCCTTCGCGATAGAAAAGAAGATATC
CTCCCTTTAGCTCATTACTACTTAGAAAAATTTTGTAAGATGAATAATAAGCCTCCAAAAACATTGTCTTTAGAAGCGCA
AAGAAATCTTTTGGACTATTCATGGCCTGGGAATGTTCGAGAACTCTCTAACGTACTCGAACGAACTGTTATTCTAGAAA
ACGATCCTGCGATCACTCCTTCTATGCTCGCTCTCTTATAA

Protein sequence :
MSIEHILIIDDDPHILALLSEILGARNFSVSSAPGVKQAIKQISNCPFDLIISDMNMPDGSGLDIIQYTKQHRPQTPILV
ITAFGTIQNAVEAMRFGAFNYLTKPFSPDALFTLIAKAEELQALQQDNLFLQSQGSSISHPLIAESPSMKQLLDKARRAA
NSSANIFVHGESGCGKENLSFFIHKHSPRSTKPYIKVNCAAIPDTLLESEFFGHEKGAFTGATTKKVGRFELAHQGTLLL
DEITEIPIHLQAKLLRAIQEQEFEHIGGIKTLPVNIRFLATSNRDLEEAIETKVLRQDLYYRLSVISLHIPPLRDRKEDI
LPLAHYYLEKFCKMNNKPPKTLSLEAQRNLLDYSWPGNVRELSNVLERTVILENDPAITPSMLALL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 6e-61 42
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 6e-61 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTL2C_380 YP_004717626.1 type 4 fimbriae expression regulatory protein pilR VFG1249 Protein 4e-74 45
CTL2C_380 YP_004717626.1 type 4 fimbriae expression regulatory protein pilR VFG1214 Protein 7e-75 44
CTL2C_380 YP_004717626.1 type 4 fimbriae expression regulatory protein pilR VFG0116 Protein 1e-65 42