Gene Information

Name : CTL2C_948 (CTL2C_948)
Accession : YP_004717427.1
Strain : Chlamydia trachomatis L2c
Genome accession: NC_015744
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 636139 - 638703 bp
Length : 2565 bp
Strand : +
Note : [O] COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTTGAGAAGTTTACCAATCGCGCAAAGCAAGTGATTAAGTTGGCGAAAAAAGAGGCTCAACGACTCAATCACAACTA
TCTAGGAACCGAGCACATCTTGTTAGGATTACTAAAATTAGGCCAGGGTGTGGCTGTTAATGTATTACGCACTCTTGGTG
TTGACTTCGATACAGCAAAGCACGAAGTAGAAAGGCTGATTGGCTATGGCCCCGAGATTCAAGTTTACGGAGATCCAGCT
CTTACTGGAAGAGTGAAGAAATCTTTTGAATCCGCTAATGAAGAAGCTGCTCTTTTAGAACACAATTATGTTGGAACTGA
ACATCTTTTGTTAGGTATTCTCAATCAATCCGATGGAGTGGCTTTGCAAGTATTAGAAAATTTGCACGTGGATCCTAAAG
AAATCCGAAAAGAGATTTTAAAAGAATTAGAAACATTTAATTTACAACTCCCCCCCTCTTCCTCCATCACTCCTAGAAAT
ACTAATAGCTCTTCTTCTTCGAAATCTTCTTCTCCTTTAGGAGGTCATACTTTGGGCGGAGATAAACCTGAAAAACTTTC
AGCTTTGAAGGCGTACGGTTACGACTTAACAGAAATGTTTAAAGAATCGCGCCTCGATCCAGTGATCGGGCGTTCTGCAG
AAGTCGAACGATTAATTTTAATTCTTTGTCGTCGAAGAAAAAATAACCCAGTCTTAGTTGGAGAAGCTGGAGTAGGGAAA
ACAGCCATTGTAGAAGGCCTCGCTCAGAAAATTGTCTCAGGAGAAGTTCCTGAAGCTCTTCGTAAAAAACGCTTGATCAC
TTTAGATTTGGCTCTAATGATTGCAGGAACCAAATACAGAGGGCAGTTTGAAGAACGCATCAAAGCTGTGATGGATGAAG
TTCGTAAACATGGGAACATCCTCTTATTTATTGATGAGCTTCACACGATTGTTGGTGCAGGAGCTGCTGAAGGAGCTATC
GATGCTTCTCATATTCTAAAACCAGCTCTAGCTCGAGGAGAAATTCAGTGCATTGGCGCTACGACCCTAGATGAATACCG
TAAACATATAGAAAAAGATGCCGCTTTAGAACGTCGGTTCCAAAAAATCGTTGTTCAACCTCCTAGCGTCGATGAAACAG
TAGAAATTCTCAGAGGTTTAAAGAAAAAATACGAAGAGCATCACAATGTCTTCATCACTGATGAAGCACTCGTTGCTGCA
GCTAAACTCTCTGACCAATATGTTCATGGTCGATTTCTTCCTGATAAAGCAATTGACCTCTTGGATGAAGCTGGAGCTCG
TGTACGAGTCAATACGATGGGACAACCTTCGGACCTGATGCGTCTAGAAGCTGAGATAGAAAAAACAAAACAAGCTAAAG
AGCAAGCTATCGGAACTCAGGAATACGAAAAAGCTGCTAGCCTTCGTGATGAAGAGAAGAAGTTAAGAGAAAAATTAGGA
AATATGAAACAACAGTGGGAGTCCAATAAGGAAGAACATCAAGTTCCCGTTGATGAAGAAGCTGTTGCACAAGTAGTTTC
CGTACAAACAGGAATTCCTGCAGCTCGTTTAACAGAAGCTGAAAGCGAAAAACTTTTAACCTTAGAAACGACTCTACAAA
AGAAAGTAATCGGCCAAAGTCAAGCTGTTGCTAGTATCTGTAGAGCTATCCGTCGTTCTAGAACAGGCATCAAAGATCCT
AATAGACCTATGGGATCCTTCCTATTTTTGGGCCCAACTGGTGTCGGGAAGACTTTATTAGCGCAGCAAATCGCAATTGA
GATGTTTGGAGGAGAAGATTCTCTTATTCAAGTGGACATGTCTGAGTACATGGAAAAATTTGCAGCCACTAAGATGATGG
GATCTCCTCCAGGATATGTCGGTCATGAGGAAGGGGGTCATCTAACAGAGCAAGTCCGTCGCCGCCCTTACTGTGTTGTG
TTGTTTGATGAAATTGAAAAAGCACATCCAGATATTATGGACCTTATGCTTCAGATTTTGGAGCAAGGGCGTTTAACAGA
CTCATTTGGACGTAAGATCGATTTTCGTAATACCATCATCATTATGACTTCTAACCTAGGAGCAGATTTAATTCGGAAAA
GTGGTGAAATAGGGTTTGGGCTTCGTTCTCACATGGACTATGCAGTTATCAAAGAGAAAATAGATGCTGCAGTTAAGAAG
CATTTAAAACCTGAGTTTATCAACCGTTTAGATGAGAGTGTTATCTTTAAGCCTCTTGAAAAAGAAGCTCTTTCAGAGAT
TATCCATCTAGAGATTAATAAGCTGGGCTCTCGTTTACAAAACTATCAAATGGATCTTAATATTCCTGATTCAGTGATTT
CCTTTTTGGTAACTAAAGGGCATTCGCCAGAAATGGGAGCTCGACCTTTAAGACGTGTTGTGGAGCAGTATCTGGAGGAT
CCTTTGGCAGAAATGCTATTGAAAGAGTCTTGCCGACAAGAAGCTAGAAAATTACGCGCGCGCCTCACAGAAGAACGCGT
TGTTTTCGAAAGAGAAGAAGAAGCTGTTTCTGCTTTAGCTATAGAAGGCGATGGCTCAGAGCCTATTACAGCTGATGAAT
CATAG

Protein sequence :
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKHEVERLIGYGPEIQVYGDPA
LTGRVKKSFESANEEAALLEHNYVGTEHLLLGILNQSDGVALQVLENLHVDPKEIRKEILKELETFNLQLPPSSSITPRN
TNSSSSSKSSSPLGGHTLGGDKPEKLSALKAYGYDLTEMFKESRLDPVIGRSAEVERLILILCRRRKNNPVLVGEAGVGK
TAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAI
DASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKYEEHHNVFITDEALVAA
AKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSDLMRLEAEIEKTKQAKEQAIGTQEYEKAASLRDEEKKLREKLG
NMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLTLETTLQKKVIGQSQAVASICRAIRRSRTGIKDP
NRPMGSFLFLGPTGVGKTLLAQQIAIEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVV
LFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKSGEIGFGLRSHMDYAVIKEKIDAAVKK
HLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNYQMDLNIPDSVISFLVTKGHSPEMGARPLRRVVEQYLED
PLAEMLLKESCRQEARKLRARLTEERVVFEREEEAVSALAIEGDGSEPITADES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 8e-170 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTL2C_948 YP_004717427.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 51
CTL2C_948 YP_004717427.1 negative regulator of genetic competence clpC/mecB VFG0080 Protein 7e-141 50