Gene Information

Name : Spica_2702 (Spica_2702)
Accession : YP_004699307.1
Strain : Treponema caldaria DSM 7334
Genome accession: NC_015732
Putative virulence/resistance : Unknown
Product : site-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 3055786 - 3057339 bp
Length : 1554 bp
Strand : -
Note : -

DNA sequence :
ATGGCAAGAAAAAATATCAAAAAACCAAACCCTTCCAACTCCAACGAAAATATAGAGGACATGCTCTGGAAATCGGCGGA
CAAGCTCCGGAAAAACATTGACGCCGCTGAGTATAAGCATGTGGTACTGGGGCTCATCTTTCTAAAATATATTTCAGATT
CCTTTGAGGAGCTCCATGCGAAACTTGAGGCCGAGATCGCTAATGGTGCCGACCCGGAAGACCGGGACGAATACAGAGCA
GAAAATGTCTTTTTTGTCCCCGAAACAGCCCGCTGGTCATACCTGGTGTCCAAGGCAAAGGATCCGGAAATCGGCAAGTA
TGTTGATGAAGCTATGGACGCCCTTGAAAAAGAAAATGCCTCCCTTAAGGGAGTGCTTCCCAAGGTGTATGCCCGGGGTA
ACCTGGACCCCACCAGTCTGGGCGGACTACTCGACCTCATCGGGAACATTGCCCTCGGCGAAGCTAAAGAGCGCAGTGCT
GACCTTTTGGGCCATGTGTTTGAGTATTTCCTGGGAGAATTTGCCCTGGCAGAAGGCAAAAAGGGCGGCCAATTCTACAC
CCCTAAAAGCGTTGTGGAACTCCTTGTGGAAATGCTGGAACCCTATAAAGGCCGGGTCTTTGACCCCTGCTGTGGCTCCG
GCGGCATGTTTGTGCAGTCGGAAAAATTTGTCATGGCCCACCAAGGGAACATCAACGACATTTCCATTTACGGCCAGGAA
AGCAATCAGACAACCTGGCGGCTCTGTAAAATGAACCTGGCCATTCGCGGCATTGACAGTTCCCAGGTGAAATGGAACAA
CGAAGGCTCTTTTTTAAACGACGCCCATAAAGACCTTAAGGCCGACTTTGTTATAGCAAACCCACCCTTTAATGATAGCG
ACTGGGCGGGCGAACTTCTGCGGAACGACGGACGGTGGAAATTCGGCATACCCCCGGCAAGTAACGCCAACTACGCCTGG
ATACAGCACTTTCTCTATCATTTGAATCCCACGGGTGTCGCCGGTTTTGTGCTGGCTAAAGGTTCGCTCACTTCCAAAAG
CTCCGGCGAAGGTGAAATCCGTAAGGCATTAGTTGAAGCAAGGCTAGTTGACTGTATCGTCAATCTTCCGGCAAAACTCT
TTTTAAATACCCAAATTCCCGCCTGCCTCTGGTTCCTCTCCCGCAACAAAGCCAATGGCGGTTACCGAAACCGCACCGAC
GAGATTCTGTTCATCGACGCCCGCAACGAAGGGGTGCTCATCAATCGCCGCACCAGAATACTGCGGGAAGAAGATATCCA
GAAAATTGCCCAAACCTACCACGAATGGCGCAAAGTTAACGGAAACTATCAAGATGTTAAGGGCTTCTGCAATTCCGCTA
CCGTTGAGCGTGTTAAAGAGCTTGATTATGTCCTTACCCCGGGCAGGTATGTAGGACTTCCCGATGATGAAGACGATTTT
GATTTTGCGGAACGGTTTACTCAGCTCAAGGCCGAGTTCGAGGCACAGCTCAAAGAGGAAGCCGAATTGAATAAGGCCAT
ACTGGATAATCTTAAGAAGGTTAAGCTCGTATGA

Protein sequence :
MARKNIKKPNPSNSNENIEDMLWKSADKLRKNIDAAEYKHVVLGLIFLKYISDSFEELHAKLEAEIANGADPEDRDEYRA
ENVFFVPETARWSYLVSKAKDPEIGKYVDEAMDALEKENASLKGVLPKVYARGNLDPTSLGGLLDLIGNIALGEAKERSA
DLLGHVFEYFLGEFALAEGKKGGQFYTPKSVVELLVEMLEPYKGRVFDPCCGSGGMFVQSEKFVMAHQGNINDISIYGQE
SNQTTWRLCKMNLAIRGIDSSQVKWNNEGSFLNDAHKDLKADFVIANPPFNDSDWAGELLRNDGRWKFGIPPASNANYAW
IQHFLYHLNPTGVAGFVLAKGSLTSKSSGEGEIRKALVEARLVDCIVNLPAKLFLNTQIPACLWFLSRNKANGGYRNRTD
EILFIDARNEGVLINRRTRILREEDIQKIAQTYHEWRKVNGNYQDVKGFCNSATVERVKELDYVLTPGRYVGLPDDEDDF
DFAERFTQLKAEFEAQLKEEAELNKAILDNLKKVKLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-136 57
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-136 57
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-135 56
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 5e-109 46