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Name : Spica_2695 (Spica_2695) Accession : YP_004699300.1 Strain : Treponema caldaria DSM 7334 Genome accession: NC_015732 Putative virulence/resistance : Unknown Product : type I site-specific deoxyribonuclease, HsdR family Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 3050639 - 3053860 bp Length : 3222 bp Strand : - Note : - DNA sequence : ATGCCGCACCATAACCTTACCGAATCCGCCATCGAAGACCTTGCCATCAAGTTGTTCAAGTCCCTGGGGTATCATCACCT CTACGGTCCTGATAGTGCGCCGGAAGGGAAACATCCCGAGCGGAGCTCTTTCGAGGATGTGATTCTTGTAAATCGGCTCC GGGATGCGGTTAAAAAGATTAACCCTCACATACCCCAACAGTCCCTGGATGATGCGATACGGCAGGTTCTGCGGTTTCCA TCGCAGGAGCTTATTGCTAATAACCAAAGCTTTCACCGCCTCCTTACCGAGGGTGTTAAGATTAGTTACCATAAAGATGG CAGCGAGCGGGGAGACCTGGTGTGGCTCATCGATTTTAAGCATCCTGAAAATAATGAATTTGTCGTGGTGAACCAGTTTG CGGTAATAGAAAACCATCAGAATAAGCGGCCCGATGTGGTGCTGTTTGTGAACGGACTCCCCCTCGTAGTCATCGAGCTA AAAAATGCGGCGGACGAAAATGCCACCATCCAATCGGCCTATAACCAGATTCAGACCTACAAGCAGGCCATACCTGGTTT TTTTACTTACAATGAAATTATCGTTATTTCCGATGGGCTCGAAGCCCGATCTGGCAGTCTTTCCGCAGGGCTTGACCGTT TTGTTGCGTGGAAATCGGTGGATGGCCGCATAGAAGCATCGAGCCTCGAAAGCCAGCTGACAACCCTTATTAAGGGCATG CTGACCCCCCTGACACTCATCGATATAATCCGCCATTTTATCGTCTATGAAGCTTCTAAACACGAGGATCCGGAGACAGG GCTTACTGTGATTCGCACCGTAAAGAAAATAGCGGCCTATCATCAATATTATGCGGTGAATCGGGCGGTGGCCTCCACCA TCAGGGCTGCAGGATACGAGCAGGCCGCCCAACTGCCGGTTGCCGCCCCATGGCCTGCATCGCTTAAGGAGGACCCCGAA GCCTATGGTCTTCCGAGTGTTCGGGAACAGCCGGTGCACGATAAAAAGGCAGGGGTTATTTGGCACACCCAGGGAAGCGG AAAATCTCTTTCCATGGTGTTCTACACGGGAAAGGTGGTGCTCACCCTGGATAATCCCACGGTGGTGGTGATTACCGACC GGAACGATCTGGATGACCAGCTTTTTACTACCTTTGCCGCTTCCAAACAGCTTTTGCGGCAGGAGCCGGTTCAGGCGGAA AGCCGGGACCACTTAAAACAGCTCCTGCGGGTCGCTTCCGGAGGCATCGTATTTACCACGATACAAAAGTTCCAGCCCGA TGAGGGGAATGTGTACGACGTGCTCTCTAACCGGAACAACATCATCGTGATTGTCGATGAGGCCCATCGAACCCAGTATG GTTTTCAGGCAAAGGTTGATGCGAATACCGGCGCTATTACCTATGGCTTTGCCAAATACCTCAGGGATGCGCTGCCCAAT GCGACCTATATCGGTTTTACCGGCACGCCGATAGAAAAAACGGACCGGAATACCCCCGCTGTGTTTGGCAACTATATCGA TATTTATGATATTGCTCAGGCTGTTGCCGATGGAACCACGGTACGAATCTTTTACGAAAGCCGCCTTGCAAAAATTGCTC TGAGCGATGAGGGGAAAAAGCTCGTGCAGGAGCTTGATGAAGAGCTGTTACAAGATGAGATGCCCGAGGCCCAGAAGGCC AAGGCTAAATGGACCCAGCTCGAAGCGCTCGTGGGCAGTCAGGAGCGGCTTAAGCAAATCGCCAATGATATTGTGACCCA CTTTGAAGCCCGGCAGGAAGTGTTCGAAGGCAAGGGGCTCATTGTTACCATGTCCAGAAGAATTGCCGCGGCCCTGTACG ATGAGATTATCCACATCCGCCCTGCCTGGCATAGTGATGACCTTAAAAAGGGTGCGATTAAAGTGGTGATGACTTCGGCC TCCTCCGACGGGCCTGAAATCGCCAAGCATTATACCAGCAAGGAAGACCGCCGCCTGCTTGCGGAGCGGATGAAGGACCC CCAGGATGAGCTTAAGCTCGTGATTGTTCGGGATATGTGGCTCACCGGTTTTGATGTTCCCTGTTTGCATACCATGTATA TCGATAAACCGATGAAGGGCCACACGTTGATGCAGGCCATCGCCCGGGTCAATCGGGTTTATAAAGACAAGCCCGGCGGC CTCATTGTGGACTACCTCGGTATCGCCGCCGATTTAAAGGAAGCCCTCTCATTTTATGCCGACAACGGCGGCAAGGGGGA CCCCGCATTGCTCCAGGAAGAAGCGGTGCGGCTCATGCTGGAAAAATACGAAATAGTTACGGACCTGCTTCATGGTTTTG CCTATAAGCACTATTGTACCGCCGATACCGCCGCAAAACTTTCGATAATTCTGGAAGCCGAAGAGTTTATATTAGGCCTT GAAAACGGAAGAAAGCGTTATATTGATGAAGTGACAGCCCTCTCTAAGGCCTTTGCCATAGCTATTCCAGACGAACAGGC CCTGGCGATAAAAGATGAAGTTGCCTTTTTCCAGGCGGTAAAATCCCGGCTCGTAAAATTTGCAGGCACCAGCGGAGGCA AAACCAATGAAGAAATCGAAACCGCTATCCGGCAGGTCATTGATAAGGCCCTGGTTACGGGTGAAGTAATCGATGTCTTT GATGCCGCTGGTATAAAAAAGCCTGATATCAGCATCCTTTCAGAGGAGTTTCTGTTAGAAGTTAAAAATATGAAACATAA AAATATCGCCATGGAGGTTCTTAAAAAAATCTTGAATGATGAAATTAAGGCCAGAACGAGAACAAACCTGGTGCAGAGTA AGAGCCTTTTAGAACTTCTTGAAAATGCCATTAAACGGTATCAGAACCAGGTGCTTACCGCAGCACAGCTCATAGAAGAA CTCATCGATCTTGCAAAGGATATTAAGAAGATGGACGAGGAGCCCGAGGCAATGGGGCTTTCTGAATTTGAATATGCCTT TTATTCCGCGGTAGCAAATAACGAAAGCGCCCGGGAGCTCATGGGTAAGGACAAGCTTAGAGAATTGGCGGTCGCACTCT ATGAGCAGGTACGGCAAAATGCATCTATCGATTGGACAATTAAGGAAAGCGTCAGGTCAAAACTCAAGGTTGCGGTAAAG CGCACCCTTAAGCGCTACGGCTATCCGCTCGATATGGAAGCCCTGGCAACCGAAACAGTCCTCAAGCAGGCGGAACTCAT TGCCGATGAACTGTGCGCGTAG Protein sequence : MPHHNLTESAIEDLAIKLFKSLGYHHLYGPDSAPEGKHPERSSFEDVILVNRLRDAVKKINPHIPQQSLDDAIRQVLRFP SQELIANNQSFHRLLTEGVKISYHKDGSERGDLVWLIDFKHPENNEFVVVNQFAVIENHQNKRPDVVLFVNGLPLVVIEL KNAADENATIQSAYNQIQTYKQAIPGFFTYNEIIVISDGLEARSGSLSAGLDRFVAWKSVDGRIEASSLESQLTTLIKGM LTPLTLIDIIRHFIVYEASKHEDPETGLTVIRTVKKIAAYHQYYAVNRAVASTIRAAGYEQAAQLPVAAPWPASLKEDPE AYGLPSVREQPVHDKKAGVIWHTQGSGKSLSMVFYTGKVVLTLDNPTVVVITDRNDLDDQLFTTFAASKQLLRQEPVQAE SRDHLKQLLRVASGGIVFTTIQKFQPDEGNVYDVLSNRNNIIVIVDEAHRTQYGFQAKVDANTGAITYGFAKYLRDALPN ATYIGFTGTPIEKTDRNTPAVFGNYIDIYDIAQAVADGTTVRIFYESRLAKIALSDEGKKLVQELDEELLQDEMPEAQKA KAKWTQLEALVGSQERLKQIANDIVTHFEARQEVFEGKGLIVTMSRRIAAALYDEIIHIRPAWHSDDLKKGAIKVVMTSA SSDGPEIAKHYTSKEDRRLLAERMKDPQDELKLVIVRDMWLTGFDVPCLHTMYIDKPMKGHTLMQAIARVNRVYKDKPGG LIVDYLGIAADLKEALSFYADNGGKGDPALLQEEAVRLMLEKYEIVTDLLHGFAYKHYCTADTAAKLSIILEAEEFILGL ENGRKRYIDEVTALSKAFAIAIPDEQALAIKDEVAFFQAVKSRLVKFAGTSGGKTNEEIETAIRQVIDKALVTGEVIDVF DAAGIKKPDISILSEEFLLEVKNMKHKNIAMEVLKKILNDEIKARTRTNLVQSKSLLELLENAIKRYQNQVLTAAQLIEE LIDLAKDIKKMDEEPEAMGLSEFEYAFYSAVANNESARELMGKDKLRELAVALYEQVRQNASIDWTIKESVRSKLKVAVK RTLKRYGYPLDMEALATETVLKQAELIADELCA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 47 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 47 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 47 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 46 |
