Gene Information

Name : Spica_2015 (Spica_2015)
Accession : YP_004698651.1
Strain : Treponema caldaria DSM 7334
Genome accession: NC_015732
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit clpA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2260884 - 2263325 bp
Length : 2442 bp
Strand : -
Note : -

DNA sequence :
ATGCAAATCAGCCGCCATGTGCAGGCTATAATCAATGCCGCTTATAATGAAGCCAAGGTTCGGAATCACGAATATTTAAC
CCCCGAACATGTGCTTTATGCCGCCCTGGCCTTTGAGGAGGTTCAGCAGGTTCTGCTCGCCTGCGGTGCGGATCTGAACC
AGATAAAAAGCGGTATGGAAAACTATTTTGAGCAGAAAGTTCCGGTGGTCCAGAACATGGAACCTACCCAGACGGTGGGG
TTTCAGAGCGTACTTGAACGGGCGGTACTCCAAAGCCAATCGGCCCAAAAAAAAGAACTCGATGTGGCTGATATTCTCGT
GTCCCTCTATGATGAGGAGCGTAATTACTGTGCCTATTATCTGCGTAAAGCCGGTGTAAAACGGATTGACCTTCTTGAGG
TGCTTTCCCATGGGATCCGTTTTGGGGATGAATCGGAAGAGGAGGGGGATAATGGGGACCCAGCCGCTTCAGGCTCATGG
AAAGAAAAAAATGAAGAGAACGGAGAAGATGCAGAGGCTGATAGCGGTATCGAGGCTGAACCGCGCATGCGGCCGGCCCG
TAAGAGTGCCCTAGAGCGGTTTACTACTGACCTGACTGCCCTGGCTCGGGAGGGCAAGCTCGAGCCTGTGATTGGCCGGG
AACACGAACTGGATCGAACGGTCCAGGTCCTGTGCCGCCGCCTGAAAAATAATCCCATCCATGTGGGGGATTCCGGTGTG
GGGAAAACCGCCATTACCGAGGGGCTTGCCCAGCGAATTGTGGCAGGCAATGTGCCGCCGACCTTGAGGGGATTTTCAAT
CTACGCTTTGGACATGGGTGCCCTTGTGGCAGGAACCAAGTACCGGGGTGATTTTGAGGAACGAATTAAGAAGGTGGTGG
ATGAAATCCTGAAAAAAGAAAAGGCCATCCTTTTTATTGATGAAATTCACACCCTGGTGGGTGCCGGTGCGACTTCAGGG
GGCTCCCTGGATGCCTCGAATTTACTGAAACCTGCGCTGACCTCAGGCAAGATTCGCTGTATTGGCTCCACAACCCACGA
AGAATACACCAAGTATTTCGATAAGGACCGGGCGCTTTCGCGCCGGTTCCAGAAAATTGATATAAACGAGCCCAGTGAGG
CCGATGCGATTGCGATTCTTAAGGGGCTCCGGCACAAATATGAAGAATTCCACCGCGTTCGCTATACCGATGCGGCCCTC
GAAACGGCGGTGCGCCTCTCTGCCCAGTTTATCACCGAGCGGCGTCTTCCCGATAAGGCCATCGATGTGATCGATGAGGC
CGGTGCCTTTGCCCGGATCCAGGCCTTTAAGGCTCGGGAAAATCAGGATGCAGAGACAGCGGGGGAAGTCCGGGTAGACA
CCAATGTCCCCACCACCGCAGAATCTCAGGCAGAGGCCCAGACAGATACAGAGGCAGCCTTTGCCCCTGAAAACCTGGAT
GCTCTGCCTATTATAGAGATTGATGTTCCTCAGATCGAAACTGTGGTAGCCCGGATTGCCCGGATTCCCGAACGCACGGT
TGGAGAAAATGAAAAGGATAAGCTCCGGTTCCTCGAAAGCCGCCTCAAGGAGCGAATCTTCGGCCAGGATGCGGCGGTCG
AAGCCGTCGTTCGGGCGGTAAAACGATCCCGGGCTGGATTCCGTGCTCCCAATAAGCCCATTGCCAATTTCCTCTTTGTT
GGTCCTACGGGGGTAGGTAAAACTGAGCTCGCCCGGAGTCTGGCGGATGTGTTGGGCATTGCCATGCATCGCTTTGATAT
GAGTGAATATCAGGAAAAGCATACCGTGAGCAGGCTTATTGGGTCTCCTCCCGGGTATGTGGGATATGAAGAGGGCGGGC
TCTTAACCGATGCGGTTCGCAAGCAGCCCCATGCGGTGGTTCTGCTGGACGAAATAGAAAAGGCCCATCCGGATATCTTC
AACATACTTTTACAGATTATGGACTATGCTACATTGACCGACAACAACGGCAGAAAAGCCGACTTCCGCAATGTGGTGCT
TATCATGACCAGCAATGCCGGTGCCCGGGATATCGGCAAAAGCCTCATTGGTTTTGGGGAACGGATCCTCGATGAGGCGG
TGGTGGATGGGGCGGTAGAGCGGATCTTTACCCCCGAATTCCGAAACCGCCTGGATGCGGTGGTCCGCTTTGGCCACCTG
AACCAGGACATTGTGGCATCCATAGTCCGCAAGGAATTGGACGCCTTCAGGATGCAGTTGGCTGAAAAGCAGGTTGTGCT
GGAAGTGACCGAGACCTGTATCATGCAGCTTGCTAAGGATGGATACAGTCGTGAATTCGGCGCACGCAATGTGAGCAGAC
TAATAGAAGATAAAATTAAGAGCTTCTTTGTAGATGAGGTCCTCTTTGGCCGGCTTGCCTCTGGCGGAGTGGCCCGCGCA
GACTGGTCCAACGGTGCATACCGTATCGAGGTGGTTTCCTAA

Protein sequence :
MQISRHVQAIINAAYNEAKVRNHEYLTPEHVLYAALAFEEVQQVLLACGADLNQIKSGMENYFEQKVPVVQNMEPTQTVG
FQSVLERAVLQSQSAQKKELDVADILVSLYDEERNYCAYYLRKAGVKRIDLLEVLSHGIRFGDESEEEGDNGDPAASGSW
KEKNEENGEDAEADSGIEAEPRMRPARKSALERFTTDLTALAREGKLEPVIGREHELDRTVQVLCRRLKNNPIHVGDSGV
GKTAITEGLAQRIVAGNVPPTLRGFSIYALDMGALVAGTKYRGDFEERIKKVVDEILKKEKAILFIDEIHTLVGAGATSG
GSLDASNLLKPALTSGKIRCIGSTTHEEYTKYFDKDRALSRRFQKIDINEPSEADAIAILKGLRHKYEEFHRVRYTDAAL
ETAVRLSAQFITERRLPDKAIDVIDEAGAFARIQAFKARENQDAETAGEVRVDTNVPTTAESQAEAQTDTEAAFAPENLD
ALPIIEIDVPQIETVVARIARIPERTVGENEKDKLRFLESRLKERIFGQDAAVEAVVRAVKRSRAGFRAPNKPIANFLFV
GPTGVGKTELARSLADVLGIAMHRFDMSEYQEKHTVSRLIGSPPGYVGYEEGGLLTDAVRKQPHAVVLLDEIEKAHPDIF
NILLQIMDYATLTDNNGRKADFRNVVLIMTSNAGARDIGKSLIGFGERILDEAVVDGAVERIFTPEFRNRLDAVVRFGHL
NQDIVASIVRKELDAFRMQLAEKQVVLEVTETCIMQLAKDGYSREFGARNVSRLIEDKIKSFFVDEVLFGRLASGGVARA
DWSNGAYRIEVVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-125 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spica_2015 YP_004698651.1 ATP-dependent Clp protease, ATP-binding subunit clpA VFG0079 Protein 1e-131 46
Spica_2015 YP_004698651.1 ATP-dependent Clp protease, ATP-binding subunit clpA VFG0080 Protein 5e-115 42