Gene Information

Name : Spica_1844 (Spica_1844)
Accession : YP_004698489.1
Strain : Treponema caldaria DSM 7334
Genome accession: NC_015732
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2028867 - 2031437 bp
Length : 2571 bp
Strand : -
Note : -

DNA sequence :
ATGAACTACGACAAACTTACCATAAAAGCCCAGGAGGCGCTCCAGGAGGCCTCCAGCATCGCCCAGAAAAATGACCAGAC
CCAGGTGGAACTGGAACATATCCTGCTTGCCCTGGTGGAGCAGGAAGGGGGCATTGTCGCACCGATAATCGAAAAAATTG
GTGCTGACCCGGAACTAATTTTACAGGAAGCCCGTAAATTGGTGGCTTCCAAACCAAAGGTATACGGAGAGGCGGCCCAG
CTGTACTTCTCGCCCGCCGCAAGCAAGGTCCTTGCCAAGGCAGAAGCGGAAGCCGCATCCCTTAAGGATGATTTTGTTTC
CACCGAACACATCCTTATCGCCATGACCCAGGCCGAAGGCCCCGCCACGGATATACTCAGGCGGAACGGCATCACCAAAG
AGGCCATCCTTTCGGCCCTGAAATCGGTCAGGGGTAACGCCCGGGTAACGGACCAGAACCCGGAAGAAAAGTACCAGGTC
CTGGACAAATACTGCCGGGACCTTACCGCCCTGGCACGGCAGGAAAAACTGGACCCGGTCATTGGCCGGGATGAGGAAAT
CCGCCGGGTAATGCAGGTCCTCTCCCGGCGCACCAAAAACAACCCGGTCCTCATCGGTGAACCAGGGGTCGGTAAAACCG
CCATTGTAGAAGGCCTCGCCCGACGCATTGTCGAAGGGGACGTCCCCGAGGGGCTTAAAAATAAACGGCTCCTCGCCCTG
GACCTGGGAGCCCTGGTGGCGGGTGCAAAATTCCGCGGCGAATTCGAGGAACGCCTAAAGGCAGTTATCCATGAAGTACA
GGCCGCAGAGGGAAGAATCATCCTCTTTATTGATGAACTCCATACCCTTGTGGGGGCGGGAGCCGCCGAGGGTGCCACCG
ATGCAAGCAACCTCCTTAAGCCTGCCCTGGCCCGGGGTGAACTTCGCTGTATCGGGGCTACTACCCTGGACGAATACCGC
AAGTATATCGAAAAGGATGCGGCCCTGGAGCGGCGTTTCCAGCAGGTTTACTGCGCCGAACCTTCCGTAGAGGACACCAT
CGCCATCCTGCGGGGGCTTAAGGAACGCTACGAAGTGCACCATGGGGTGCGCATTAAGGATGAAGCCCTGGTGGCCGCGG
CGACCCTGTCGACCCGGTATATCACCAGCCGCTTCCTCCCCGATAAGGCCATCGACCTGGTGGATGAGGCGGCGAGCCGC
CTTAAGATGGAACTGGACAGCCGTCCTACCGAATTGGACAAGCTGGAACGGAAACTCCTACAGCTTTCCATAGAACGGCA
GGCCCTACAGCGGGAAGACGACCCCGCTTCGGTAGAACGGCGACAGAAACTGGAAAAGGAAATCGCCGACCTCACCGCCG
AACGGGACGCCATGCGGGCCCGCTGGGAAAGTGAACGGAAGGATATCCAGGAACTGCGGCTCCTGAAGCAGAGAATAGAA
GAGCTTAAAATTGAGGAAGCCCGTTACGAGCGGGAGGGCAACCTGAATAAGGCCGCAGAAATTAAATACGGTCTCATCCC
CGAAGCCCAGCGGAAGCTAAAGGAAATTTCCGACCGCATGGAGGCTAAACGGGGCGAGGTAAGCCTCCTCCGCGAAGAGG
TGAGCGAAGAGGACATCGCCGCCGTTGTATCGAGCTGGACCGGTATTCCCGTATCCAAGATGCTTTCCAGCGAATTGCAG
AAGTATCTGGAACTGGAAAAGGTTCTCGAAAAACGGGTGGTCGGTCAGGATGCGGCGGTGCAAGCCGTGGCCGATGCCAT
CCGGCGCAACAAGGCGGGCTTAAGCGATGCCGCCCGGCCCCTGGGGTCCTTCCTCTTCCTGGGACCCACCGGTGTAGGTA
AAACCGAGCTGGCTAAGACCCTGGCAGAATTCCTCTTTAACGAGGAAAAGGCTTTGACCAGGATTGATATGAGCGAGTAC
GGTGAAAAACACACCGTAAGCCGCCTCATCGGTGCCCCTCCGGGCTATGTGGGCTATGAGCAGGGGGGCCAGCTTACCGA
AGCGGTCCGCCGCAGGCCCTACAGTGTGGTCCTCTTCGACGAAATCGAGAAGGCCCATCCGGATGTGTTCAACGTGTTCC
TCCAGATTCTGGATGATGGACGCCTGACCGACGGCCAGGGCAGGGTAGTGGACTTCAGGAACGTGATTATCATAATGACG
AGCAACCTGGGTTCGGACCTGATCCTGAACGCCAGGAGCACCGAAGAGATTCGTGGTGCCCTGCAGGAACTTCTTAAGGC
TTCATTTAGGCCCGAGTTCCTGAACCGGATTGATGAAACGGTCATCTTTAACCGGCTTGGACAGGCTGAGATTCACAAGA
TTGTGGATATCCAGCTGAATCGTCTGGCCCAACGGCTCGAGGATCGCAAGATTCGGCTCACGGTTACCGATGCGGCCAAG
TCCTTCCTGGCAGAGCGGGGCTACGATCCCCTGTACGGTGCCCGGCCCCTTAAGCGGACCATCCAGGCGGAACTGGAAAA
TCCGCTGGCCCGGGAAATCATCTCCGGCCGCTACAAGGAAGGTTCTGAGGTGTTGGTAGACCGGAATGGAGATGGGCTTT
TATTTAGATAA

Protein sequence :
MNYDKLTIKAQEALQEASSIAQKNDQTQVELEHILLALVEQEGGIVAPIIEKIGADPELILQEARKLVASKPKVYGEAAQ
LYFSPAASKVLAKAEAEAASLKDDFVSTEHILIAMTQAEGPATDILRRNGITKEAILSALKSVRGNARVTDQNPEEKYQV
LDKYCRDLTALARQEKLDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVEGDVPEGLKNKRLLAL
DLGALVAGAKFRGEFEERLKAVIHEVQAAEGRIILFIDELHTLVGAGAAEGATDASNLLKPALARGELRCIGATTLDEYR
KYIEKDAALERRFQQVYCAEPSVEDTIAILRGLKERYEVHHGVRIKDEALVAAATLSTRYITSRFLPDKAIDLVDEAASR
LKMELDSRPTELDKLERKLLQLSIERQALQREDDPASVERRQKLEKEIADLTAERDAMRARWESERKDIQELRLLKQRIE
ELKIEEARYEREGNLNKAAEIKYGLIPEAQRKLKEISDRMEAKRGEVSLLREEVSEEDIAAVVSSWTGIPVSKMLSSELQ
KYLELEKVLEKRVVGQDAAVQAVADAIRRNKAGLSDAARPLGSFLFLGPTGVGKTELAKTLAEFLFNEEKALTRIDMSEY
GEKHTVSRLIGAPPGYVGYEQGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNVFLQILDDGRLTDGQGRVVDFRNVIIIMT
SNLGSDLILNARSTEEIRGALQELLKASFRPEFLNRIDETVIFNRLGQAEIHKIVDIQLNRLAQRLEDRKIRLTVTDAAK
SFLAERGYDPLYGARPLKRTIQAELENPLAREIISGRYKEGSEVLVDRNGDGLLFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-101 45
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 8e-102 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 6e-102 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spica_1844 YP_004698489.1 ATP-dependent chaperone ClpB VFG2076 Protein 5e-114 44
Spica_1844 YP_004698489.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-104 42