Gene Information

Name : Spica_1243 (Spica_1243)
Accession : YP_004697897.1
Strain : Treponema caldaria DSM 7334
Genome accession: NC_015732
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1400377 - 1402923 bp
Length : 2547 bp
Strand : +
Note : -

DNA sequence :
TTGTTTAAAGGTCTTACCCAACGGGCACAACGAATACTTACCGTAATAGCCCAGGATGAAGCTCGACGTTTTCATAGCGA
TCAGCTTCTTCCTGAACATATACTTGTTGCTGTGATTAGGGACGGATCTGGTACAGCCTGCAGAGCTTTGGAAGATTTAG
CCATAGATTTGCAGGATTTCCGTCATGTTTTAGAACGGGAAATTCCGCAAAAGACCGGTACCTTTATTTTCGGGGATGTA
CCGCCTTCCCGCCGGGCTCGAACCTTACTCGAAGCTGCCGCTGAGGAAGCCCGCAGTTTTGGTCATGAATATGTAGGTAC
TGAACATTTATTGCTCGCGTCCATAAGAGAGGAGAATTCTCCTGCAGCACGGTATTTAGTGGAAAAACATATTAGCCCAG
AAATGCTTCGTTCCACAGTGCAACTCGTACTTGGGCAGATTCGGGATGATGGTCCTGTTGAAGACCCCCGGGATAGCGCC
CATACGGCCGGTTCAAATCCTTTCGGGACAGGAACACCAAGCGGGCAAAAGAACACCCGGACGCCCATTATCGATGAATT
TTCCCGGGACCTTACGGCCATGGCCCGGCTTGGTTCCTTGGATCCCGTCATTGGCCGTGAAAAGGAGGTTCGCCGGGTAG
TACGGATTCTTGCCCGACGAACTAAGAATAATCCGATCCTTGTAGGCGAACCTGGTGTGGGCAAAACCGCCGTAGTCGAA
GCCCTGGCCCAGCTTATTGCATCTGAAAATGTTCCAGAAATATTAGCGGATAAACGACTCCTTGCCCTCGACCTAGCCTC
GGTAGTGGCCGGAACAAAATACCGCGGCGAGTTTGAGGAACGGCTCAAAAAAATCATGAAGGAAATCAGTCAGGCGGGAA
ATATCATCCTCTTTATTGATGAAATTCATACGGTTATCGGTGCCGGTGGTGCGGAAGGTACTATCGATGCCTCTAACATG
CTCAAGCCCGCCCTTTCCCGGGGAGAAGTTCAGTGTATTGGCGCTACAACCCTCGCTGAATATCGGAAGCACTTTGAAAA
GGATGCGGCTCTCGAACGGCGTTTCCAGATGGTACCCGTAGAAGAGCCAAGTCTTGAAGAAACTATACAGATTCTTAAAG
GAATCAAGAAACGCTACGAGGAACATCACCGTGTTATCTATAATGATGGAGCAGTTTTAGCGGCGGCAACCCTGGCCCAG
CGCTATATCACCGGCCGGTTCATGCCCGATAAGGCGATTGATCTTTTGGATGAAGCTGGGGCGAAACGAAAACTCGAAAC
CGATATCAAGCCCGCCGAATTAAGTGAAATAGAAAACGAAATTAAACGGCTTACGGAAGAAAAGGTTCGCCTTGTGGCCG
CCCAGGACTATGAAAAGGCTGCAGAACTGAGGGACCAAGTCCGGTCCCTCAGGTACCAGCTCGAATCGGTAAAACAGGCC
TGGGAACGTCTTTCCCGGGAAGAACGGCCTGCAGTTACCGAAGCTGACATACGTCAGGTTGTTGCGGAAGCCACAGGAAT
CCCCCTGGCACGGCTCGAAGAAAGTGCATCCCGTAAACTGTTACGGATCGAAGAAGAACTGCACCGTTCGGTTATAGGAC
AGGACGATGCGGTTCAGCGGATTGCTGCGGCCATCCGGCGCAGCAGGGCAGGGGTATCTTCTCTCAAACGCCCCCAGGGG
TCATTTATATTCTTAGGGCCCACCGGGGTCGGTAAAACCCTTTTGGCAAAACGCCTTGCGGAGTATCTTTTTGGAACCGA
AGAAGCCCTGGTTCGCATAGATATGTCTGACTATATGGAAAAACACAATGCCTCCCGTCTTGTTGGAGCTCCCCCCGGCT
ATGTAGGGTATGAAGAAGGCGGGGTGCTTACAGAAAAAATCCGTCGAAATCCCTATCGGGTTATCCTTTTTGATGAAATA
GAGAAAGCCCACCATGATGTCTTTAATCTTTTGTTACAGGTTTTGGAAGAGGGGGAACTCAAGGATAATCTGGGGCATAC
GGTAAGTTTCCGGAATACGGTCATCATTATGACGAGCAATGCAGGGGCCCGTGAAATTTCCCGAGATGCTCGCCTTGGAT
TTAACCCCGATTCGGGCATTATGAACCTGGAAGAAATCCGCTCAGCCGCCCTGGCAGAACTTAAGCGTCTCTTTAACCCT
GAATTCATTAATCGGGTTGATGATATTGTCGTGTTCCATGCCTTGAGCCGCGAACAGGTTCAGGCAATCCTGGCCCTTGA
AATTCAGGAATTGAATAAACGGCTCCATGACCAGGGGTACTCGATTCAGGTTAAACAGAGTGCCCAGGATATTTTAATAG
AAAAGGGCTGGGATCCCAAATATGGCGCCCGTCCCATGCGCCGGGCTATCCAAAAAGAATTAGAGGATGTCCTGGCCGTG
TTAATTCTTGAACAGGAATATCCCGCTGGAACAATATTTATAGCCGAAGACCGGGATGGAAAAATCAGCATCAAATCAAA
AAAGAATAAGCCGACCCTGCTAACCACGGTTCCGGCTGTTTCCTCAGAACCGATTAGCAAATCCTAG

Protein sequence :
MFKGLTQRAQRILTVIAQDEARRFHSDQLLPEHILVAVIRDGSGTACRALEDLAIDLQDFRHVLEREIPQKTGTFIFGDV
PPSRRARTLLEAAAEEARSFGHEYVGTEHLLLASIREENSPAARYLVEKHISPEMLRSTVQLVLGQIRDDGPVEDPRDSA
HTAGSNPFGTGTPSGQKNTRTPIIDEFSRDLTAMARLGSLDPVIGREKEVRRVVRILARRTKNNPILVGEPGVGKTAVVE
ALAQLIASENVPEILADKRLLALDLASVVAGTKYRGEFEERLKKIMKEISQAGNIILFIDEIHTVIGAGGAEGTIDASNM
LKPALSRGEVQCIGATTLAEYRKHFEKDAALERRFQMVPVEEPSLEETIQILKGIKKRYEEHHRVIYNDGAVLAAATLAQ
RYITGRFMPDKAIDLLDEAGAKRKLETDIKPAELSEIENEIKRLTEEKVRLVAAQDYEKAAELRDQVRSLRYQLESVKQA
WERLSREERPAVTEADIRQVVAEATGIPLARLEESASRKLLRIEEELHRSVIGQDDAVQRIAAAIRRSRAGVSSLKRPQG
SFIFLGPTGVGKTLLAKRLAEYLFGTEEALVRIDMSDYMEKHNASRLVGAPPGYVGYEEGGVLTEKIRRNPYRVILFDEI
EKAHHDVFNLLLQVLEEGELKDNLGHTVSFRNTVIIMTSNAGAREISRDARLGFNPDSGIMNLEEIRSAALAELKRLFNP
EFINRVDDIVVFHALSREQVQAILALEIQELNKRLHDQGYSIQVKQSAQDILIEKGWDPKYGARPMRRAIQKELEDVLAV
LILEQEYPAGTIFIAEDRDGKISIKSKKNKPTLLTTVPAVSSEPISKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-175 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spica_1243 YP_004697897.1 ATPase VFG0079 Protein 0.0 51
Spica_1243 YP_004697897.1 ATPase VFG0080 Protein 8e-147 51