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Name : clpB (HYPMC_4912) Accession : YP_004678684.1 Strain : Hyphomicrobium sp. MC1 Genome accession: NC_015717 Putative virulence/resistance : Virulence Product : protein disaggregation chaperone Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 4722317 - 4724908 bp Length : 2592 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor DNA sequence : ATGAACTTCGAACGCTACACGGACCGCGCCAAGGGCTTTATCCAATCGGCTCAATCGCTGGCACTCCGCGAAAACAATCA ACAGGTCACCCCCGAACATCTTCTGAAAATTCTGCTCGATGACCCGGAGGGTCTAGCCAGCGGACTGATCCAGAAGGCGA GCGGGGATTCGCGCGCCGCATTGCGCGCGGTCGAGGCGAACCTTGCCAAGAAGCCAAAGGTCACCGGCGGCTCGGGACAG GTTTACGTCTCGTCGGAACTCGCACGCGTGTTCGACGCCGTCGAGAAACTTGCCGACAAGGCGAGCGACAAGTTCGTCAC CGCCGAGCGGCTGCTTTTGGCGCTGGCGCTCGACACCGCGACGGACGCGGGCAAGATCCTGCGCGACGCCGGTGTGACGC CCGACAAGATCAACGCCGCCATCAACGACATCCGCAAGGGCCGCACGGCCGACAGCGCCAACGCCGAGCAGGCGTATGAC GCTCTGAAGCGCTATGCCCGCGACCTCACCGAAGCGGCAGGCTCCGGCAAGCTCGATCCGGTTATCGGCCGCGACGAAGA GATCCGCCGCACCATCCAGGTGCTGTCGCGGCGCACGAAGAACAATCCCGTGCTGATCGGCGAACCGGGCGTCGGCAAGA CGGCGATCGCGGAAGGCCTCGCGCTGCGCATCGTCAAGGGCGACGTGCCGGAAAGCCTGAAGCATAAGAAGCTGCTGTCG CTCGATATGGGCGCCTTGATCGCGGGCGCGAAGTATCGCGGCGAGTTCGAGGAACGCTTGAAAGCCGTGCTGTCCGAGGT CGAGGCCGAGGGCGACATCATTCTGTTTATTGACGAGCTGCATACCATCGTCGGCGCCGGCAAGACCGAAGGGTCGATGG ATGCGGGCAACCTGTTGAAGCCTGCGCTCGCGCGCGGCGAGCTTCACTGCGTTGGTGCGACCACGCTGGATGAATACCGC AAGCACATCGAAAAGGACGCCGCGCTCGCCCGCCGCTTCCAGCCGATATTCGTAACCGAACCGACGGTGGAAGATACGAT CTCGATCCTGCGCGGCTTGAAAGAGAAGTATGAGCTGCATCACGGCGTGCGCATCACCGACAGCGCGCTCGTCTCGGCGG CGACGCTTTCGAACCGCTACATCACCGACCGCTTTCTGCCCGACAAGGCGATCGACCTTGTCGACGAGGCGGCGTCGCGT CTGCGCATGCAAGTCGATTCCAAGCCGGAAGAGCTCGACGCCATCGACCGCGATCTCATGCAGATGATGATCGAGCGCGA AGCGTTGAAAAAGGAAACCGACTCGGCATCGAAGGATCGTCTCGCGCGGCTTGAGAAATCCATCGCCGATCTGCAGGAAA AATCCGAGGCGATGACGGCGCGCTGGCAGGCCGAGAAGCAAAAGCTCGGCTCGGCGCAGAAGCTGAAGGAAGAGCTTGAG AGCCTGCGCAACGCGCTCGAACAGGCGCAGCGCAAGGGCGATCTGGCACGCGCGGGCGAGCTTCGCTACGGCAAGATCCC CGAGCTTGAGAAGAAGCTCGCCGACGTCGAATCCCAAGAGCGTAAGGGCGCGCTGGTCGAGGAAGCCGTCACGCCGGATC AGATCGCGGCCGTCGTGTCGCGCTGGACGGGCGTTCCGGTCGACAAGATGCTCGAGGGCGAACGCGACAAGCTTCTGAAG ATGGAAGATGCGCTGGGCAAGCGCGTCATCGGTCAGAAGGAAGCGGTCATCGCCGTTTCGACAGCTGTGCGTCGTGCGCG CGCCGGGCTTCAGGACCCGAACCGGCCGATCGGCTCGTTCATGTTCTTAGGACCGACCGGCGTCGGCAAGACCGAGCTGA CGAAGGCGCTCGCGGGCTATCTCTTCGACGACGACACGGCGCTCGTGCGCATCGACATGTCGGAGTTCATGGAGAAGCAC TCGGTCGCCCGTCTCATCGGCGCGCCTCCGGGTTATGTCGGCTACGAGGAAGGCGGCGTGCTGACGGAAGCGGTGCGGCG GCGTCCGTATCAGATCATCCTGTTCGATGAGATCGAGAAGGCGCATCCGGATGTCTTCAACGTGTTGCTTCAGGTTTTGG ACGACGGTCGCCTGACCGACGGCCAGGGCCGCACGGTCGACTTCAAGAACACGTTGATCGTGCTGACGTCGAACATCGGC GCGCAGTACCTCGTCGAGCAGAAGGAAGGCGAGGAAACGGAAGCCGTGCGCGACGAAGTCATGGCTGAAGTTCGCGCTCG CTTCCGGCCCGAATTCCTCAACCGTCTCGACGACATCATCCTGTTCCACCGCTTGCAGCGCGCGGACATGACGAAGATCG TCGATATCCAGATCGGGCGTCTGCAGAAGCTCTTGGCGGATCGCAAGATCACGATCGAGCTTGATGAGCAGGCGAAGACG TGGCTCGCAAACCGCGGCTACGATCCGGCGTATGGCGCGCGGCCTTTGAAGCGTGTCATCCAGCGCAACGTGCAGGACCC GCTCGCCGAGCAGATCCTTGCGGGCGGCGTGAAGGACGGCGATACGGTGACGGTGTCGGTGCGCGACGGTGCTCTGACGA TCAACGGCTGGCCGATCAAAGCCGCGGCTTGA Protein sequence : MNFERYTDRAKGFIQSAQSLALRENNQQVTPEHLLKILLDDPEGLASGLIQKASGDSRAALRAVEANLAKKPKVTGGSGQ VYVSSELARVFDAVEKLADKASDKFVTAERLLLALALDTATDAGKILRDAGVTPDKINAAINDIRKGRTADSANAEQAYD ALKRYARDLTEAAGSGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVKGDVPESLKHKKLLS LDMGALIAGAKYRGEFEERLKAVLSEVEAEGDIILFIDELHTIVGAGKTEGSMDAGNLLKPALARGELHCVGATTLDEYR KHIEKDAALARRFQPIFVTEPTVEDTISILRGLKEKYELHHGVRITDSALVSAATLSNRYITDRFLPDKAIDLVDEAASR LRMQVDSKPEELDAIDRDLMQMMIEREALKKETDSASKDRLARLEKSIADLQEKSEAMTARWQAEKQKLGSAQKLKEELE SLRNALEQAQRKGDLARAGELRYGKIPELEKKLADVESQERKGALVEEAVTPDQIAAVVSRWTGVPVDKMLEGERDKLLK MEDALGKRVIGQKEAVIAVSTAVRRARAGLQDPNRPIGSFMFLGPTGVGKTELTKALAGYLFDDDTALVRIDMSEFMEKH SVARLIGAPPGYVGYEEGGVLTEAVRRRPYQIILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTLIVLTSNIG AQYLVEQKEGEETEAVRDEVMAEVRARFRPEFLNRLDDIILFHRLQRADMTKIVDIQIGRLQKLLADRKITIELDEQAKT WLANRGYDPAYGARPLKRVIQRNVQDPLAEQILAGGVKDGDTVTVSVRDGALTINGWPIKAAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 4e-108 | 43 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 9e-109 | 41 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 7e-109 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_004678684.1 | protein disaggregation chaperone | VFG0080 | Protein | 2e-138 | 47 |
| clpB | YP_004678684.1 | protein disaggregation chaperone | VFG2084 | Protein | 3e-113 | 42 |
| clpB | YP_004678684.1 | protein disaggregation chaperone | VFG2076 | Protein | 5e-121 | 42 |
