Gene Information

Name : fliI (HYPMC_4353)
Accession : YP_004678126.1
Strain : Hyphomicrobium sp. MC1
Genome accession: NC_015717
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 4177964 - 4179331 bp
Length : 1368 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence : 
GTGAGCGCGGGCGCTGTAACGGCATTCGATCGCCTGGACCTTCTGATGGCAACCGCTGCCGCGCGGTCGCCCGCGCATCG
CGTTTCCGGCCGCGTGGTTCGTATCAGCACGACGTATCTCGTCGTTGCGGGCCTTTCGAAATTCGTATCGCTCGGGGATT
GCGTGTCGATTTCCGGCATCGGCGGCACAATCCTCGCCGAAGTTGCGACGATCGAAAGCCAGACAATCAACGTCACGCCG
TTTATCGCCGACCATCGAATCGAACTCGGCGCACGCGTTACGACGATGTCCGGACAACTGTCGCTGTCACCGGATGAATC
CTGGCTTGGCCGCACGGTCAACGCGTTGGGCGAGCCTATCGATGATGCCGGTCCGCTCGTTCGCGGAGAGCGTGCTTATG
CGGTTCAAGGTTCGCCGCCATCGCCGTTGCGTCGGAATAGGTTAGGAACGCCGCTGACGACGGGCGTCAAAGCCATCGAC
CTTTTCACGCCCATCTGCGCCGGGCAGCGCATCGGCATCTTTGCGGGCTCTGGCGTCGGCAAGTCGACACTGCTTGCGAT
GTTGAGCCGCGCACCTTCGAGCGACGTCACAGTGCTGGCACTCGTAGGCGAACGAAGCCGCGAAGTCCGCGATTTTCTTG
ACGATACGCTCGGCGCGACGCGCTCACAGGTGGTCTCAGTCGTCGCGACGTCCGACGAAAGCCCGATGATGCGTCGCCTC
GCGCCCAGCGCCGCCATGTGCATTGCCGAATACTACCGCGACCGCGGCAAGACCGTGCTGCTCATCATCGACTCGCTGAC
GCGATACGCGCATGCCATGCGTGAACTGGCGCTGGCCGCCGATGAGCCGCCCGTTGCGCGCGGTTACCCGCCGAGCGTCT
TCAGCAATCTGCCGAGGTTACTCGAACGGGCCGGACCGGGCGAAGCCGGCGCCGGAACGATCACAGCCATTTTGTCCGTT
CTCGTGGACGGCGATGACCATAACGATCCGATCGCCGACGCGACGCGCGGCATCCTAGACGGGCACATCGTCCTCGATCG
CAGCATCGCGAGCCAGGGCAGGCTGCCCGCGCTCGATCCGCTCGCCTCACTTTCGCGCCTCGCGCCGAAGATCAGGACAA
AGAACCAGACGCAATTTGTGACGCAATTGATCGAAGTGATTTCGCGCTACGAAGACACCAGAGATCTTCGCGCGATCGGC
GGCTATAAGGCCGGTAGCGATTTGACTCTCGACAAAGCCATGGAAATCGTGCCGCGCGTTTACGATGCTATGAAACAATC
TCTCGACGAAGATCCCGTCGATGACGTCTATACGTATCTTTCTCAGGTTCTCCAGGGCGGGCAACGGCAGCACACCGCAT
CGCGCTAA

Protein sequence : 
MSAGAVTAFDRLDLLMATAAARSPAHRVSGRVVRISTTYLVVAGLSKFVSLGDCVSISGIGGTILAEVATIESQTINVTP
FIADHRIELGARVTTMSGQLSLSPDESWLGRTVNALGEPIDDAGPLVRGERAYAVQGSPPSPLRRNRLGTPLTTGVKAID
LFTPICAGQRIGIFAGSGVGKSTLLAMLSRAPSSDVTVLALVGERSREVRDFLDDTLGATRSQVVSVVATSDESPMMRRL
APSAAMCIAEYYRDRGKTVLLIIDSLTRYAHAMRELALAADEPPVARGYPPSVFSNLPRLLERAGPGEAGAGTITAILSV
LVDGDDHNDPIADATRGILDGHIVLDRSIASQGRLPALDPLASLSRLAPKIRTKNQTQFVTQLIEVISRYEDTRDLRAIG
GYKAGSDLTLDKAMEIVPRVYDAMKQSLDEDPVDDVYTYLSQVLQGGQRQHTASR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-64 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-64 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-58 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-59 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-59 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-59 46
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-59 46
escN AAC31513.1 L0034 Virulence LEE Protein 2e-59 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-59 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-64 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-64 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-64 45
unnamed AAL06369.1 EscN Virulence LEE Protein 6e-57 45
escN AAK26715.1 EscN Virulence LEE Protein 2e-58 45
escN AAL57542.1 EscN Virulence LEE Protein 2e-58 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-58 45
escN AAC38383.1 EscN Virulence LEE Protein 3e-59 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-58 45
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-69 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-71 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-71 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-69 43
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-69 43
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-64 43
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-69 43
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 6e-69 43
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-69 43
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-69 43
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-69 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-59 42
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-59 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 7e-53 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-51 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-51 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-51 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-51 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-51 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-49 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_004678126.1 flagellum-specific ATP synthase VFG2144 Protein 2e-68 48
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0812 Protein 1e-59 46
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0515 Protein 9e-65 45
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0730 Protein 2e-59 45
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0192 Protein 3e-65 44
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0390 Protein 3e-64 44
fliI YP_004678126.1 flagellum-specific ATP synthase VFG2331 Protein 6e-65 44
fliI YP_004678126.1 flagellum-specific ATP synthase VFG1008 Protein 1e-50 43
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0048 Protein 5e-67 42
fliI YP_004678126.1 flagellum-specific ATP synthase VFG1254 Protein 2e-71 41
fliI YP_004678126.1 flagellum-specific ATP synthase VFG0555 Protein 1e-51 41