Gene Information

Name : ureC (HYPMC_3937)
Accession : YP_004677712.1
Strain : Hyphomicrobium sp. MC1
Genome accession: NC_015717
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 3769568 - 3771247 bp
Length : 1680 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 8288539; Product type e : enzyme

DNA sequence :
ATGTACGGTCCCACTCTTGGTGATGGAGTGAGGCTCGGTGATACCTCGTTGGTCGCGGTCATCGAAAAAGACCACGCCGT
CTATGGCGACGAATGTCTGCATGGCGGCGGCAAAACCCTGCGAGACGGAATTGGTCTCGCGGCCGGCGTGACGAGTCGCG
AAGGCGCTCTCGACTTCCTCTTATGCAACGTCACCGTGATCGATGCCGTGCTCGGTATCGTGAAAGGCGATCTCGGCATC
AAGGAAGGCAGGATCGTCGGAATCGGGAAGGCCGGAAATCCCGACATCATGGACGGTGTCGATTCGCGGCTTGTCGTGTC
GGCCGCAACGACAGTCCGCGATTGCGAGGGAATGATCGCCACTGCCGGCGCCATCGATGTTCACGTCCACTTCGACAGTG
CACAGCTATGCGAACACGCAATCGCGTCCGGTATTACGACGATGCTCGGCGGCTCGTTGGGACCAATCACTGTCGGTATT
GACTCCGGCGGCCCGTTTAACGTCGGCAAGATGCTGCAGGCGGCCGAGCACTGGCCGATCAACTTCGGCTTTCTAGGCCG
TGGCAATTCGCACAAACCGGCGTCTCTGGTCGAACAGCTTGAGACAGGGTGCCTCGGCCTGAAGCTGCACGAAGATTGGG
GCAGCATGCCAGCCGCCATCGATATGTGCTTGCGCGTTGCCGATGAACTGGATTTTCCGGTTCAGATCCACACCGACACG
CTCAACGAGTCCGGCTATCTTGAAAACACGTTGGCAGCGATCGGCGGACGTACAATTCATATGTACCACACCGAAGGTGC
CGGAGGCGGCCATGCGCCGGACATTATTCGCGTTGCGGGTGTTCCATGGTGTCTGCCTTCGTCGACCAATCCGACGAACC
CTTACACGGTAAATACGTTTGACGAACATCTCGACATGACGATGGTTTGTCATCACCTCAATCCGGCAATTCCCGAGGAT
GTGGCCTTCGCCGAGAGCCGGATCCGTGCGCAGACCATCGCAGCCGAAGATATACTGCATGACATCGGCGCCATTTCCAT
GCTCGGCTCGGACAGTCAGGGGATGGGACGTATCAACGAGGTCATTTGCCGGACGTGGCAACTCGCCGACAAGATGAAGC
GGCAGCGCGGCCGCTTGCCAGAAGAACAGACACGTTTCGGAGACAACGAGCGCATCAAGCGTTACATCGCCAAATATACG
ATCAACGCGGCCCGCACGTTTGGAATCGCGGAGCACATCGGCTCGCTGGAAGATGGCAAGATGGCTGACATCGTCGTCTG
GCATCCGGCATTTTTCGGTATTAAGCCTGAACTCATCATCAAAGGCGGATTCATCGCGTGGGGCGCTATGGGCGACAGCG
CTGCCTCTCTGATGACCTGCGAGCCGCGCATGCTGAGGCCGCAATGGGGCGCGTTCGGGCGCGCAAGCAAGGCTTTGTCG
GCGTGCTTCGTCAACCCATTGGCAATCAATGGCGGCATCGCCGAGGCGCTCGATTTGCAGAAGCCATTGCTCGCCTCCCG
TGGAACGCGAGACCTCTCAAAGAAGGATATGGTGCGCAACGATGCGTGCCCCGATATCCGTGTTGATCCGCAGACGTTTG
AGGTTTTTGTCGATGGGAAGTTGGCTACGTGTGGGCCGGCGCATGAATTGCCTCTCGCGCAGCGCTATATGTTGAGATGA

Protein sequence :
MYGPTLGDGVRLGDTSLVAVIEKDHAVYGDECLHGGGKTLRDGIGLAAGVTSREGALDFLLCNVTVIDAVLGIVKGDLGI
KEGRIVGIGKAGNPDIMDGVDSRLVVSAATTVRDCEGMIATAGAIDVHVHFDSAQLCEHAIASGITTMLGGSLGPITVGI
DSGGPFNVGKMLQAAEHWPINFGFLGRGNSHKPASLVEQLETGCLGLKLHEDWGSMPAAIDMCLRVADELDFPVQIHTDT
LNESGYLENTLAAIGGRTIHMYHTEGAGGGHAPDIIRVAGVPWCLPSSTNPTNPYTVNTFDEHLDMTMVCHHLNPAIPED
VAFAESRIRAQTIAAEDILHDIGAISMLGSDSQGMGRINEVICRTWQLADKMKRQRGRLPEEQTRFGDNERIKRYIAKYT
INAARTFGIAEHIGSLEDGKMADIVVWHPAFFGIKPELIIKGGFIAWGAMGDSAASLMTCEPRMLRPQWGAFGRASKALS
ACFVNPLAINGGIAEALDLQKPLLASRGTRDLSKKDMVRNDACPDIRVDPQTFEVFVDGKLATCGPAHELPLAQRYMLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-126 55
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-126 55
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-139 53
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-139 53
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-139 53
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 6e-139 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004677712.1 urease subunit alpha VFG0270 Protein 5e-130 54