Gene Information

Name : guaA (HYPMC_3211)
Accession : YP_004676992.1
Strain : Hyphomicrobium sp. MC1
Genome accession: NC_015717
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3082006 - 3083553 bp
Length : 1548 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3894345; Product type e : enzyme

DNA sequence :
TTGACCGATTCCGTCCTCATCATCGACTTTGGCAGCCAGGTGACGCAGCTCATCGCACGACGTGTGCGGGAGGCGGGCGT
CTACTCGGAAATTCACCCGTTCCAGAGCGCCGCCGAAGCGTTCCAGAAGCTGAAACCAAAGGCTGTGATTTTGTCGGGCG
GTCCGGCGTCCGTCACTGAGGCAGACTCGCCACGGGCGCCGTCGGCAGTGTTCGAAGCAGGCGTGCCGGTGCTCGGAATT
TGCTACGGCCAGCAGACCATGGCCGAACAACTCGGCGGCAAGGTTGAAAGCGGCCACGACCGCGAATTCGGCCGCGCCTT
CCTCTCAATTGCGACGCACAGCCCGTTATTCGAAGGCGTCTGGTCCAAGGGCGAGCGCTATCAGGTCTGGATGAGCCACG
GCGACCGCGTCACCAGTCTGCCGGAAGGTTTCGAAGTCATCGGCACCAGCGATAACGCACCATTCGCTGCGGTCGCGGAC
GAGAATCGCCGCTTTTATGCCGTGCAGTTTCACCCTGAGGTCGTTCACACGCCCGACGGCGCCAGGCTGATCGCCAATTT
CGTGCACAACATTGCAGGTCTGAAGTCTGATTGGACGATGTCGGCCTATCGCCGCGAGATGATCGCCAAGATCCAGAAAC
AGGTCGGCAAGAGCCGCGTGATTTGTGGGCTTTCGGGTGGCGTCGATAGCGCCGTCGCCGCCGTGCTGATCCATGAAGCG
ATTGGTGACCAGCTGACCTGCGTGTTCGTCGATCACGGCCTGATGCGGCTCGGCGAGGCGGACGAAGTCGTCGGCCTCTT
CCGCGATCACTACAACATTCCGCTCGTGCACGTGGACGCGTCCGAGCAGTTCCTGACAGCACTTGCAGGTGTCTCGGACC
CCGAGACCAAGCGCAAGACCATCGGCAAGCACTTCATTGACGTTTTCGAGGCCGAAGCCAAGAAGATCGGCGGCGCGGAG
TTCCTGGCCCAGGGCACGCTCTATCCAGATGTGATCGAAAGCGTGTCGTTCACCGGCGGCCCGTCAGTCACGATCAAGTC
GCATCACAACGTCGGCGGTTTGCCCGAGCGCATGAACATGAAGCTCGTCGAACCGCTGCGCGAGCTGTTCAAAGACGAGG
TGAGGGCACTGGGCCGTGAACTTGGCCTGCCGGAAACCTTCGTCGGTCGGCACCCATTTCCGGGGCCGGGTCTTGCGATC
CGCATTCCCGGCGAGATCACGCGCGAAAAACTCGACATCCTGCGTAAGGCCGACGCTGTTTATCTCGACGAAATCCGCCG
CGCCGGGCTTTACGATGCGATCTGGCAGGCGTTCGCCGTCCTGCTTCCCGTGCGAACTGTCGGCGTCATGGGCGACGGCC
GCACCTACGATCACGTTCTCGGCCTGCGCGCCGTCACATCCGTCGATGGCATGACCGCCGACTTCTTCCACTTCGACATG
GCGTTCTTGGGCCGCGTCGCCACCCGCATCATCAACGAGGTCCGCGGCGTCAACCGCGTTGTCTACGACGTCACGTCGAA
ACCGCCCGGCACCATCGAGTGGGAATGA

Protein sequence :
MTDSVLIIDFGSQVTQLIARRVREAGVYSEIHPFQSAAEAFQKLKPKAVILSGGPASVTEADSPRAPSAVFEAGVPVLGI
CYGQQTMAEQLGGKVESGHDREFGRAFLSIATHSPLFEGVWSKGERYQVWMSHGDRVTSLPEGFEVIGTSDNAPFAAVAD
ENRRFYAVQFHPEVVHTPDGARLIANFVHNIAGLKSDWTMSAYRREMIAKIQKQVGKSRVICGLSGGVDSAVAAVLIHEA
IGDQLTCVFVDHGLMRLGEADEVVGLFRDHYNIPLVHVDASEQFLTALAGVSDPETKRKTIGKHFIDVFEAEAKKIGGAE
FLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRALGRELGLPETFVGRHPFPGPGLAI
RIPGEITREKLDILRKADAVYLDEIRRAGLYDAIWQAFAVLLPVRTVGVMGDGRTYDHVLGLRAVTSVDGMTADFFHFDM
AFLGRVATRIINEVRGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-138 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-138 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-138 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-125 53