Gene Information

Name : puuC (HYPMC_2755)
Accession : YP_004676540.1
Strain : Hyphomicrobium sp. MC1
Genome accession: NC_015717
Putative virulence/resistance : Virulence
Product : Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.-
Position : 2605137 - 2606624 bp
Length : 1488 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15590624, 91216440; Product type e : enzyme

DNA sequence :
ATGACATCGCTTGCACACTTCGAAGCCGTTGCCGGATCGATCAAAATTCCGAGCGAAGCCGTCATCGACGGCAAGCTGAC
GGAGAGCGTTTCCGGCAGAACGTTCGCCAACATCTCACCGCGCGACGGGCGCGTCCTTAATCATGTCGCCCAGTGCGGGC
CGGAGGATGTCGATCTCGCCGTCAAAAGCGCGCGCCGCGCCTTCGATGAGGGATCGTGGCGTAAGCTGCACTATCGCGAG
AAAAAGCGCATTCTGTTCAAGCTCGCCGAACTGATGGAACGCGATATCGAAACGCTCGCCGTTCTCGAAAGCCTCGATGT
CGGCAAGCCGATCTCGAACGCGCTCGGCGGCGACGTTCCGAACGCCATCCGCTCGCTGCGCTATTATGCGGAAGCGCTCG
ATAAGGTTTACGGTGAAGTGGCGCCGGAAGCACCGGACCGGTTCTCGTTCGTCGTCCACGATCCGCTGGGCGTCATCGGC
GCCATCGTGCCGTGGAACTTCCCGCTGCACATGGCGATGTGGAAGGTCGCCCCGGCACTCGCGATGGGCAATTCCGTCAT
TCTGAAGCCTGCGGAGCAATCGCCGCTGACAGCGCTAAAGCTTGGTGAACTGGCGCTCGAAGCTGGAATTCCGGCGGGGG
TACTGAACGTTATTCCGGGCTTCGGCGCAGAAGCAGGCAAGGCGCTCGCGCTGCACAATGACGTCGACATGATTGCATTC
ACCGGCTCGGGCCCGGTCGGCAAGCTGCTCATGCAGTATTCGGGACAGAGCAACCTGAAGCGCGTCAGCCTGGAACTCGG
CGGCAAGTCTCCGCATATCGTGTTCGCGGACTGCCCCGATCTCGACCGCGCCGCCACGGAAGCGGCGTGGGGCATCTTCT
ATAATTCAGGGCAGGTATGCACTGCCGGGTCTCGTCTCTTGGTGCAGGACGCGATAGCCGATGATTTCACCAATCGGCTC
ATAACGGTTGCTCGAAAAATCGTTGCTGGTGACCCCTTGGAGCCCGCGACGACGTCGGGCGCTATGGTTAGCGAAGAACA
GATGAAGACGGCACTCCGCTATATCGAAACGGCGAAGCGCGAGGGCGGCACGCTGGCCCTCGGCGGCAATCGCACGCTCG
AAGGAAGCGGTGGGTTCTACGTCGAGCCGACGGTGTTTTCGGGCGTGACGCCCGAGAATACGCTGGCGCGCGAAGAAGTT
TTCGGACCGGTGCTCGCCATTACGCGTTTCACCGAAGCGGACGACGCCATCCGCATCGCCAACGATACGAACTATGGCCT
CGCCGCCGGTCTTTGGACCAAGGACATCACGCTGGCTCACCGCGCCGCCCGCGAGATCCGTGCCGGACTCGTCTGGATCA
ACGGCTGGGACAGCTGCGATATCACGATGCCGTTCGGAGGCTTCAAGCAATCGGGCTTCGGCCGTGATCGCTCTCTGCAC
GCACTACATAAGTATGCCGATTTAAAATCGGTCTCGATCACACTCTGA

Protein sequence :
MTSLAHFEAVAGSIKIPSEAVIDGKLTESVSGRTFANISPRDGRVLNHVAQCGPEDVDLAVKSARRAFDEGSWRKLHYRE
KKRILFKLAELMERDIETLAVLESLDVGKPISNALGGDVPNAIRSLRYYAEALDKVYGEVAPEAPDRFSFVVHDPLGVIG
AIVPWNFPLHMAMWKVAPALAMGNSVILKPAEQSPLTALKLGELALEAGIPAGVLNVIPGFGAEAGKALALHNDVDMIAF
TGSGPVGKLLMQYSGQSNLKRVSLELGGKSPHIVFADCPDLDRAATEAAWGIFYNSGQVCTAGSRLLVQDAIADDFTNRL
ITVARKIVAGDPLEPATTSGAMVSEEQMKTALRYIETAKREGGTLALGGNRTLEGSGGFYVEPTVFSGVTPENTLAREEV
FGPVLAITRFTEADDAIRIANDTNYGLAAGLWTKDITLAHRAAREIRAGLVWINGWDSCDITMPFGGFKQSGFGRDRSLH
ALHKYADLKSVSITL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-106 51
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-84 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-84 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-84 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-84 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-84 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
puuC YP_004676540.1 Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase VFG0082 Protein 1e-84 42