Gene Information

Name : dhaS (HYPMC_0195)
Accession : YP_004674013.1
Strain : Hyphomicrobium sp. MC1
Genome accession: NC_015717
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase dhaS
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 196751 - 198250 bp
Length : 1500 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology

DNA sequence :
ATGAATATCAATGTCACGATACCCACTCCGTCGGCCAAGACCCAAGAGTTCTTCGCGCGCAAGCACAAACTCTATATCGA
CGGCGCGTGGACGGAAGGCGTTTCGGGCGAAAGGATCGACGTCGTCGATCCCGGAACGGGAAACGTTATCAGCAGCGCGA
CGGCCGCGGTTGCCGCCGATATTGATAAGGCCGTCGCAGCCGCTCGGAAGGCTTTCGAAAGCGGCGTGTGGGCCAATATG
CCCGGTCTCGAACGCGGTAAGCTGATCAGCAAGCTCGCGCGCAGGCTTGAAGAGCTTGGCGATGAATTGGCGGAAATCGA
AGCCATCGACTGCGGCAAGCCGCTCGCCTATGCGAAATATGTCGACGTCGGCCTGACCGCCAATATCTATCACTATATGG
CAGGGTGGGCAGGAAAGGCCTCAGGCGAGACTGTTTCGCTCTCGGCTCCAGGCGAGTATCACGCCTTCACGCAGCGTGAG
CCAGTCGGTGTAGTTGCTGCGATCACGCCGTGGAACTTCCCGCTGGTTCTGACCGCCTATAAGCTCGCGCCGCTTCTTGC
TGTCGGCTGCACGTGCGTCGTCAAGCCATCTGAGCTGACGCCTCTGAGCACACTGCGGTTCGCCGAGATCGCGGAAGAGG
TCGGCTTCCCGCCCGGCGTCATCAACGTTGTGACCGGATATGGTTCGCCTGCAGGCTCCGCGCTTGTCGAACATGAAGGT
GTCGACAAGGTCGCCTTCACTGGCTCCGTCGCGACGGGCAGAAAAATCGCGCAAGCCGCAACGGGCAACCTCAAACGTGT
AACGCTAGAACTCGGCGGCAAGTCGCCTATGGTCGTCTTTCCGGATGCCGATCTCGATAAGGCCATTCCGGGTCTGGCCA
GCGCGATCTTCTTCCATCAGGGCCAGGTCTGTACGGCGGGCACTAGGCTTTATGTGCACAAGTCGATCCACGATCGCGTG
CTCGAAGGCATCGCCGAGGAAAGCAAAAAACTGAAGATCGGCCACGGGCTTGAGCCCGACACGACGATGGGCCCGATGAT
CTCTTCGGCGCAGCTTCAGAAGGTCATGGGCTTCCTCGATCAAGGCAAGCAGGAAGGCGCCGAGGTCGTAACAGGCGGAG
AACGCATCGGCAGCGCCGGCTTCTTCATGCAGCCGACAATCCTCGCCAACACGACGGACAGCATGTCGGTCGTGCGCGAG
GAAATTTTCGGGCCGGTGCTGTGCGCTCAGTCGTTCAGCGATGATGAGCTCGACGCGATTGCGGCTAAGGCGAACAACAC
GATCTATGGCCTCGCCGCCAGCGTTTGGACGCGAGACATCTCTGTCGCGCACAAGATGGCGAAACGGATCAAGGCCGGTA
GCGTGTGGATCAATGCGCACAATTTCTACGACCCGGCGCTTCCTTTCGGCGGCTTCAAGCAGTCCGGTTGGGGCCGCGAA
GAAGGCTCCGAAGCCATCCGCACATTCACTGAAGTGAAGTCCGTCTGCGCCGTGCTCTAA

Protein sequence :
MNINVTIPTPSAKTQEFFARKHKLYIDGAWTEGVSGERIDVVDPGTGNVISSATAAVAADIDKAVAAARKAFESGVWANM
PGLERGKLISKLARRLEELGDELAEIEAIDCGKPLAYAKYVDVGLTANIYHYMAGWAGKASGETVSLSAPGEYHAFTQRE
PVGVVAAITPWNFPLVLTAYKLAPLLAVGCTCVVKPSELTPLSTLRFAEIAEEVGFPPGVINVVTGYGSPAGSALVEHEG
VDKVAFTGSVATGRKIAQAATGNLKRVTLELGGKSPMVVFPDADLDKAIPGLASAIFFHQGQVCTAGTRLYVHKSIHDRV
LEGIAEESKKLKIGHGLEPDTTMGPMISSAQLQKVMGFLDQGKQEGAEVVTGGERIGSAGFFMQPTILANTTDSMSVVRE
EIFGPVLCAQSFSDDELDAIAAKANNTIYGLAASVWTRDISVAHKMAKRIKAGSVWINAHNFYDPALPFGGFKQSGWGRE
EGSEAIRTFTEVKSVCAVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-69 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-72 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhaS YP_004674013.1 aldehyde dehydrogenase dhaS VFG0082 Protein 4e-72 42