Gene Information

Name : ureC (HYPMC_1540)
Accession : YP_004675344.1
Strain : Hyphomicrobium sp. MC1
Genome accession: NC_015717
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1453286 - 1454995 bp
Length : 1710 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1400317, 1624427, 2211515, 7721685, 7855593, 7909161, 8318888, 8808930; Product type e : enzyme

DNA sequence :
ATGGCCGCCCGCATTTCTCGCGCCGCTTATGCCGACATGTTCGGCCCCACGACCGGCGACAAGGTTCGCTTGGCCGATAC
GTCGCTCTTCGTCGAGGTCGAGAAGGATTTCACAATCTACGGCGAAGAGGTGAAGTTCGGCGGCGGCAAGGTCATTCGCG
ACGGCATGGGGCAGTCGCAGGTGTCCCGCTCACAGGGCGCCGTCGATACGGTGATCACGAATGCGCTGATCATCGACCAC
TGGGGAATCGTCAAGGCCGATATCGGTCTGAAGGACGGATTGATTGCGGGCATCGGTAAGGCCGGTAATCCTGATGTTCA
GCCGGGCGTCGACATCGTCATCGGGCCGGGTACGGAGGTGATTGCGGGCGAGGGCAAGATCGTTACCGCAGGCGCGTTCG
ATACGCATATCCATTTCATCTGTCCGCAGCAGATCGACGAAGCGCTGGCGGCTGGCATCACGTCGATGCTCGGTGGCGGC
ACGGGGCCCGCGACCGGAACCAATGCCACCACGTGCACGCCGGGCGCTTGGCATCTTCAGCGCATGATCGAAGCGGCCGA
CGCTTTTCCGATGAACCTCGGGTTTGCGGGTAAGGGCAATGCGTCGCTGCCGCAAGGATTGGTGGAGCAGGTCGAAGCCG
GCGCGTGCGCGCTGAAGCTGCATGAAGATTGGGGGACGACGCCCGCAGCCATCGACTGCTGCTTGTCCGTCGCCGACGAG
CACGACGTGCAGGTGATGATCCATTCGGATACGCTCAACGAAAGCGGCTTCGTGGAAGATACGATTGCCGCTTTCAAGGG
GCGCACGATTCATGCGTTTCATACCGAAGGTGCGGGCGGCGGCCATGCACCGGATATCATGAAGGTTGCGGGATACGCGA
ACGTCTTGCCGTCGTCGACCAATCCGACGAAGCCGTTCACCGTCAATACGCTCGACGAGCATCTCGATATGCTGATGGTT
TGCCATCATCTTCATGCGTCCATTCCCGAAGATCTGGCATTTGCGGAAAGCCGGATCAGGAAAGAGACGATTGCAGCGGA
AGATATTCTGCATGATCTCGGCGCGCTCTCGATGATGTCGTCGGATAGCCAAGCCATGGGGCGTATCGGCGAGGTGATCA
TTCGCACGTGGCAAACCGCAGACAAGATGAAGAAGCAGCGTGGCGCGCTTCCCGGCGATGGCGAGAACGATAACCAACGG
GCGAAGCGCTATATCGCCAAGTACACGATCAATCCGGCTATCGCTCACGGTGTATCGCAGCACATCGGCTCGGTCGAGGT
CGGCAAGCTTGCCGACCTGGTGATCTGGTCGCCGGCGTTGTTCGGAGTAAAGCCCAATCTTGTCTTGAAGGCGGGTTCGA
TTGCCGTCGCGGCAATGGGCGATCCGAATGCTTCAATCCCGACGCCGCAGCCTGTCCACTACCGGCCGATGTTTGCATCC
TTCGGCAAATCGCTGACGCGAAGCTCGCTAACGTTCGTTTCGAAAACGTCGCTCGACAAAGGCTTGGCGGATCGACTCAA
GGTCGAAAAGAAGCTCGTTCCGGTTGAGAACGTGCGAGAGGGGATTTCGAAGAAGAGCATGGTTCACAATGGCGCTACTC
CGCATATCGAGATCGACAGCGAAACTTATCGGGTGACGGCAGACGGCGAGCTTCTTGTTTGCGAACCGGCCAAGGAGCTA
CCGATGGCGCAACGCTATTTTCTGTTTTGA

Protein sequence :
MAARISRAAYADMFGPTTGDKVRLADTSLFVEVEKDFTIYGEEVKFGGGKVIRDGMGQSQVSRSQGAVDTVITNALIIDH
WGIVKADIGLKDGLIAGIGKAGNPDVQPGVDIVIGPGTEVIAGEGKIVTAGAFDTHIHFICPQQIDEALAAGITSMLGGG
TGPATGTNATTCTPGAWHLQRMIEAADAFPMNLGFAGKGNASLPQGLVEQVEAGACALKLHEDWGTTPAAIDCCLSVADE
HDVQVMIHSDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMKVAGYANVLPSSTNPTKPFTVNTLDEHLDMLMV
CHHLHASIPEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRIGEVIIRTWQTADKMKKQRGALPGDGENDNQR
AKRYIAKYTINPAIAHGVSQHIGSVEVGKLADLVIWSPALFGVKPNLVLKAGSIAVAAMGDPNASIPTPQPVHYRPMFAS
FGKSLTRSSLTFVSKTSLDKGLADRLKVEKKLVPVENVREGISKKSMVHNGATPHIEIDSETYRVTADGELLVCEPAKEL
PMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-176 67
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-176 67
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-165 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-165 63
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-165 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-165 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004675344.1 urease subunit alpha VFG0270 Protein 2e-155 64