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Name : clpA1 (TPCCA_0549) Accession : YP_004673280.1 Strain : Treponema paraluiscuniculi Cuniculi A Genome accession: NC_015714 Putative virulence/resistance : Virulence Product : S14 family endopeptidase ClpA Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : 3.4.21.92 Position : 590580 - 593024 bp Length : 2445 bp Strand : + Note : ATP-dependent Clp protease, ATP-binding subunit ClpA DNA sequence : GTGTTACAGGACCTATCCGCAAATGCCCGTAAGGTACTGCTCGAGCTCGGTCAGACCGTTGCGCGTGAAGCTCGCGCCTC GCTCCTTCAGCCAGAGCACATTCTGCTCGCCCTCATTCAGCACAAAGTAGGCCGCGGCTACAAGCTCATCGAAAAACTCA TCGAAGATGTCGCTACCGTCCGCCTCATCCTCGAGCAACACGTCCTTACCAATGAGGGAGACGTCGCCAGTCCCCAGGAC CTGCCCGTCTCAGGACGCGTCAAACACTTGCTCGACATCGCAGCAATGGAAGCGCGCTCCCTGCGGTGCGCTTACATCGG TACCGAACACCTCGTTATCGCCTTTGCCCGAGAGGAGCAAAATCCTCTCTTCCAAAGCCTCATCCGAGAAGGACTCTCGC TCGATGACCTGCGAAACGCGAGCATTATATCCTCACCTCATTCTGATACCACCCGCACCCGGCTCGAGCGGAAAGTTGCA AGCGTCCTTGACGAATACGGCACCGACCTTACCGAACGCGCGCGCGCCGGCGCCCTCAATCCGGTCATCGGACGAAACAA AGAAATTACCCGCGTCATTCAAATCCTGTGCCGGAGAGGAAAAAATAACCCGGTGCTCATCGGAGAACCAGGTGTCGGGA AAACTTCCATCGTTGAGGGGCTCGCGTACGCCATCGTTCGGGAGGAGGTCCCGCACATCCTGCTGCACACCCGCGTCGTT TCCCTAGACCTTGCCGCCGTCATAGCAGGAACAAAGTACCGCGGCCAGTTTGAGGAGCGGCTCAAACGCATTATTAAGGA GGTGGAAGAAGCTGAAAAAGTCATCCTTTTCATCGATGAGCTGCACACACTCATCGGAGCAGGAGGCACGCAGGGGTCTT TGGACGCCGCCAACATGCTCAAGCCGGCCCTTGCACGCGGACAAATCCAGTGCATTGGGGCAACAACCCTGGCAGAGTAT CGCCGTTACTTTGAAAAAGACGCAGCTCTCACCCGCCGATTCCGATCGGTGCTCGTGCGTGAACCGAGCTTTGAAGAAAC CTGCACTATTTTACGCAAAATAAAATCACACTACGAACGACATCACCAGGTGATATACCAAAGCGATGCGCTTGAAAAAA TTGTTGAGCTTTCACGGCGCTACATCCCTGAGCGGTTCTTTCCAGATAAGGCAATTGATCTTATGGATGAAGTAGGAGCC ATGAAACGGGTACAACAGCGCGCAGATACGCAGGTATTGCGTTCCTTTTCCATAAGAGTTGCTAATCTTACCACAGATAC TGAGCGCGCCATTGCGCTTGAAGATTGGGCGCGCGCGCGTTCTTTACACACCGATGTAGTGCAGCTGCGCAGACGGCTCC ACGCGCTGAAGGTAGAGTGGAGCGCGCGCGAAGCGCTGTCTATCTTTGCAGAAGATGTTGCACAGGCTGTCTCTCTCATG ACCGATATCCCGGTACATTCGCTCGAAGGGGACGAGCTGTGCCGCTTTACCAATATCGAACGGGATCTTTGTGCCACCGT GCGTGGGCAGCGCGAGGCCATTGCAACGCTCGCGCGCGCCATCGTACGCGCGCGTGTCGGCATCTCTTCAGACACGCGCC CAATTGGCTCCTTCCTGTTTCTTGGACCGACCGGTGTAGGCAAAACGCTTTTGGCAAAGACACTCGCGGAATTTCTTTTC GGTTCAGCAGACGCGCTCATCCGCATTGACATGAGCGACTACATGGAACGCTACAACACCTCACGCCTCATGGGAGCACC GCCTGGATACGTGGGATTTGAAAATGGCGGTCTACTTACCGAGCGCGTACGGCACCGCCCTTTTTCTGTCATCCTTCTGG ATGAAATTGAAAAGGCGCATCCAGATGTCTTCAATGTTCTCCTCCAGGTGTTAGAAGAAGGAGAGCTGCAAGACAACCTG GGGCACACGGTGAACTTCCGCAACACTATCATCATCATGACCAGCAATGCAGGCACACGCGGCCTGGGGGAAAACGTTCC TGGCTTTCAAACCGCACGCGCGCGAAACATCGAGTACCGTCAGCTGCGCGTACAGGCCCTCCGGGAAATAAAACGCATCT TCTCTCCGGAGTTTCTCAATCGCGTTGACGAGTGCGTAGTGTTTGCTCCGCTTGAGCGAGAGACCCTGCAGGAAATTTTA GAATGCGAACTGAAAAAGCTCGCAGAACGCCTACGCGGTAAAGATATTGTGCTGCGCTACAGCGCGGCTGCAAAGGCCTA CTGTCTTGAACACGGCTTTGACCCATTCTTGGGCGCACGCCCCCTGCGCCGCGTATTGCAGCAAGAAATTGAAAATGAGC TTGCGCTGCGCATGATTCACGGAACGTTGCGCGCAGGATCGTGCGTGCACATAGACTCAGACGGCGTGCGCCTCCACCTT TCTACCGAAAAAAGTTACCTGACGCTGCATCCCCAAGAAATATAA Protein sequence : MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV SLDLAAVIAGTKYRGQFEERLKRIIKEVEEAEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA MKRVQQRADTQVLRSFSIRVANLTTDTERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGVRLHL STEKSYLTLHPQEI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 2e-148 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpA1 | YP_004673280.1 | S14 family endopeptidase ClpA | VFG0080 | Protein | 6e-134 | 50 |
| clpA1 | YP_004673280.1 | S14 family endopeptidase ClpA | VFG0079 | Protein | 2e-162 | 44 |
