Gene Information

Name : cadA (SNE_A02980)
Accession : YP_004670666.1
Strain : Simkania negevensis Z
Genome accession: NC_015713
Putative virulence/resistance : Resistance
Product : putative cadmium-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 299771 - 301927 bp
Length : 2157 bp
Strand : +
Note : -

DNA sequence :
ATGGAAAAGAAACTAAGTTTTCATGTCGTTGGCCTAGACTGCGCTGAAGAAATTAAAATCCTGAGAAAAGCAGTTGAGAC
TCGTGAAGGAGTCAAAGACCTGACCTTTGATGTTTTAAATGCGAAAATGACTGTAACATTTGACCCTGGACATGTGACAG
CGCAACATGTGATTGATTGGGTCAAAGGGGCAGGAATGCAAGCTTCGGTGTGGGAAGAGAGAAAAAAAGGCGAACCGAAG
AGTTTTTGGGAAAAACATGGACGCCTCATGATGGCGACCCTTAGTGGCCTTTTTTTGTTTTTGGGATTTTCTCTTCACAT
TTTCTTTCATCCAAATGTGTTAGACATTCTTGGAGAGGTCGATGAAACTACGCACAGTCTTCCGATTATAGTGATTCTCT
TTTATTTGATTTCAATGATCTTTGGAGCTTTTTATTTTGTTCCCAAAGCACTGCTTGCCGTGAAGAGAATGCAGCCAGAC
ATGAATTTGCTTATGGTGATTGCTATGTGTGGGGCGATTGGAATTGGTCAATGGTTTGAAGGGGCAACTGTTGCGTTTCT
TTTTTCTGTTGCCCTTCTTTTGGAACATTGGAGTGTAGGAAGGGCTAGACGCGCGGTGGAAGCTTTGATGGATCTTTCCC
CAACCCAAGCCCGAATGATCACAGATATAGGGCTTAAAGAGGTTCGTGTTGAAGATGTTGAAGTTGGAACGCGCATTTTG
ATCCGTCCAGGAGAAAAAGTTCCATTAGATGCCACGATCGAAAAAGGAAGCACCTCAATCAATCAATCACCCATCACAGG
TGAGTCGATTCCTGTTGCCAAAGAAGAAGGTGATGAAATTTTTGCAGGAACGATTAATGAAGAGGGTGCTATCGAGTGTG
TCACGATAAAAAAAGCGGATGACACCACTCTTGCTCGGATCATCCATTTAGTTGAAGAAGCTCAATCGAGACGGGCGAGT
TCTGAGCAGTGGGTAGAGAAGTTTGCCCGTGTTTATACCCCGATCATGATTATTTTAGCGATTGTCATTGCCCTCATCCC
GCCACTCTTTTTTGGTCTTTCATGGGAAACTTGGTTTTATCGTGCACTTGTTATTTTGGTGATTGCTTGTCCTTGTGCTC
TTGTGATTTCAACGCCTGTCAGTATTGTCTCAGGACTAACTTCTTCGGCGCGCAATGGAGTGCTCATTAAGGGGGGCATG
TATTTAGAGGCTCCTGGCAAACTCGATATCCTGGCGGTTGATAAGACTGGAACATTGACTTATGGCCGACCCAAAGTGCA
AAAGATCATTCCTCTCAATAATCATACAGAAGAAGAGTTACTTTTACGTGCAGCTGCTTTAGAAGCGCCAAGTGAACACC
CTCTTGCTCGAGCGATTCTTAACCTTGCTGAAGAGAGAAACATCCGATTTGAGCGTGCGACAGACTTTCAAATCATTAAA
GGGAAAGGGGCGCAGGGGACCTACAATGGGACTCGTTATTGGATAGGGAGCCACCGCTTCATGCACGAAATGAAGCAAGA
AACAGAAGAAATTCATCGCATGGCCTTGGAGTTAGAAGATGCTGGACATTCGATCGTTGCGATTGGAAATGATAAACACG
TGTGCGGACTCATCAGTGTCGCAGATGAGCCACGTGCAGAGATCCGATCTATTGTTGAAGACATTCGACGTGCAGGAGTC
AAGCATGTGGCGATGCTGACAGGAGATAACGCTCCTGCTGCTGCTGCCATTGCGAAGTTAACGGGAGTTGATTCGGTTCA
ATCAGAACTATTGCCCGAAGATAAAGTCGAAGCAGTGGAAAAATTGAAGGATGGGGGAAAAATCGTTGCAATGATAGGAG
ACGGGGTCAATGATGCCCCAGCAATGGCTGCAGCAGACTTCGGGATTGCGATGGGGGCTATGGGAACTGATGCGGCTATT
GAAACCGCAGATATTGCACTCATGTCCGATGATTTAACGAAAGTGCCATGGCTCATTCGTCATTCGCGGCGTGTCTTACA
TGTGATCAAACAAAACATCACCTTTTCGCTCGCAGTGAAAGTCGTTTTTCTTTCACTTGCAATTGTAGGGATGGCCACCT
TATGGATGGCCATTGCTGCCGACGCTGGTGCCTCACTTCTCGTTGTGTTCAACGGCTTGCGACTTCTTAAGCGTTAA

Protein sequence :
MEKKLSFHVVGLDCAEEIKILRKAVETREGVKDLTFDVLNAKMTVTFDPGHVTAQHVIDWVKGAGMQASVWEERKKGEPK
SFWEKHGRLMMATLSGLFLFLGFSLHIFFHPNVLDILGEVDETTHSLPIIVILFYLISMIFGAFYFVPKALLAVKRMQPD
MNLLMVIAMCGAIGIGQWFEGATVAFLFSVALLLEHWSVGRARRAVEALMDLSPTQARMITDIGLKEVRVEDVEVGTRIL
IRPGEKVPLDATIEKGSTSINQSPITGESIPVAKEEGDEIFAGTINEEGAIECVTIKKADDTTLARIIHLVEEAQSRRAS
SEQWVEKFARVYTPIMIILAIVIALIPPLFFGLSWETWFYRALVILVIACPCALVISTPVSIVSGLTSSARNGVLIKGGM
YLEAPGKLDILAVDKTGTLTYGRPKVQKIIPLNNHTEEELLLRAAALEAPSEHPLARAILNLAEERNIRFERATDFQIIK
GKGAQGTYNGTRYWIGSHRFMHEMKQETEEIHRMALELEDAGHSIVAIGNDKHVCGLISVADEPRAEIRSIVEDIRRAGV
KHVAMLTGDNAPAAAAIAKLTGVDSVQSELLPEDKVEAVEKLKDGGKIVAMIGDGVNDAPAMAAADFGIAMGAMGTDAAI
ETADIALMSDDLTKVPWLIRHSRRVLHVIKQNITFSLAVKVVFLSLAIVGMATLWMAIAADAGASLLVVFNGLRLLKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 6e-118 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 9e-119 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-119 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_004670666.1 putative cadmium-transporting ATPase BAC0298 Protein 2e-107 48