Gene Information

Name : sctO (SNE_A20010)
Accession : YP_004672369.1
Strain : Simkania negevensis Z
Genome accession: NC_015713
Putative virulence/resistance : Virulence
Product : type III secretion chaperone
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2078158 - 2079474 bp
Length : 1317 bp
Strand : +
Note : -

DNA sequence :
ATGGCTGAAGGCCCTGATTTCGATAAGCTTATCGGACAACTAGAAGACATTGAACTGACTACAGTTCATGGACGCATCAC
CGAAATTGTCGGAATGCTCATCAAAGCCGTTGTCCCCAACGTCAAAATGGGTGAGGTTTGCCTCATCAAGCGCGACGGTG
ATCCCCTCATTGCTGAAGTTGTTGGGTTTACAAAAGAAGAAGTCTACCTTTCCCCTCTAGGAGAAATGACAGGCGTCGGT
CCATCATCTGAAGTGATCCCTATGCGCCTTCCTCTTCATATCAAAGTTGGTCCCAATCTTTTAGGACGGGTCTTGGATGG
ACTCGGTCACCCTCTCGATACAGCAGAAAAAGGACCTCTCGAACTTGAGGAGACTTACTCAGTCCTCAACGCTCCCCCTG
ATCCACTAAAACGAGAAATGATCGATAAGCCGATTTCAACTGGAATTCGTGCGATTGATGGAGTTTTGACAGCTGGTCGA
GGACAAAGGATCGGGATTTTTGCGGCTGCTGGAGGCGGTAAGTCGACAACTCTCGGGATGATTGCTCGCTATGCTCAAGC
AGATGTCAACGTTATCACCTTGATTGGAGAGCGGGGACGTGAGGTGCGAGAATTTATTGAACATGACCTCGGTCCCGAAG
GGGTTGCCCGTTCTGTGATTATCGTCTCAACGTCAGATCAAGCAGCGCAACTTCGTTTGAACGCTGCCTATGTGGGAACA
GCTATTGCCGAATACTTCCGCGACCAAGGAAAAACTGTCATCCTGATGATGGACTCTGTGACCCGTTTTGCACGAGCTCT
GCGGGAAATTGGTCTTGCTGCAGGAGAACCTCCTGCGCGCGCTGGTTACACTCCTTCAGTTTTCGCGACACTACCAAAGC
TTCTCGAGCGCTCAGGCAACTCAGACAAAGGTTCGATCACAGCTTTCTACACGATTCTCGTTGCTGGAGATGACATGAAC
GAGCCGGTTGCCGATGAAGTCCGCTCGATCTTGGATGGACATATTATCTTGTCAAGCGAACTTGCTCGTCAATACCACTA
CCCCGCGATCGATATTCTCAGTTCTGCGAGCCGGATTCTTCCGAATGTTACGAGTGAAGAACACCGCAAGCTTATTGGTC
AGATCCGAGAAGTTCTTGCGAACTACAAGAAGAACGAGCTTCTTATTCGGATTGGAGAATACAAGCCCGGCTCAGATAAG
CAAGCCGATTTTGCCATCAAGTATGTGGATAAGGTAAACCGCTTCCTCAAACAAAAAGTCGATGAAAAGTGTACCTTTCA
AGAAACTCTCGAGCAACTCCAAGCCTTATTTAGGTAA

Protein sequence :
MAEGPDFDKLIGQLEDIELTTVHGRITEIVGMLIKAVVPNVKMGEVCLIKRDGDPLIAEVVGFTKEEVYLSPLGEMTGVG
PSSEVIPMRLPLHIKVGPNLLGRVLDGLGHPLDTAEKGPLELEETYSVLNAPPDPLKREMIDKPISTGIRAIDGVLTAGR
GQRIGIFAAAGGGKSTTLGMIARYAQADVNVITLIGERGREVREFIEHDLGPEGVARSVIIVSTSDQAAQLRLNAAYVGT
AIAEYFRDQGKTVILMMDSVTRFARALREIGLAAGEPPARAGYTPSVFATLPKLLERSGNSDKGSITAFYTILVAGDDMN
EPVADEVRSILDGHIILSSELARQYHYPAIDILSSASRILPNVTSEEHRKLIGQIREVLANYKKNELLIRIGEYKPGSDK
QADFAIKYVDKVNRFLKQKVDEKCTFQETLEQLQALFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-110 55
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-105 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-105 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-106 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-104 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-104 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 6e-104 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-104 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-104 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-104 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-94 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-94 51
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-94 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-94 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-94 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-92 51
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-92 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-91 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-91 50
escN AAK26715.1 EscN Virulence LEE Protein 2e-90 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 6e-91 50
escN AAL57542.1 EscN Virulence LEE Protein 2e-90 50
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-89 50
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-82 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-90 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-90 49
escN AAC38383.1 EscN Virulence LEE Protein 2e-90 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 8e-91 49
escN AAC31513.1 L0034 Virulence LEE Protein 1e-90 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-90 49
escN CAI43874.1 EscN protein Virulence LEE Protein 6e-91 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-90 49
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-91 49
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-79 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-84 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-85 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-85 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-88 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-93 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 6e-88 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-88 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-78 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-78 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-73 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-71 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-77 45
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-71 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-71 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-71 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-71 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sctO YP_004672369.1 type III secretion chaperone VFG2144 Protein 4e-157 70
sctO YP_004672369.1 type III secretion chaperone VFG0048 Protein 4e-119 57
sctO YP_004672369.1 type III secretion chaperone VFG0390 Protein 1e-111 56
sctO YP_004672369.1 type III secretion chaperone VFG0192 Protein 9e-113 55
sctO YP_004672369.1 type III secretion chaperone VFG0515 Protein 2e-94 51
sctO YP_004672369.1 type III secretion chaperone VFG0812 Protein 8e-91 49
sctO YP_004672369.1 type III secretion chaperone VFG0730 Protein 1e-90 49
sctO YP_004672369.1 type III secretion chaperone VFG2499 Protein 6e-85 47
sctO YP_004672369.1 type III secretion chaperone VFG1254 Protein 3e-89 46
sctO YP_004672369.1 type III secretion chaperone VFG2331 Protein 9e-84 46
sctO YP_004672369.1 type III secretion chaperone VFG0555 Protein 2e-71 44
sctO YP_004672369.1 type III secretion chaperone VFG2459 Protein 1e-76 44
sctO YP_004672369.1 type III secretion chaperone VFG1778 Protein 3e-75 44
sctO YP_004672369.1 type III secretion chaperone VFG1008 Protein 1e-71 43