Gene Information

Name : LILAB_26315 (LILAB_26315)
Accession : YP_004668233.1
Strain : Myxococcus fulvus HW-1
Genome accession: NC_015711
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 6323734 - 6325380 bp
Length : 1647 bp
Strand : -
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
GTGACGTCCACCACGCTCCCGGGCTGCCCCACCTGGCCGGAGGACTACGCCGCCCGCTACCGCGCCGCCGGCTACTGGCG
CGGGGAGACCTTCGGTCAGCTCCTCCACGAGCGCGCGCGCACGCACGGCGAGCGGACCGCGCTGGTGGCCGGTGAGCGCC
GCCTCACCTACGCGGCGCTGGACGCCCGCGTCAGCCAGCTCGCCGCCGGCTTCCACGCGCTGGGCATCCAGGCGAAGGAC
CGCGTCGTGGTGCAGCTCCCCAACGTGGCGGAGTTCTTCGAGGTCGTCTTCGCCCTTTTCCGGCTGGGCGCGCTGCCGGT
GTTCGCGCTGCCCGCGCACCGCGCGTCGGAGATTGGCTACTTCTGCGCCTTCACCGAAGCGGTGGCCTACGTCATCGCGG
ACAAGCAGGCCGGCTTCGACTACCGCGCGCTGGCCGAGCAGGTGCGCGCCAACTGCCCCACGCTGAAGCACGTCATCGTC
GCCGGAGACGCGGGCGCCTTCACGCCGCTGAGCAGCCTGTTCGCCGCGCCCACCGAGCTGCCGCCGGGGCCCGCCCCCAG
CGACGTGGCCTTCTTCCAGCTCTCCGGCGGGAGCACGGGCGTGCCCAAGCTCATCCCGCGCACGCACGACGACTACATCT
ACAGCCTGCGCGGCAGCGTGGACATCTGCCAGGTCGACGAGGACAGCGTGTACCTGTGCGCGCTGCCCGCGGCGCACAAC
TTCCCGCTCAGCTCGCCGGGGGTGCTCGGCACCTTCTACGCGGGGGGCACGGCGGTGCTGGCGCCCAACCCCAGCCCGGA
CACGGTGTTCCCGCTCATCGAGCGCGAGCGCGTCACCCTCACCGCGGTGGTGCCGCCGCTGGCCATGGTCTGGATGGACG
CGGCCAAGGCGCGCCAGCACCAGCTCGCCAGCCTGAAGGTGCTCCAGGTCGGTGGCGCCCGACTCAGCGACGAGGCGGCC
CGGCGCGTGAAGCCGACGCTGGGCTGCACGCTGCAGCAGGTGTTCGGCATGGCCGAGGGCCTGGTCAACTACACGCGCCT
GGACGACCCCGAGGACGTCATCGTCAGCACCCAGGGCCGCCCCATCTCCCCGGACGATGAAATCCGGGTGGTGGACGAGG
ACGGCGAGGACGTGGCGCCCGGCGAGACGGGCCAGCTCCTCACGCGCGGCCCCTACACCATCCGCGGCTACTACAAGGCG
GAGGCCCACAACGCGAAGGCCTTCACCGCGGACGGCTTCTACCACACGGGTGACGTGGTCCGCGTGACGCCCCAGGGCTA
CCTGGTGGTGGAGGGCCGCGCCAAGGATCAGATCAACCGGGGCGGCGACAAGGTCGCGGCCGAGGAGGTGGAGAACCACC
TGCTGGCCCACCCCGACGTGCACGACGCCGCGGTGGTCGCCGTGCCGGATGCGTTCCTGGGCGAGCGCACCTGCGCCTTC
GTCATCGCGCGAGGCACGCCGCCCGCGCCCAAGGTCCTCACGGCCTTCCTGCGCCAGCGCGGCCTGGCCGCCTTCAAGAT
CCCCGACCGCGTCGAGTTCGTCGAGACGTTCCCGAAGACGGGCGTCGGCAAGGTCAGCAAGAAGGCGCTGCGCGACGTGC
TCGCCAACGCCCCCTCCTCCACCCCGGTTTCGCGCGCCACGCGCTGA

Protein sequence : 
MTSTTLPGCPTWPEDYAARYRAAGYWRGETFGQLLHERARTHGERTALVAGERRLTYAALDARVSQLAAGFHALGIQAKD
RVVVQLPNVAEFFEVVFALFRLGALPVFALPAHRASEIGYFCAFTEAVAYVIADKQAGFDYRALAEQVRANCPTLKHVIV
AGDAGAFTPLSSLFAAPTELPPGPAPSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVDICQVDEDSVYLCALPAAHN
FPLSSPGVLGTFYAGGTAVLAPNPSPDTVFPLIERERVTLTAVVPPLAMVWMDAAKARQHQLASLKVLQVGGARLSDEAA
RRVKPTLGCTLQQVFGMAEGLVNYTRLDDPEDVIVSTQGRPISPDDEIRVVDEDGEDVAPGETGQLLTRGPYTIRGYYKA
EAHNAKAFTADGFYHTGDVVRVTPQGYLVVEGRAKDQINRGGDKVAAEEVENHLLAHPDVHDAAVVAVPDAFLGERTCAF
VIARGTPPAPKVLTAFLRQRGLAAFKIPDRVEFVETFPKTGVGKVSKKALRDVLANAPSSTPVSRATR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-113 52
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-113 52
ybtE CAA21394.1 - Virulence HPI Protein 5e-114 52
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 4e-114 52
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 6e-114 52
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-114 52
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 5e-114 52
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-114 52
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-114 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LILAB_26315 YP_004668233.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-128 54
LILAB_26315 YP_004668233.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-108 49
LILAB_26315 YP_004668233.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-107 47