Gene Information

Name : LILAB_20505 (LILAB_20505)
Accession : YP_004667079.1
Strain : Myxococcus fulvus HW-1
Genome accession: NC_015711
Putative virulence/resistance : Resistance
Product : Bcr/CflA family protein drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 4838585 - 4839769 bp
Length : 1185 bp
Strand : -
Note : COG0477 Permeases of the major facilitator superfamily

DNA sequence :
TTGCTGATGGCGCCCTTCGACCTCCTGGCCTCGTTGGCCATGGACATCTACCTGCCTGCCGTTCCGACGCTGCCTGGCGT
CCTCGACACGTCCCCCGCCATCGTCCAGCTCACCCTGAGCCTGTACATGGCGGTGCTCGGGCTCGGGCAGATGGTGTTCG
GCCCCATCTCCGACCGTATCGGCCGGCGCCGCGTGCTGTTGACCGGCGCCCTCCTGTTCGCCGTCACGTCCTTCCAGCTC
GCGCTCACCTCGGATGCCGCGCTGTTCGTGGGCCTCCGGCTCCTCCAGGCCATGGGAGCGTCCGCGGCGCTCGTCGCCAC
GTTCGCGACGGTCCGCGATGTCTATGCGGAGCGCCCCGAGAGCGCCGTCATCTACAGCCTGTTCAGCACCCTGCTGGCCT
TCGTCCCGGCGCTCGGCCCCATCGCGGGGGCGCTGCTCATGCAACGCTTCGGATGGCGAGCCATCTTCATCACGCTCGGC
CTCCTGTCGGCGGCGGCGCTGCTGCGAGCCTTGCCCCGGTGGCATGAAACGCGCCCGCCCCAGGGGCTCCAACGCAGGCC
CGCGCTCCGGCACCTCCTGAGCAGCGCCCCGTTCTGGACGTACACCCTGGGCTTCAGCGCGGCCATGGGCTCGTTCTTCG
TGTTCTTCTCCACCGCGCCCCGGGTGCTCATCGGCCAGGTGGGGCTCTCTGAGCTCGAGTTCAGCCTCGCCTTCGCCACC
GCCGCGCTCGCGATGATTCTGACGACCCGCTTCGCGAAGCGCTTCGTGGCGGAGTGGGGGCTGGCGGGAAGCCTCACCCG
AGGCATGGGCCTGCTGCTGCTCGGCGCGGCGCTCCTGACGGCCGGACAGCTCCTGACGGCGCCGTCCTTCTGGACCTTCG
TCGCGCCCATGTGGCTCATCGCCGCGGGCATCGTGTTCTCCGTCTCCGTCACCGCGAATGGCGCACTCCAGGCCTTTGGC
GATGTGGCGGGCACGGCCGTGGCGCTCTACTTCTGCATCCAGAGCCTCATCGTCGGCCTCCTGGGCACGCTGATGGTCGT
CGTGCTGAACGGCGACACGGCGTGGCCCCTGGTGGGATACGCGACGCTGATGGCCCTGGTGACGTTGACCGCCCTCCAGC
GCCTCCGGAGCCGCCCAGGCGCCCAGCAGGAACCCACGCCCGCCACGGACGCTGGCGCCACCTAG

Protein sequence :
MLMAPFDLLASLAMDIYLPAVPTLPGVLDTSPAIVQLTLSLYMAVLGLGQMVFGPISDRIGRRRVLLTGALLFAVTSFQL
ALTSDAALFVGLRLLQAMGASAALVATFATVRDVYAERPESAVIYSLFSTLLAFVPALGPIAGALLMQRFGWRAIFITLG
LLSAAALLRALPRWHETRPPQGLQRRPALRHLLSSAPFWTYTLGFSAAMGSFFVFFSTAPRVLIGQVGLSELEFSLAFAT
AALAMILTTRFAKRFVAEWGLAGSLTRGMGLLLLGAALLTAGQLLTAPSFWTFVAPMWLIAAGIVFSVSVTANGALQAFG
DVAGTAVALYFCIQSLIVGLLGTLMVVVLNGDTAWPLVGYATLMALVTLTALQRLRSRPGAQQEPTPATDAGAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 2e-92 66
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 4e-93 65
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 4e-93 65
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-94 65
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-94 65
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-94 65
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 7e-71 49
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 8e-71 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LILAB_20505 YP_004667079.1 Bcr/CflA family protein drug resistance transporter AF156486.gene.p01 Protein 2e-69 52
LILAB_20505 YP_004667079.1 Bcr/CflA family protein drug resistance transporter DQ984668.gene.p01 Protein 4e-71 49
LILAB_20505 YP_004667079.1 Bcr/CflA family protein drug resistance transporter AF294653.1.gene4.p01 Protein 4e-71 49
LILAB_20505 YP_004667079.1 Bcr/CflA family protein drug resistance transporter DQ522237.1.gene4.p01 Protein 4e-71 49
LILAB_20505 YP_004667079.1 Bcr/CflA family protein drug resistance transporter NC_010410.6003586.p0 Protein 4e-71 49