Gene Information

Name : Theth_0629 (Theth_0629)
Accession : YP_004659812.1
Strain : Thermotoga thermarum DSM 5069
Genome accession: NC_015707
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 635012 - 637459 bp
Length : 2448 bp
Strand : +
Note : COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR003593:IPR004176:IPR003959:IPR001943:IPR013093:IPR0194 89:IPR018368:IPR001270; KEGG: tle:Tlet_0789 ATPase; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein;

DNA sequence :
ATGTTTGACAAGTTTTCCGAAAAGTCCGCGCAGGTTTTCGTTGAGGCGCAAAACGAAGCAAAAGAAATGGGACATTCTTA
TGTGGGTACAGAGCATATTTTGCTTGCCATATTGAAGCAGGAATCCGCCTTGTCAGAAAGCCTTGCGGAAATGGGTATAA
CTTATTCTAGAGCAAAGAATGAAGTTATTTCCATAGTTGGTATGGGAATGCGTGGCATGACAAGCTCGCCACAGATGACT
CCTCGTGCAAAAAGGATCATTGAGCTAGCTTACGAGGAGGCAAAGTATCTTGGTAGCGAGAAAATACAACCTGAGCACCT
TCTGCTTGGAATCATAAGAGAAGGAGAAGGGATAGCAGTTCACGTTCTTAGAAAAATGGGAGCAGACCTCGGAGCTCTTA
GACGCATAATCATTGAAAACAGCTCGTTTAGAATAAACGACTTTGAATCCGACAAAGGTTTGGAAAACGCTTCGGTGAGG
CAGCTTGAAGGATTTGGAATAGATTTGACCGCTCTTGCGATGAAAAATCAGCTTGATCCAGTCATAGGTAGGGATGAGGA
AATAGAAAGAGTAATGCAAGTTTTGGTAAGAAGAAAGAAAAACAACCCTGTTCTGATCGGTGAGCCCGGTATAGGAAAAA
CTGCGATAGTTGAAGGTTTGGCTCAAAGAATTGTGGCAGGCGAAGTTCCAGAACCATTGAAGAGAAAAACCATCTTTGCT
CTGGATGTTGCAGCTTTGGTTGCCGGTACCAAGTATCGTGGAGAGTTCGAAAAAAGGATGAAAAAACTTTTGCAAGTTGT
TACCAGAGACCCCAATATAATTCTCTTCATAGATGAAATTCACACCATAGTTGGTGCCGGGTCGGCGGAAGGTGCTATAG
ATGCCGCAAACATCCTTAAGCCAGCTTTGGCTCGCGGTGAGGTTAGATGCATAGGTGCTACCACACCAGACGAGTATCGA
AAGTACATAGAAAAGGATGCGGCTTTGGAAAGAAGGTTCCAGAAAATTTACGTCAGAGAACCTACTCCTGAGGAAACTTT
GGAAATCCTCAAAGGGTTGAGATCGAAGTACGAAGCTCATCACAGAGTCAGGTACAGCGATATGGCACTTGAAGCAGCTG
TTTATCTTTCAAAACGTTATATTACCGATCACTTCTTGCCTGATAAAGCGATAGACGTCATAGACGAGGCTGGTGCAAGG
GCTCGTTTGAGAAGTTTCGTGCTCCCACCTGAACTTCGCGAGCTTAAAAAACAACTTGATCAAATAAAGGCTGAAAAAGA
ACTTGCGGTTTTGAACCAAGATTATGAAAAAGCTGCAGAATTGAAAGAGCGTGAGAGAATTTTGACGCAGACTTACAACG
AGCAGTACGAACAATGGAGAAAGAGCGTGGAAACGAAAATAATAGACGTAGGAGTTGATGACGTTGCAGAGGTTGTTTCA
AGCTGGACGGGTATACCCTTGACGAAACTTGAAGAAAGCGAAAGCGTAAAACTCCTTAACCTTGAAAAAGTTCTCCATGA
AAGAATAGTTGGTCAAGACGAAGCGATAAAAGCCGTTGCAAGGGCTATCAGAAGGGCAAGAAGCGGTTTGAAAGATCCAA
GAAGACCTATTGGAGTGTTCTTGTTCCTTGGCCCTACTGGTGTTGGTAAAACGGAGCTCACAAAAGTTCTTGCCACTCAT
CTATTTGGTGATGAAAAAGCTCTAATAAGATTTGACATGAGCGAATATATGGAAAGATTCTCAGTTTCTCGTTTGATCGG
AGCGCCTCCAGGATACGTTGGTTACGAAGAAGGTGGAACGTTGACGGAAAAAGTGCGAAGAAGACCGTTCTCCGTGATAC
TTTTTGACGAAATTGAAAAAGCTCACCCGGATGTGTTCAACATATTGCTTCAGATAATGGACGAAGGAAGGCTGACGGAT
TCACAAGGTAGGGAAGTTGACTTCAGGAACACGATAATAGTCATGACGAGCAACATTGGAGGTACTTTGATAAACAAGTC
GAAGCGAACGCTTGGATTTGTATCGGAAGATAACTTCCAGCAAGAATACGAGGAAATCAAGCAGTTGGTCCTTGAAGAGG
TCAAGAAAACCTTTAGACCAGAGTTTCTCAACCGCATTGACGAAATAATAGTCTTCCACCCGTTGACAAGAGAACACATA
GAAAAGATTGTCGATATCTTGGTTTCAGATTTGCGTGAGAGGTTGAAAGAGAAGAATCTGAGCTTGGTTTTGACAAAAGA
AGCCAAGGATTTGTTGATCGAAAAAGGTTTCGATCCAGTGTACGGCGCCAGACCACTTAAGAGAGCAATACAGCAACTGC
TCGAAGATCCTTTAGCTGAGGAAATTTTGAGAGGTAAGTTCAATCCAGGCGATACGATTGTTTGTAAGGCTTCGGCAGGT
AGGATAATATTCACAAAAAGAAAACAAAGAGCGGGAGCTTTGAGCTAA

Protein sequence :
MFDKFSEKSAQVFVEAQNEAKEMGHSYVGTEHILLAILKQESALSESLAEMGITYSRAKNEVISIVGMGMRGMTSSPQMT
PRAKRIIELAYEEAKYLGSEKIQPEHLLLGIIREGEGIAVHVLRKMGADLGALRRIIIENSSFRINDFESDKGLENASVR
QLEGFGIDLTALAMKNQLDPVIGRDEEIERVMQVLVRRKKNNPVLIGEPGIGKTAIVEGLAQRIVAGEVPEPLKRKTIFA
LDVAALVAGTKYRGEFEKRMKKLLQVVTRDPNIILFIDEIHTIVGAGSAEGAIDAANILKPALARGEVRCIGATTPDEYR
KYIEKDAALERRFQKIYVREPTPEETLEILKGLRSKYEAHHRVRYSDMALEAAVYLSKRYITDHFLPDKAIDVIDEAGAR
ARLRSFVLPPELRELKKQLDQIKAEKELAVLNQDYEKAAELKERERILTQTYNEQYEQWRKSVETKIIDVGVDDVAEVVS
SWTGIPLTKLEESESVKLLNLEKVLHERIVGQDEAIKAVARAIRRARSGLKDPRRPIGVFLFLGPTGVGKTELTKVLATH
LFGDEKALIRFDMSEYMERFSVSRLIGAPPGYVGYEEGGTLTEKVRRRPFSVILFDEIEKAHPDVFNILLQIMDEGRLTD
SQGREVDFRNTIIVMTSNIGGTLINKSKRTLGFVSEDNFQQEYEEIKQLVLEEVKKTFRPEFLNRIDEIIVFHPLTREHI
EKIVDILVSDLRERLKEKNLSLVLTKEAKDLLIEKGFDPVYGARPLKRAIQQLLEDPLAEEILRGKFNPGDTIVCKASAG
RIIFTKRKQRAGALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theth_0629 YP_004659812.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 0.0 55
Theth_0629 YP_004659812.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 1e-148 52