Gene Information

Name : Theth_0393 (Theth_0393)
Accession : YP_004659584.1
Strain : Thermotoga thermarum DSM 5069
Genome accession: NC_015707
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 389687 - 390955 bp
Length : 1269 bp
Strand : -
Note : COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912:IPR016204:IPR019811; KEGG: tmt:Tmath_2179 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein;

DNA sequence :
ATGATAAAAGTTGGAATACTTGGCCTTGGTACTGTTGGTTCTGGTGTTGTGGAACTTCTTGAAAAGGACCGTTCTATCAT
AACTAAAAAACTTGGCAAAGAAATTGTGGTGGAAAAAATACTAGTTCGGAATCCTTCCAAACAAAGGCCAGATTATGCAA
AAGGAAAAATAGTTTTTAACGCTGACGAGATTTTGAACGATCCAGAAATCAAAGTTGTTGTGGAACTAATTGGTGGAGAA
GAACCAGCTAAAACTTATATTGAAAAGGCCTTAAAGAAAGGAAAGCATGTTATCACAGCAAACAAAGAAGTTGTTTCAAA
ATATGGAAAAGAACTTCTTGAGATTGCCAAACAGCAGAACGTGGCTTTTCTTTTTGAAGCAAGCGTTGCAGGTGGAATAC
CGATAATACGTCCAATGAAGCGTTGTCTTGCCGCCAATAGAATCATCAAAATTCAAGGCATACTCAATGGAACCACCAAT
TACATTTTAACCCAAATGCAAGAAAACAAAAAAACTTTTCAAGAGGCTCTCTTTGAAGCACAAAAACTCGGGTATGCTGA
GAGTAATCCCTCTGCCGATGTGAAGGGTTTTGATGCTGCAAGGAAAATATCCATACTCTCTTCGATAGCTTTCAACACAT
GGATAACGCCAGATAAGGTTTACACAGAAGGTATTGAAAAAATTGGAATTGAAGATATAAAGTATGCCGCAGAGCTTGGA
TATGTGATAAAACTAATTGCTTCAGCTCGAAAGGTTTCAGATAATGATATCGAAATCATGGTTTGCCCAACCATGATCAA
TCAAAACCATCCTTTAAGTTCTGTTCGAGGAGTCTACAACGCGGTACTTGTAGAAGGAGATGCCGTAGGCGAGGTGATGT
TTTTTGGTCAAGGAGCTGGAAAAATGGCAACGGCGAGTGCCGTGGTGGCCGACATTATGGAAGCAGCCAGTGGAAAAAAT
TGCGAATACAACTTTGTCAATTGTGATATAAACGTCGTCGACGTTTGGACATGTAAAAGTGATTTCTACATCCGCCTTAA
AGCGATTGACAAGTCAGGAGTTCTTGCAAAAATCAGTGCTGTTTTTGGAAAGAACGACATAAGTATTCATACCGTTGTTC
AAAAGGATGTCAAAAATGAGATGGCAGAAATAGTTATATTAACTCATAAAACAACTTTTGGGAACCTTAAGAACGCTGTT
TTGGAAATTGAAAAACTCGATGTGGTTAAAAGTGTTGATTCTGTAATAAAAGTTGAAGGGGGCAGTTAA

Protein sequence :
MIKVGILGLGTVGSGVVELLEKDRSIITKKLGKEIVVEKILVRNPSKQRPDYAKGKIVFNADEILNDPEIKVVVELIGGE
EPAKTYIEKALKKGKHVITANKEVVSKYGKELLEIAKQQNVAFLFEASVAGGIPIIRPMKRCLAANRIIKIQGILNGTTN
YILTQMQENKKTFQEALFEAQKLGYAESNPSADVKGFDAARKISILSSIAFNTWITPDKVYTEGIEKIGIEDIKYAAELG
YVIKLIASARKVSDNDIEIMVCPTMINQNHPLSSVRGVYNAVLVEGDAVGEVMFFGQGAGKMATASAVVADIMEAASGKN
CEYNFVNCDINVVDVWTCKSDFYIRLKAIDKSGVLAKISAVFGKNDISIHTVVQKDVKNEMAEIVILTHKTTFGNLKNAV
LEIEKLDVVKSVDSVIKVEGGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 7e-64 42
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 7e-64 42