Gene Information

Name : Theth_0389 (Theth_0389)
Accession : YP_004659580.1
Strain : Thermotoga thermarum DSM 5069
Genome accession: NC_015707
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 384607 - 386091 bp
Length : 1485 bp
Strand : +
Note : COGs: COG1190 Lysyl-tRNA synthetase (class II); InterPro IPR004365:IPR004364:IPR002313:IPR006195:IPR018149; KEGG: tle:Tlet_0518 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl

DNA sequence :
GTGCTAGACGAAGTTCGAAAACAAAGATCTGACGAAGTAAAAAGTCTTCGAGAGCTTGGAATAGAACCTTATCCTTACAA
GTTTGAAAAAACCCACTCAGCGCAGGATGTAAAAAAGCAGTTTGATCATGTAAAACCTGGAGAGCTGGCAGAGGGATCTG
AGGTTTCGATAGCCGGTAGGATAATGTCCATCAGAAACCACGGAAAATCGTCTTTTTTCACGCTCAGAGATTTCACTGGT
AGAATTCAGGCTTACATAAGGAGCAACGATGTTGGAGTAGATATGTACAAAATTTTTGAAGAGTACGTAAAGATCGGAGA
CATCTTAGGAGTAAAGGGTCCGGTTTTTCGGAGTAAAACAAGTGAAATAACTGTTCTTGTGAAGGAGTTTAAGATACTTT
GCAAAAGTCGAAGACCTCTGCCTGAAAAATGGCACGGATTGAAAGATAAGGAAATAGCTTACAGGCAAAGGTACGTCGAT
ATGATAGCCAACGATGAGACGCTCGCTAGGTTCAAAATAAGGTACGAAGCCATCAGATTCATTAGGGAATTTTTGACAAA
ACGTGGTTTTGTGGAAGTTGAAACACCCATTTTGAATTACATTCCAAGTGGTGCAAGTGCAAAGCCTTTTATCACTCGTT
CTGAAGCTTTGGATTGTGAGTTGTACCTTCGCATAGCTCCAGAGCTTTATTTGAAGCGCTACATAGTTGGTGGATTTGAA
AAGGTTTTTGAACTTGGGAAAAACTTCAGAAACGAAGGCATTTCCTACAAACATAGTCCAGAATTTACTTCGATAGAGAT
ATACCAAGCTTATGCGGATTACCATGATATGATGGAATTAACTGAATCCATGATTTCAGAGCTTGTTTACCACCTGTTTG
GTAAGTACACAGTGACTTATCAGGGAATAGAGCTGGACTTCAGACCACCTTGGAGAAGGATAAGGATGAGAGATTTCATA
AAATCCAAGCTCAACGTTGACATACTTGAAGATTCCGATGAGACAATGAGGAAAGTATTACAAAACCACGGTGTGGATAC
TTCAGGTCTTTCAAGGGCAAAAATGATCGAAAAGCTTTGGGATCTTGTTGAAAGCGAAGTTGTTCAGCCTACTTTCGTCA
TGGATTATCCTGTTGAAATTTCGCCTTTGGCAAAACGTCACAGGGAAGATCCCAGACTAACCGAAAGGTTTGAACCAATA
GTTTGCGGTATGGAGCTTGGGAATGCCTTTAGTGAGTTAAACGATCCTGACGATCAATTTCAAAGATTTTTAGAGCAAGC
AAAGTTAAGGGAAGCAGGAGACGAAGAAGCGCACAGAATGGATTTGGATTTCATAAGAGCCCTGGAATACGGAATGCCCC
CAACAGGTGGTCTTGGGATTGGTATCGACAGATTGATGATGATTTTAACTGATTCACCTTCAATACGCGATGTAATTGCA
TTTCCTCTTGTCAGCTTTAAGGATAAATATGAAGACGAATTTTGA

Protein sequence :
MLDEVRKQRSDEVKSLRELGIEPYPYKFEKTHSAQDVKKQFDHVKPGELAEGSEVSIAGRIMSIRNHGKSSFFTLRDFTG
RIQAYIRSNDVGVDMYKIFEEYVKIGDILGVKGPVFRSKTSEITVLVKEFKILCKSRRPLPEKWHGLKDKEIAYRQRYVD
MIANDETLARFKIRYEAIRFIREFLTKRGFVEVETPILNYIPSGASAKPFITRSEALDCELYLRIAPELYLKRYIVGGFE
KVFELGKNFRNEGISYKHSPEFTSIEIYQAYADYHDMMELTESMISELVYHLFGKYTVTYQGIELDFRPPWRRIRMRDFI
KSKLNVDILEDSDETMRKVLQNHGVDTSGLSRAKMIEKLWDLVESEVVQPTFVMDYPVEISPLAKRHREDPRLTERFEPI
VCGMELGNAFSELNDPDDQFQRFLEQAKLREAGDEEAHRMDLDFIRALEYGMPPTGGLGIGIDRLMMILTDSPSIRDVIA
FPLVSFKDKYEDEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-92 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theth_0389 YP_004659580.1 lysyl-tRNA synthetase VFG1668 Protein 2e-92 45