Gene Information

Name : Theth_1720 (Theth_1720)
Accession : YP_004660861.1
Strain : Thermotoga thermarum DSM 5069
Genome accession: NC_015707
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1741678 - 1743192 bp
Length : 1515 bp
Strand : -
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterPro IPR017926:IPR004739:IPR001674:IPR000991; KEGG: tle:Tlet_0227 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase, large subunit; TIGRFAM: GMP

DNA sequence :
ATGAAAGTACTTGTGGTTGACTATGGTTCTCAATACACCCAGTTGATAGCACGAGTCGTCAGAGAACTTGGTTATTATAG
CCAAGTTGTGCAATACGATGAACAAGTCGATCTTGAAGATGTACAAGCCGTGATACTTTCTGGTGGCCCTGCCAGCGTTT
ACGAAGAAGATGCACCAAAACTTCCGGATTGGTTTGAAAAATACGAAGGAAAAGTTCTTGGAATATGCTATGGAATGCAA
CTTGTAGCACATTCACTTGGTGGAAAGGTTGAGCCTGGAGAAAAAGCTGAATACGGTAGGACAACGATAAGACTCATCGA
AGATGACCCGATCTTTTTTGGGGTGGAAAAAGAAACCACCGTTTGGATGAGCCATGGAGACCACGTCAAAGTTCTACCAA
AAGGTTTCAAAGTTCTGGCAAAATCGACGGATGAAATAATCGCAGCCGCGACCGACGGAAAAAGGTATTGGCTTTTGCAG
TTTCATCCAGAGGTACGACACACCTTGCGAGGAAGAGAAATTCTTCACAACTTTCTTTCAAAGATTTGCAATCTTAAACC
AAATTGGAACTTGGAGGATTTTGTCAGCAAAAAGATCGAAGAGCTCAGGGAAACTCTGGCTGGAAAAAAAGTCATAGCAG
CGCTTTCTGGAGGGGTGGATTCTTCTGTAGCTTGCGTTTTAACCCACAAAGCGATAGGGGAAAATTTGCTCAACGTTTTC
GTCGATCATGGGTTTTTGAGAAAGGGTGAAGAAAACGAGGTTCCAAAGGTTTTCAAAGAAATGCTTGGGCTGAATTTGGT
GAAAATAAACGCAAGAAAAAGATTTTTGGAAAAGCTTCGTGGAGTAAGCGATCCTGAAAGGAAAAGAAAAATAATAGGGG
AAGAATTCATAAGAGTTTTCGAAAAGCAAGCTCAACAGCATGGTGCGACACACTTAGTTCAGGGAACGATCTACTCGGAT
GTGATAGAGAGCGCAAAATCTGGTAAGAAAACGGCTGCCATCAAAAGTCATCACAACGTTGGTGGACTTCCTGAGAGAAT
GAATCTACAGATCGTTGAACCTCTGAGAAATCTTTTCAAAGATGAGGTAAGGTTGGTTGGAGAAATCCTTGGGATACCAA
GACAAATACTTTACCGCCATCCGTTCCCTGGACCAGGTCTTGCGGTGAGAATCTTAGGAGAGGTCACTGAAGAAAAGCTT
GAAATCTTAAAGGAAGCAGACAGAATTTTCATAGAAACTTTAAAGGAAACTGGCTGGTACGAAAAAGTCTGGCAGGCTTT
CTGTGTGCTTCTGCCGGTTAGATCTGTTGGAGTCAGGGGTGACAAAAGAGCCTACGACTATGTTCTTGCCCTCAGAGCCG
TCGATAGCACGGAAGGCATGACCGCCGATTGGTCGAAAATTCCCCATGAGGTACTAGATCTTGCCGCAAGAAGGATTTTA
AACAGCGTCAAAGGAATAGGGAGGGTAGTGTACGACATCAGCTCAAAGCCACCAGCGACTATCGAATGGGAATAG

Protein sequence :
MKVLVVDYGSQYTQLIARVVRELGYYSQVVQYDEQVDLEDVQAVILSGGPASVYEEDAPKLPDWFEKYEGKVLGICYGMQ
LVAHSLGGKVEPGEKAEYGRTTIRLIEDDPIFFGVEKETTVWMSHGDHVKVLPKGFKVLAKSTDEIIAAATDGKRYWLLQ
FHPEVRHTLRGREILHNFLSKICNLKPNWNLEDFVSKKIEELRETLAGKKVIAALSGGVDSSVACVLTHKAIGENLLNVF
VDHGFLRKGEENEVPKVFKEMLGLNLVKINARKRFLEKLRGVSDPERKRKIIGEEFIRVFEKQAQQHGATHLVQGTIYSD
VIESAKSGKKTAAIKSHHNVGGLPERMNLQIVEPLRNLFKDEVRLVGEILGIPRQILYRHPFPGPGLAVRILGEVTEEKL
EILKEADRIFIETLKETGWYEKVWQAFCVLLPVRSVGVRGDKRAYDYVLALRAVDSTEGMTADWSKIPHEVLDLAARRIL
NSVKGIGRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-119 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-119 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-119 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-111 49