Gene Information

Name : Runsl_0776 (Runsl_0776)
Accession : YP_004654348.1
Strain : Runella slithyformis DSM 19594
Genome accession: NC_015703
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 915357 - 916667 bp
Length : 1311 bp
Strand : +
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; COGs: COG0562 UDP-galactopyranose m

DNA sequence :
ATGGTCAGATTAAGAAACAGAATGTATCAGCAACTCCTCCAAAAAGAAAAACAAATCGCGATTATCGGTCTTGGATATGT
AGGATTACCCATTGCCCTCGAATTCGCCAACTATTTTCGAGTGATTGGTTTTGACATTAACCAACAGCGCATTGACATGA
TGAAGGCAGGACAAGACCCTTCTCATGAAATGGACCCGAGTGTTTTTGAAGGAAAAGATATTTATTTTACGGCCAATCCG
GACGATCTGCAACAGGCCCATTTTTTTATCGTGGCCGTTCCTACGCCCGTTGATGATTACAAAGTCCCCGATCTGAAACC
GCTCATCGGCGCGTCGCACGCCATCGGGAAGGCCCTCAAAAAGGGCGATTACGTGATTTATGAGTCGACGGTTTATCCCG
GATGTACCGAAGAAGATTGTCTGCCTATTCTGGAAGCCGAGTCAGGTCTGACCTTAGGCGCGGATTTTAAAATAGGCTAC
TCTCCCGAGCGCATCAACCCCGGGGACAAAGAAAGAACCATTGATAAAATCCTGAAAATAGTTTCCGGAAGCGATGCCGA
AGCGTTGGAGGAAATTGCCTTAGTGTATGGCAAAATCATTACGGCGGGTATCTACAAGGCTCCTACGATTAAAGTGGCCG
AGGCGGCTAAGGTCATCGAAAATACCCAGCGTGACCTCAATATTTCATTGATGAATGAATTGGCCATTATTTTCGACCGT
ATGGGTATTGATACCAAAGATGTGATCGAAGCAGCGGGGACCAAATGGAATTTTATAAAACTATACCCGGGGCTGGTGGG
AGGTCATTGCATTGGCGTTGATCCGTATTATCTGCTGTATAAAGCCAAAAAATTGGGCTATGACCCACAAGTCATTCACA
GCGGACGCCGTATTAATGACGGTATGCCCGCCTTCATTGCCAAACGTCTGGTGCAGATGCTGATCCAAAAAGGGAAGAGT
CCTCAAAATGCAAAAGTGTTGATGATGGGAATCACCTTCAAAGAAAATGTGTCTGATATTCGTAACTCAAAAGTGGCGGA
TCTGGTGAAGGAATTGATGAGTTTTTCGATCAATGTACACCTTGTGGATCCCTATGCCTCCCCCAATGAAGTAGCCCATG
AATACAGTCTGACCCTCATTGACAAACCTTCTACCGAGTACGATGCCGTGATTGTTTCGGTAGGGCACGATCATTACAAA
GCGTTAGACATTGCCTATTTCAAATCCATCATGACCGACAAACCCATTCTGATGGATTTGAAAGGAATGTATAAAAATAC
CGATGAAACCATTACGTATTGGCGTTTATAA

Protein sequence :
MVRLRNRMYQQLLQKEKQIAIIGLGYVGLPIALEFANYFRVIGFDINQQRIDMMKAGQDPSHEMDPSVFEGKDIYFTANP
DDLQQAHFFIVAVPTPVDDYKVPDLKPLIGASHAIGKALKKGDYVIYESTVYPGCTEEDCLPILEAESGLTLGADFKIGY
SPERINPGDKERTIDKILKIVSGSDAEALEEIALVYGKIITAGIYKAPTIKVAEAAKVIENTQRDLNISLMNELAIIFDR
MGIDTKDVIEAAGTKWNFIKLYPGLVGGHCIGVDPYYLLYKAKKLGYDPQVIHSGRRINDGMPAFIAKRLVQMLIQKGKS
PQNAKVLMMGITFKENVSDIRNSKVADLVKELMSFSINVHLVDPYASPNEVAHEYSLTLIDKPSTEYDAVIVSVGHDHYK
ALDIAYFKSIMTDKPILMDLKGMYKNTDETITYWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-97 52
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-97 52
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-91 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Runsl_0776 YP_004654348.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-97 52