Gene Information

Name : Runsl_2666 (Runsl_2666)
Accession : YP_004656198.1
Strain : Runella slithyformis DSM 19594
Genome accession: NC_015703
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : -
Position : 3102311 - 3102805 bp
Length : 495 bp
Strand : -
Note : PFAM: Dihydrofolate reductase; KEGG: bfo:BRAFLDRAFT_89036 hypothetical protein; SPTR: hemagglutinin-related protein

DNA sequence :
ATGCTTCTTTCCCTCATCGTGGCAGCGGCCCAAAATGGCGTCATCGGGCGCGACAATCAACTGATTTGGCACTTGCCCGA
CGACCTGAAACAGTTCAAACGACTCACTACCGGCCATCCGATCCTCATGGGGCGTAAGACATTTGAGTCCATTGGCAAGC
CTCTGCCCAACCGTACGTCTATCGTCATTACACGAAATCAGCATTGGCAGTTTGAGGGCGTTATGGTCGTCAACTCCGTA
GAAGAAGCCATTGAAGCCGCTCGCCAAACCGGAACAGACGAAGCCTTTGTGATCGGCGGAGCGGAAATCTACCGAATGAT
GTTGCCGGCAGTTGATAAGATCTACCTCACCGAAGTAAAAGCAATTTTCGAAGGGGATGCCTTTTTCCGCATTCCCGACC
AAAACAAATGGCGGGAGGTACAGCGGGTGCCTCATGCCGCCGATGAAAAACACGCCGTAGCTTTCGACTTTGTGGAGTGG
GTACGCCGAGATTAA

Protein sequence :
MLLSLIVAAAQNGVIGRDNQLIWHLPDDLKQFKRLTTGHPILMGRKTFESIGKPLPNRTSIVITRNQHWQFEGVMVVNSV
EEAIEAARQTGTDEAFVIGGAEIYRMMLPAVDKIYLTEVKAIFEGDAFFRIPDQNKWREVQRVPHAADEKHAVAFDFVEW
VRRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 6e-27 46
folA-2 YP_189146.1 dihydrofolate reductase Not tested ¥ÕSP¥â Protein 5e-29 44
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 2e-13 42
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 2e-13 42
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 2e-12 41
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 2e-12 41