Gene Information

Name : Runsl_1557 (Runsl_1557)
Accession : YP_004655114.1
Strain : Runella slithyformis DSM 19594
Genome accession: NC_015703
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1770091 - 1772718 bp
Length : 2628 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; InterPro IPR008538; KEGG: sli:Slin_4968 hypotheti

DNA sequence :
ATGAATTTCAACCAATATACCATCAAAGCGCAGGAGGTCATCCAGCGTGCGGTGCAGATCGCTCAGAGCAACCAACAACA
AGCGGTAGAAACGGGACACGTTTTGCAGGCCATTTTGGAAGATGACCCCAACACTTCGCAGTTTTTGATGAAAAAACTGA
ATGTGCAGCCTCAAGTACTGCAAACCAGGATACAGGCCACCGTCAATGCCTATCCAAAAGTAGCAGGTACGGCCGCCACC
GAATACATAAGTAATGATTTAAACAGTGCTTTTCAAAAAGCCCAAACGTACCTGAAGGAATTTCAGGATGAATTTGTCAG
CGTCGAAATGCTGTTTCTTGGCTTGGCCACGGGCAAAGATGCCACCGCCCGACTCATGCAGGAAGCAGGTTTTAAAGAAA
AAGAATTACTGGCCGCCATTAAAGAATTAAGAGGAAAAAATAACCCCGTGAAAGATCAAAATGCCGAAGCAAAGTACCGT
TCACTCGAACGCTACAGCAAAAATTTGAATGAAATGGCCCGGGCGGGAAAAATTGACCCCGTCATCGGTCGCGACGACGA
AATTCGCCGGGTATTGCAGATCTTGGCCCGCCGTACCAAAAACAACCCCATGCTGCTCGGTGAGCCGGGGGTGGGAAAAA
CAGCCATTGTGGAAGGCCTTGCCCAACGTATCGTGCAAGGCGACGTACCCGAACAACTGAAAACTAAAGAGATCGTATCG
CTCGACATGGGCCTGCTCATTGCCGGGGCCAAGTACAAGGGGGAATTTGAAGAACGTCTGAAGGCAGTAATCAAAGAGGT
CACCGATTCTGACGGACAGGTCATTTTGTTCATTGATGAAATCCATACGCTCATCGGGGCGGGGGCCGGTGGTGAGGGCG
CCATGGATGCTGCCAACTTGCTCAAACCGGCCCTCGCGCGGGGCGAACTCCACACCATTGGGGCCACCACCACCAAGGAG
TACCAAAAATACATTGAGAAAGACAAAGCGCTTGAACGCCGCTTTCAGGTCGTCACCGTCGATGAGCCCAACGAACTGGA
TGCCATCAGCATCCTGCGCGGTATCAAAGATAAGTACGAACTTCACCACGGAGTGCGCATTCAGGATGATGCCGTCATTG
CGGCCGTAGAGTTATCAAGCCGGTATATTTCCGACCGTTTTTTGCCCGATAAGGCCATTGACCTGATGGACGAAGCCGCT
GCCAAACTGCGTTTGGAGATGGATTCGGTACCCGAAGAACTCGACGACCTCAACCGCCGCATCATGCAGTTGGAAATCGA
ACGGGAAGCCATTCGTCGCGAAAACGATAAAGACAAAGAAACGCGCCTGAACAAAGAAATTGCCGACCTGAGCGAAGACC
GAAACGCCCTCAAAGCGCAGTGGGAACTGGAAAAAGGCAAAATCAGCGAAGTGCGTACGCTCAAAGAGCAGTTGGACCAG
CTGCGACTGGAAGCCGAGCAGGCCGAGCGCGCCGGCGATTACGGAAAGGTAGCGGAACTTCGTTACGGTAAGATTCCTGA
AATTGAGCAAAAATTGGCCGGTGATATCGGTGAAAATCAATCCAACCAATTGCTCAATGAAGAAGTAACGCCCGAACACA
TCGCGGAAGTAGTGGCCAAATGGACGGGGATTCCGGTCAGTAAGATGCTGCAAAGCGAGCGCGACAAATTACTGAATCTG
GAAACGGAACTTCAAAAACGCGTGGCCGGACAGGAAGAAGCCATCGAAGCCGTAGCCGATGCCGTTCGCCGCTCACGGGC
GGGGCTGCAAGACCCCAAACGCCCCATCGGGAGCTTTTTGTTCCTCGGGCCAACGGGCGTAGGAAAAACCGAACTGGCCA
AAACCCTCGCCAATTACCTGTTCAACGATGAAAACGCCATGGTGCGCATCGACATGAGCGAGTACCAGGAACGCCACTCG
GTCAGCCGTTTGGTGGGAGCGCCTCCCGGCTACGTGGGCTACGACGAAGGCGGTCAGCTGACCGAGGCCGTCAGACGCAA
GCCGTACAGCGTGATCTTGCTGGATGAGATCGAAAAGGCTCACCCGGATGTATGGAACATCATGTTGCAGGTATTGGACG
ACGGCCGCCTGACCGATAACAAAGGACGGATGGCCAACTTCAAGAATACCATCATCATCATGACCTCCAACATCGGCAGC
GATATCATCATGGAGAAGTTCAAAGAAGCGGGCAACAAAACCGACAAAGGTTGGAAGCTGTACTTCAAAGAAGAAGCCAA
AAACGATGTATTGGGCCTGTTGAAACAAACCGTTCGACCTGAGTTCCTAAACCGTATTGACGAGATCGTGCTCTTTGACC
CACTGAGCCACGACAACCTCAAACAAATTGTCCGGATTCAGTTCAACCACATCAAGGGCCTGCTCGCCGAGCAGGGCGTT
ACGCTGGATGCTACCGACGAGGCATTGCTCAAGCTTTCGGAAGAGGGCTACGAACCCGCCTTTGGTGCCCGACCGCTGAA
ACGTGTCCTTCAGCGCCGCATTCTGAACGAGTTGTCAAAACAGATCCTGAGCGGCAAGATCACCAAAGACTCCATTATCA
TGATGGAACTCGGCGAAAACGGCGAAGTCGTTTTTGAGAATATATCGGAAGCGAAACTGGAATTGTAA

Protein sequence :
MNFNQYTIKAQEVIQRAVQIAQSNQQQAVETGHVLQAILEDDPNTSQFLMKKLNVQPQVLQTRIQATVNAYPKVAGTAAT
EYISNDLNSAFQKAQTYLKEFQDEFVSVEMLFLGLATGKDATARLMQEAGFKEKELLAAIKELRGKNNPVKDQNAEAKYR
SLERYSKNLNEMARAGKIDPVIGRDDEIRRVLQILARRTKNNPMLLGEPGVGKTAIVEGLAQRIVQGDVPEQLKTKEIVS
LDMGLLIAGAKYKGEFEERLKAVIKEVTDSDGQVILFIDEIHTLIGAGAGGEGAMDAANLLKPALARGELHTIGATTTKE
YQKYIEKDKALERRFQVVTVDEPNELDAISILRGIKDKYELHHGVRIQDDAVIAAVELSSRYISDRFLPDKAIDLMDEAA
AKLRLEMDSVPEELDDLNRRIMQLEIEREAIRRENDKDKETRLNKEIADLSEDRNALKAQWELEKGKISEVRTLKEQLDQ
LRLEAEQAERAGDYGKVAELRYGKIPEIEQKLAGDIGENQSNQLLNEEVTPEHIAEVVAKWTGIPVSKMLQSERDKLLNL
ETELQKRVAGQEEAIEAVADAVRRSRAGLQDPKRPIGSFLFLGPTGVGKTELAKTLANYLFNDENAMVRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVILLDEIEKAHPDVWNIMLQVLDDGRLTDNKGRMANFKNTIIIMTSNIGS
DIIMEKFKEAGNKTDKGWKLYFKEEAKNDVLGLLKQTVRPEFLNRIDEIVLFDPLSHDNLKQIVRIQFNHIKGLLAEQGV
TLDATDEALLKLSEEGYEPAFGARPLKRVLQRRILNELSKQILSGKITKDSIIMMELGENGEVVFENISEAKLEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 7e-153 47
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-103 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-103 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Runsl_1557 YP_004655114.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-123 45
Runsl_1557 YP_004655114.1 ATP-dependent chaperone ClpB VFG2084 Protein 3e-108 44