Gene Information

Name : guaA (HMPREF0538_20783)
Accession : YP_004649284.1
Strain : Lactobacillus reuteri SD2112
Genome accession: NC_015697
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 774340 - 775956 bp
Length : 1617 bp
Strand : -
Note : COG: COG0519

DNA sequence :
ATGCCATGTTCAGCCTGTAAACTAGCCTTTAAGAATAAAAATTTGAACAAAGGAAGTGTCATTGTGGCAAACATCAATTT
AGATGCGTTTGATAAGATCATTGTCTTGGATTTTGGTAGTCAATACAATCAATTGATTACTCGTCGGCTTCGTGATTTCG
GTATTTATTCCGAATTGCTTTCTCACAAGTTAACCGCAGACGAGATCAAAGAGATTAATCCTAAAGGGATCATCTTCTCT
GGTGGCCCTAATAGTGTTTATGATCCAAACGCATTCAAGGTCGATCCGGAAATCTTTAAGCTTGGTATCCCGATTCTAGG
TATTTGTTATGGAATGCAATTAATGTCATACGACCTTGGCGGAAAGGTTGAAAAAGCTGATAACTCCGAATATGGACGAG
CAGATATTGAAGTACTTGATGACGAGGCTGTATTATTCAAAGGTTTGCCAAAGAAGCAATATGTATGGATGAGTCATGGT
GATTTAGTAACTCAAGCCCCAGCTGGATTTGAAGTTACTGCTACTAGTAAGAACTGTCCAATCGCATCGATTGCTGATAA
TGACCGTAAATTCTATGGTGTTCAATTCCACACTGAAGTTCGTAATTCCGAATACGGATTAGACATTTTACGCCGCTTTG
CTTTTGATGTTTGTGGCGCTAAAGCAAACTGGACGATGGATGACTTCATCGACATGCAGATTAATGAAATCCGCAAAGAA
GTCGGTAATAAGAAGGTTATCTTAGGTCTTTCTGGTGGGGTTGATTCCAGTGTTACCGCCGTTTTGATTCATAAGGCAAT
TGGCGATCAACTTACTTGTATCTTTGTTGACCACGGATTGTTACGGAAGAACGAAGCTGACCAAGTGATGGATGCGTTGA
GTCGCGACCTTGGTGTTAACATTATTAAGGTTGACGCAGCAGATCGCTTCTTAGGTAAGCTTGAAGGTGTTACCGATCCA
GAACAAAAGCGGAAGATTATCGGTAAGGAATTTATCGAAGTCTTTAACGAAGAGGCCAAGAAGATTAAAGATGCTGATTT
CTTAGCTCAAGGTACGCTTTATACGGACGTAATTGAATCTGGAACAGACACCGCCCAGACAATTAAGTCTCACCATAATG
TTGGTGGTTTGCCAAAGAAGCTTGGTTTCAAGTTAATTGAACCATTACGCAAGCTCTTTAAGGATGAAACCCGTGAACTC
GGTGAAAAACTTGGAATTCCACATGAATTGGTATGGCGTCAACCATTCCCAGGTCCAGGTCTTGGAATTCGTGTTATTGG
TGAAATTACTCCTGAAAAGCTTGAAATTGTTCGTGAAAGTGATGCAATCCTTCGTGAAGAAATCAAAAAAGCAGGTCTTG
ATGAAGAAATTTGGCAATACTTTACTGTCTTACCAGGTATTCGTTCAGTTGGTGTCATGGGTGATGGCCGGACATATGAC
TATGCAGTTGCTATCCGGGCCGTTACCTCAATTGATGGGATGACAGCCGATTTCGCTAAGATTCCATGGGATATTCTTCA
AAAGATCTCAGTCCGAATCGTAAATGAAGTCGACCACGTTAACCGCATTCTTTATGATGTTACGAGTAAGCCACCTTCGA
CGATCGAATACGAATAA

Protein sequence :
MPCSACKLAFKNKNLNKGSVIVANINLDAFDKIIVLDFGSQYNQLITRRLRDFGIYSELLSHKLTADEIKEINPKGIIFS
GGPNSVYDPNAFKVDPEIFKLGIPILGICYGMQLMSYDLGGKVEKADNSEYGRADIEVLDDEAVLFKGLPKKQYVWMSHG
DLVTQAPAGFEVTATSKNCPIASIADNDRKFYGVQFHTEVRNSEYGLDILRRFAFDVCGAKANWTMDDFIDMQINEIRKE
VGNKKVILGLSGGVDSSVTAVLIHKAIGDQLTCIFVDHGLLRKNEADQVMDALSRDLGVNIIKVDAADRFLGKLEGVTDP
EQKRKIIGKEFIEVFNEEAKKIKDADFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPKKLGFKLIEPLRKLFKDETREL
GEKLGIPHELVWRQPFPGPGLGIRVIGEITPEKLEIVRESDAILREEIKKAGLDEEIWQYFTVLPGIRSVGVMGDGRTYD
YAVAIRAVTSIDGMTADFAKIPWDILQKISVRIVNEVDHVNRILYDVTSKPPSTIEYE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-173 68
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-173 68
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-173 68
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-129 51