Gene Information

Name : clpC (HMPREF0538_20605)
Accession : YP_004649107.1
Strain : Lactobacillus reuteri SD2112
Genome accession: NC_015697
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 587123 - 589615 bp
Length : 2493 bp
Strand : -
Note : COG: COG0542

DNA sequence :
ATGGATAATATGTTCACGCCAAGTGCAAAGCATGTTCTAGCAATTGCACAAGAACAAGCAAAATACTTTAAACACCAAGC
AGTAGGGACTGAACACCTTCTGCTTGCCCTCTCAATGGATAAAGATGGGATTGCTAACAAAATATTTGAACAATTTTCTA
TTACGAACGATGATATTCGTGAAGAAATTGAACGCTTAATTGGCTATGGAACGATGGAAAATCTGGGAGCTTCAGATTAT
CTCCCATACTCACCAAAAGCAAAGCAAGTATTATCGTTAGCAGGTAAAGAAGCCCAACAAATGCATGCATTGAAGATTGG
CACTGAACACTTATTATTAGCCTTAATCGCTGATGAAAGTGTTCTATCTTCACGGATTTTATATAGTCTAGATGTTGTGC
CACGACAGATGAGAAAAGTAATTTTACGGCGGTTAGGGATTGCTGATAGTCAGCAACGCAATCCTAATCGTCAATCATCT
CGTCGACGGATTCAGCAAACTGGTACACCAACATTAGATAAACTAGCTCGTGATATGACAGAACTTGCTCGGAATGGTCA
GCTTGATCCTGTAATTGGTCGAAATAAGGAAGTTAAACGTGTGGAACAGATTCTTAGTCGTCGTACCAAGAATAACCCAG
TTTTGATTGGAGAACCGGGAGTAGGGAAGACGGCAATTGCTGAAGGACTTGCTCAGCGGATGGTTGATGGTAAGGTTCCA
GCTGAATTGGCTAATAAACGTTTGATGATGCTTGATATGGGATCATTAGTTGCAGGTACCAAGTATCGAGGAGAATTTGA
AGATCGTCTTAAAAAAGTAATTGATGAGATTCAAAACGACGGGCATGTGATTCTTTTTATTGATGAACTCCATACCTTAA
TTGGTGCTGGTGGTGCTGAAGGTGCAATTGATGCCTCCAATATTTTGAAACCGGCCTTAGCGCGAGGCGAGTTGCAAACA
ATTGGTGCTACTACGCTTGATGAATATCAGAAATATATAGAATCGGATGCAGCACTTGAACGACGCTTTGCCACTGTTCA
AGTTGATGAGCCGACTACTGACCAAACTCTACAAATCCTGCGAGGACTACGACCAAAGTATGAGGAGCACCATCATGCTA
AAATTACTGATGAAGCGCTAGAAGAAGCAGTTAAATTGTCAGATCGTTATATTTCGGATCGATTCTTGCCAGATAAAGCA
ATTGATCTTATTGATGAATCGGCAGCTATGGTTCGAATTGATGCTGAAGATAAGAAAAATCATCAGCCTTCACTAGAAAG
TCAGTTAGAAGATTTGCGAACCCAAAAAGAAGAAGCAATTGATAATCAAGACTTTGATCGTGCAGCTACTCTTCGTCAAC
AGGAGTTAGCACTAAAAGATAAGATTGACCGTAAAAAACAACGCACTCAACAAAAAGATTCTCATAACTACAAATTGAAA
GTAACTGGTGAAAACATTGCACAAGTTGTTGCTGAATGGACAGGAGTTCCTTTAACTCAATTGAAGAAGAGTGAAAGTGA
ACGATTGGTTAACTTGGAAAAGGTTCTGCATCAACGAGTAATTGGTCAAGATGAAGCAGTTACCGTAGTCGCTAAGGCAA
TTCGGCGTGCACGAAGCGGTCTTAAGGATCCTAGTCGGCCGATTGGTTCTTTTATGTTTTTAGGACCGACCGGGGTAGGA
AAAACAGAGCTTGCCAAGGCATTAGCTGCTGCAATGTTTGGCTCGGAAGATAATATGATCCGGATTGATATGTCCGAATA
TATGGAAAAATATAGTACTAGTCGCTTGATTGGTGCCGCTCCAGGATATGTCGGTTATGACGAGGGTGGCCAACTAACTG
AAAAAGTACGGCAACATCCATATTCAGTTGTCTTATTAGATGAAGCTGAAAAGGCACATCCGGATGTATTTAATTTATTA
CTTCAAGTTTTAGATGATGGTTACTTAACTGATGCAAAAGGTCGGCGCGTTGATTTTAGAAATACCATTATTATTATGAC
TTCTAACCTTGGAGCAACTCAGCTTCAGGATGAAAAAGAAGTTGGTTTTGGGGCAAAAGATATGTCACAAGACTATAATG
CGATGGCAGCGGCGATTAAGCAACAAATGAGGTTATACTTCCGCCCAGAATTCCTTAATCGGATTGATGAAACGATTATC
TTCCATTCATTACAAAAGAAAGAGCTTCATCAAATTGTTAAACTCATGGTTAATGATTTAAATAAACGGGTAAGTGAGCA
AGGCATTAACTTGAAAGTTACGCCTGCTGCAATTGATGTAATTGCAAAGCTTGGTTACAATCCTGCTTATGGAGCTCGTC
CGCTTCGTCGTGCCTTACAAGATCATGTTGAAGATGATTTGAGTACTGGACTACTTAGTGGTGAAATCAATGTTGGAGAT
GACGTAACAGTAGGTGCGCATCACGGTAAAATTACTTTTAAAGTAAAAAAGCCAGATGAAGATAAAGCTGTTGAATTAAA
ATTGAATAGATAA

Protein sequence :
MDNMFTPSAKHVLAIAQEQAKYFKHQAVGTEHLLLALSMDKDGIANKIFEQFSITNDDIREEIERLIGYGTMENLGASDY
LPYSPKAKQVLSLAGKEAQQMHALKIGTEHLLLALIADESVLSSRILYSLDVVPRQMRKVILRRLGIADSQQRNPNRQSS
RRRIQQTGTPTLDKLARDMTELARNGQLDPVIGRNKEVKRVEQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRMVDGKVP
AELANKRLMMLDMGSLVAGTKYRGEFEDRLKKVIDEIQNDGHVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQT
IGATTLDEYQKYIESDAALERRFATVQVDEPTTDQTLQILRGLRPKYEEHHHAKITDEALEEAVKLSDRYISDRFLPDKA
IDLIDESAAMVRIDAEDKKNHQPSLESQLEDLRTQKEEAIDNQDFDRAATLRQQELALKDKIDRKKQRTQQKDSHNYKLK
VTGENIAQVVAEWTGVPLTQLKKSESERLVNLEKVLHQRVIGQDEAVTVVAKAIRRARSGLKDPSRPIGSFMFLGPTGVG
KTELAKALAAAMFGSEDNMIRIDMSEYMEKYSTSRLIGAAPGYVGYDEGGQLTEKVRQHPYSVVLLDEAEKAHPDVFNLL
LQVLDDGYLTDAKGRRVDFRNTIIIMTSNLGATQLQDEKEVGFGAKDMSQDYNAMAAAIKQQMRLYFRPEFLNRIDETII
FHSLQKKELHQIVKLMVNDLNKRVSEQGINLKVTPAAIDVIAKLGYNPAYGARPLRRALQDHVEDDLSTGLLSGEINVGD
DVTVGAHHGKITFKVKKPDEDKAVELKLNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-94 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004649107.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 0.0 59
clpC YP_004649107.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 2e-157 52