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Name : hsdM (HMPREF0538_20510) Accession : YP_004649012.1 Strain : Lactobacillus reuteri SD2112 Genome accession: NC_015697 Putative virulence/resistance : Unknown Product : type I restriction-modification system DNA-methyltransferase Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : 2.1.1.72 Position : 504726 - 506264 bp Length : 1539 bp Strand : - Note : COG: COG0286 DNA sequence : GTGAAAATGGCAACCAAGTCTAAGGAATTAAGTATTGAGGACAAATTATGGAAAACAGCTGATGCGTTGCGTGGCAGCAT GGACGCTTCAGAATATCGTAATGTTGTACTGGGGTTAATTTTCCTTAAGTATGTATCAGATTCATTTGAAACCAGGCATA ATGAATTGTTGAAATCAGATTATCCTGAAGATGCTGAAGATCCTGATATGTATCTTTCGGAAAATATTTTTTGGGTACCG AAAGAAGCACGTTGGGAATTAATTCAACAATCAGCAAAAACACCTCAAATTGGTGAAATTATTGACAGTGCAATGGATGC AATTGAAAAAAGCAATGATTCATTGCGTGGGGTTTTAAGTAAGAACTATGCATCTCCAGATCTTGATAAAGCTCGTCTAG GTGAAGTGGTTGATTTAATTTCAGATATCAGTCTAGGTGATAAACATGCCAAGCAATCTGATATTTTGGGTCGTGTATAT GAGTACTTTCTCAATGAATTTGCCTCTCAAGAAGGTAAAAAGGGTGGTGAATTTTACACACCACGTTCCATTGTTCGTAC GCTAGTAGAAATGATTGAACCGTACAAAGGACGTATTTATGACCCATGTTGCGGGTCTGGTGGGATGTTTGTGCAATCTG ACAAATTCGTCCAAGAACACCAAGGTAAAATCGGCGACCTATCAGTTTATGGTGAAGAGTCTAACCCAACCACTTGGAAA TTAGCAAAGATGAATCTTGCCATTCGTGGTATTGATAATAACCTTGGGCCACATCAAGGTGATACTTTTACTAATGACCT GCACAAAGGTGAAAGATTTGATTTTATCCTAGCTAATCCACCATTTAATGTAAAAAATTGGAATGGTGACAAGTTGCGTG AAGATGCTCGCTGGCAATATGGAGTTCCACCAGTTGGTAATGCCAACTATGCCTGGATTGAACATATCATTAGCAAATTA GCACCTGATGGGAAAGCCGGATTCGTGTTAGCTAACGGTGCTTTATCAACCTCTACAACGGCAGAGCATGATATTCGTAA AGCAATTCTTGAAGATGACAAGATTGATGCGATCGTCGCCTTACCGGATAAAATGTTTTATTCAACTGGTATCCCAGTTT CACTTTGGTTCGTTGATATGAACAAGGAATCTGAAAATGAACGAGATAGAAAAGGTGAGACTTTATTTATCGATGCGCGT GATCTTGGTGAAATGATTGATCGAACTCATCGGGCATTCTCAAAGGAAGATATTAAAAAAGTAGCAGACACATATCATGC ATACCGTGGTACCAATGATCAAGAGTATAAGGATGTCCCCGGATTTTGTAAGGTAGCCAAACTAGATGAAATTGCAAAGA ATGATTACGTATTAACACCTGGTAGGTACGTTGGCTTAGCAAAACAAGAAGACGATGGTGAACCTTATGAAGTTAAGATG GCTCGTCTGACTGGAGAATTGAAAAAACAGTTTGAGGAGAGTAATAAGCTCCAAGCTGAGATCAAAGATGTATTGAAGGA GCTTGGATATGAAATATAG Protein sequence : MKMATKSKELSIEDKLWKTADALRGSMDASEYRNVVLGLIFLKYVSDSFETRHNELLKSDYPEDAEDPDMYLSENIFWVP KEARWELIQQSAKTPQIGEIIDSAMDAIEKSNDSLRGVLSKNYASPDLDKARLGEVVDLISDISLGDKHAKQSDILGRVY EYFLNEFASQEGKKGGEFYTPRSIVRTLVEMIEPYKGRIYDPCCGSGGMFVQSDKFVQEHQGKIGDLSVYGEESNPTTWK LAKMNLAIRGIDNNLGPHQGDTFTNDLHKGERFDFILANPPFNVKNWNGDKLREDARWQYGVPPVGNANYAWIEHIISKL APDGKAGFVLANGALSTSTTAEHDIRKAILEDDKIDAIVALPDKMFYSTGIPVSLWFVDMNKESENERDRKGETLFIDAR DLGEMIDRTHRAFSKEDIKKVADTYHAYRGTNDQEYKDVPGFCKVAKLDEIAKNDYVLTPGRYVGLAKQEDDGEPYEVKM ARLTGELKKQFEESNKLQAEIKDVLKELGYEI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 1e-168 | 63 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 2e-168 | 63 |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 7e-169 | 63 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 3e-120 | 47 |
