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Name : hsdR (HMPREF0538_20505) Accession : YP_004649007.1 Strain : Lactobacillus reuteri SD2112 Genome accession: NC_015697 Putative virulence/resistance : Unknown Product : type I site-specific deoxyribonuclease Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 498189 - 501305 bp Length : 3117 bp Strand : - Note : COG: COG0610 DNA sequence : GTGTCAAAAGGATACTTATTAGAATCTGATGTCGAAAATCTGGCATTAGATACTCTACAAAAAGTAGGCTATGATGTTTA TAAAAGTCCAAGTACAACTTCTCCTAATCCAGAAATTGACAAGATGCGAAATAATGACCATGCGGTAGCCGTTTTAACTG AAAAACTGCAGGCGTCCCTAAAAAAACTTAACCCAGGCTATCCAGAGGAGATCTATAAAGAGGCCTTACGCCAGTTAACT CGCTTGGCCGATAATCCTGATATGATGGTGAACAATCACTATTTTCATAAATTACTAATTGAGGGAATTCGAGTTAAAAC AACAGTTAATGGTGAAAATCGAACAGAAGTTCTTTATCCAATTGACTTTGACCATGTGGGAAATAACCAATTCGTGGCAA CAAACCAGTTTACTTTTAAGGGTAGTCATGAACGGCGCCCTGATACTACTATCTTTATTAATGGGCTACCAGTGGTGACA TTTGAATTTAAAGATGCTAGCAATCCTAACGTCAGTATTGAGAATGCTTATCGACAATTGCAAACTTATAAAGCTGAGAT TCCTGAATACCTGAAATATAATGAAATTTTGATTGCATCGGATGGTATTAATTCTCGAGCTGGATCTTTAACTGCTGGTT TTGATCGCTTTATGCGCTGGCGAGCACCCAAAAATATTAACGTTGGTGATGACCTTGAATTAGAAACAATGATTAAGTAT ATGCTGACACCTAAGGATTTACTTAATCTAATTGAGAACTTCATTATTTTTGAAACTGATGGTGATAATACAATTAAGAT CCTAGCGGCTTACCACCAGTACTACATGGTTAACAAAGCGGTTAAAGCTGCTAAAAGAACGATGGCTGACCCTAATGACA AACGCATCGGGGTAGTTTGGCATACTACCGGTTCAGGGAAAAGTTTATCGATGGTGTTCTTTGCTAGTATTGTGGCTAGA AAACTTAATAATCCAACAATGCTGGTAATTAATGACCGTAATGATCTAGATGACCAATTGTTTGATACCTTTGCTGCTGC ACATGAATTTTTACGGCAAGCTCCAGAACATGCAGAATCACGTGATGAACTTCGTAAATTTATGGATAAGCAAGCGGGGG AAATTATCTTTTCAACCATTCAAAAGTTCTCACCCGACTTCGAAAGTGGAGAAACTGAAATGCCAGTTTTGACTAATCGG AGTGATGTAATTGTTATTGCGGATGAAGCTCACCGAACTCAATATGGCTTGAAGGCTAAGTTTACTAATAATGGACTACG TTATGGATTTGCTAAGTACTTACGTGACGCTTTGCCTAATGCTTCATTCATTGGTTTTACTGGAACCCCAATTTCTACTG CTGATAAATCAACTGTTGCAGTCTTTGGTAATTACATTGATGTTTATGATATTACTCAGGCCGTTAATGACCACGCCACA GTAAAAATCTATTACGAAAGTCATGTATTCCCTCTGAAGTTGAAGTCCGATGCACAGGCTAAGTATCAACAACTGCTAAA AGAGGCCAACTTAGATGATGATCCTAACTTAGAAGAAAATACTCGACGTAACCGAGAATTCTCCAGTTTGGAGGCATTAG CTGGTGCTCAGCCGCGACTAGAAAGTATTGCTAAGCATTTTGTTAATCATTTCGAAGCACGACAAAAAGAGACTTTTGGC AAGGCAATGATTGTTGAAATGTCGCGTCGTAACGCAGTTCGTCTCTATAATCAAATCATCAAGTTACGCCCAGAGTGGGA TAGTGATGACCTTAATAAAGGGAAAATCAAGGTTGTAATGACGTCTTCTGCGGCCGATGGTCCAGAAATGGCAAAGTTTC AGACCAGTAAAGCTGATCGTCGAGTCCTTCAAAAACGGATGAAAGATAATAATGATGAATTACAGATTGTTATCGTGGTT GATATGTGGTTGACAGGTTTTGACGTACCTTCGATGAATACTATGTACATTGATAAGCCGATGAAGGGACACAATTTAAT TCAAGCTATTGCTCGTGTCAACCGGGTCTTTAAGGACAAAGATAGTGCCTTAATTGTGGACTACATTGGTATCGCTGAAA ATCTGAAAGAAGCGCTGAACGTTTATTCCACAGAAGACCAGGGGCAAGTGGGTATCAATATGCAAAAAGCCCTAGCCCTT TTGAAAGAGAAATATGACATCATTACTAATGATTTCCTATATGGAGTTGATTACTCAGGGTTTGATTCAGAAGATGGAGC TGTTCGCTTAAAGATTACTCGGCGAGTTGCTAACGAGATTCTAGGTGAGGACGAGGAAACACAACAAAAGTTTTTGGATG TTGTGACTGAATTACAGAAAGCTTATGCTTTGACTTCAACTCAACCGGAAGCGCAAGCCTATGGCAAAGAGATTGCTTTC TTTAAGACGGTTAAGGTGTTTATTCAAAAACTAAAGCAACCAACTACGCCTGTCGGTTCAGGAAAACATACTGATGTTAA ATATCAAATGCAACAGTTATTGGATCAGTCCATCATTTCTGAACCCAATGTTGACATCTACAATGAACTAGGCATAAAAA GACAAAGTATTGATTTGATTTCAGATGAATTCTTGCAGAAAGTTAATAGTATGCCGGAGCAGGATGTTGCAATTACCCTG TTGGAAAAATTGCTTAAGGGTAAGATTAAAGCAATGATGAAAAGTAATAAAGTTACGTCCGAAAAATTTGAAGATATGCT CCAGAAATCAATTGACGAATATAATCAACGTGGGATTACTAGTGAAATTGTTATCCGTAAGTTGATTGATATGGCTAAAA AGATTAATGCAGAGCAAGAAAAGGGTAAGGACTTAGGGCTCAGTCAAGAAGAGATCGCCTTTTATGATGCATTAGCTGAT CATAAGAAAGCGGTCGAAGTTCTTGGAGAAAAGAAACTTCATTTGATTGCTCAGGAGCTAGTCAAGCTAGTTAAAGAAGA AGCTGGCGTTGATTGGGAAAAGAGACGTAATATTCAAGCTAAAATGCGTGTAGCTGTAAAACACCTGCTTAGAAAGTATG GTTATCCACCTGATATTGCTCCGGAAGCAGTCAATACCGTGGTAGAACAAGCAGAATTGATGGCAACGAATGATTAA Protein sequence : MSKGYLLESDVENLALDTLQKVGYDVYKSPSTTSPNPEIDKMRNNDHAVAVLTEKLQASLKKLNPGYPEEIYKEALRQLT RLADNPDMMVNNHYFHKLLIEGIRVKTTVNGENRTEVLYPIDFDHVGNNQFVATNQFTFKGSHERRPDTTIFINGLPVVT FEFKDASNPNVSIENAYRQLQTYKAEIPEYLKYNEILIASDGINSRAGSLTAGFDRFMRWRAPKNINVGDDLELETMIKY MLTPKDLLNLIENFIIFETDGDNTIKILAAYHQYYMVNKAVKAAKRTMADPNDKRIGVVWHTTGSGKSLSMVFFASIVAR KLNNPTMLVINDRNDLDDQLFDTFAAAHEFLRQAPEHAESRDELRKFMDKQAGEIIFSTIQKFSPDFESGETEMPVLTNR SDVIVIADEAHRTQYGLKAKFTNNGLRYGFAKYLRDALPNASFIGFTGTPISTADKSTVAVFGNYIDVYDITQAVNDHAT VKIYYESHVFPLKLKSDAQAKYQQLLKEANLDDDPNLEENTRRNREFSSLEALAGAQPRLESIAKHFVNHFEARQKETFG KAMIVEMSRRNAVRLYNQIIKLRPEWDSDDLNKGKIKVVMTSSAADGPEMAKFQTSKADRRVLQKRMKDNNDELQIVIVV DMWLTGFDVPSMNTMYIDKPMKGHNLIQAIARVNRVFKDKDSALIVDYIGIAENLKEALNVYSTEDQGQVGINMQKALAL LKEKYDIITNDFLYGVDYSGFDSEDGAVRLKITRRVANEILGEDEETQQKFLDVVTELQKAYALTSTQPEAQAYGKEIAF FKTVKVFIQKLKQPTTPVGSGKHTDVKYQMQQLLDQSIISEPNVDIYNELGIKRQSIDLISDEFLQKVNSMPEQDVAITL LEKLLKGKIKAMMKSNKVTSEKFEDMLQKSIDEYNQRGITSEIVIRKLIDMAKKINAEQEKGKDLGLSQEEIAFYDALAD HKKAVEVLGEKKLHLIAQELVKLVKEEAGVDWEKRRNIQAKMRVAVKHLLRKYGYPPDIAPEAVNTVVEQAELMATND |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 50 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 50 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 50 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 43 |
