Gene Information

Name : clpE (HMPREF0538_20346)
Accession : YP_004648848.1
Strain : Lactobacillus reuteri SD2112
Genome accession: NC_015697
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 341955 - 344159 bp
Length : 2205 bp
Strand : +
Note : COG: COG0542

DNA sequence :
ATGCAATGTCAATACTGTCATCAAAATCCAGCCACGATTCATCTTCAAATGAATTTTAATGGACAACGGATTCAAATAGA
CCTCTGCCAAAATTGTTATCAAAAATTACAAAATCTACAAACAGATATGATGAATGGAGGTAACGGAATGAATAATTTCG
GTTTTGGAAGCCTCGAAGACTTCATGAACGCAATGAACAATATGCAAAGCCAAGCTGCTGGTGCTAATGGTCAAAACATG
AACGGCCAATCCCAACGACAAGGTGGCGGACGAAATGGAAAAGGAATCCTTGGTCAATATGGGATCAACCTTACTGATCT
CGCTCGCCAAGGTAAAATTGACCCTGTCATCGGGCGCGACAACGAAATTAAACGAGTAATCGAAATTTTAAACCGTCGGA
CCAAGAATAACCCAGTCTTGATTGGTGAAGCTGGGGTTGGTAAGACCGCGGTTGTTGAAGGCTTAGCTCAAGCAATCGTT
AGTGGCCAAGTTCCCGAAAAGCTTGCTAACAAGGAAATTATCCGGCTCGATGTTGTTTCCTTAGTTCAAGGAACAGGAAT
TCGGGGCCAATTTGAAAAACGAATGCAACAATTAATGGAAGAAGTTCGTAAGAATAAAAACATCATCCTCTTTATTGACG
AAATCCACGAAATCATGGGTGCGGGAAATGCTGAAGGCGGAATGGACGCTGGAAATGTTCTTAAGCCTGCCCTTGCCCGT
GGTGACTTCCAATTAGTTGGTGCCACTACTCTTAATGAATATCGAAAGATCGAAAAAGATGCAGCTCTTGCACGACGGTT
CCAACCAGTTGAAGTTGATGAACCATCCGTTGAAGAAACAATCCGCATCTTAAACGGAATCAAAAATCGTTATCAAGATT
ACCACCATGTTAAATACACAGATGACGCAATTGTAGCAGCTGCTAAACTTTCTGACCGCTACATTCAAGATCGTTACTTA
CCTGACAAAGCTATCGACTTACTTGATGAAGCGGGATCAAAGAAGAACTTAACGCTTAAAAATGTGGATCCAAACGCAAT
CGAAAATGAAATCCACACAGCTGAAGCACACAAGCAACAAGCAGCTGATAACCAAGACTATGAAAAAGCAGCTTTCTACC
GCGATCAAGTCGCTAAACTTGAAAAGGCAAAGAAAGAAGCTGAAGAAAACCATACTGAAGATTCTGCAACTGTTACCGTT
AAGGATATGCAGAGAATCGTTGAAGAACGGACAAATATTCCAGTTGGTGACCTGCAAAAGCAAGAAGAAAATCAACTTCG
CGACCTTGATAAGAAGCTTGATGAACATGTTATTGGTCAAACCCAAGCAGTGGATAAGGTTGCCCGTGCCATTCGTCGTA
ACCGGATCGGTTTGAACAAGTCTGGTCGGCCAATTGGTAGTTTCCTCTTTGTTGGTCCTACGGGGGTTGGTAAGACTGAA
ACGGCTAAGCAACTTGCCCTCCAATTGTTTGGTTCTAAGGATGCCATGATTCGGTTTGATATGTCTGAATACATGGACAA
GACCTCTACTTCTAAATTAATCGGGGCTGCTCCTGGTTATGTTGGTTACGAAGAAGCTGGTCAGTTGACTGAACAAGTAC
GGCGGCACCCTTACAGCTTGATCTTACTTGATGAAGTTGAAAAGGCGCACCCAGATGTTATGCACATGTTCTTACAAATT
CTTGATGATGGTCGTTTAACTGATTCTCAAGGACGCACTGTTAGCTTCAAGGATACAATCATTATCATGACATCTAATGC
CGGAACTGGTGATTCAGAAGCAAGTGTTGGTTTCGGTGCTGAGTCTAATGGTAGTACCCACTCCATCATTGACAAGTTGA
CAAACTACTTCAAGCCAGAATTCTTAAACCGGTTTGATGACATTGTTCAATTCAATGCCCTCTCTAAAGATGACTTGATG
AAGATCGTTAACTTAATGATTGATGATGTTAATAACATGCTTGCTGATAAGAACTTGCACATCGAAGTCACTAACAATGT
TGAAGAAAAATTAGTTGACATGGGCTTTGATCCAAAGATGGGTGCTCGTCCTCTTCGCCGGGTAATCCAAGAACAAATCG
AAGACCGGATTGCTGATTACGTTCTTGATCACAGTGACGCTCATAAATTAGTTGCTAAACTTGATGATAATGGTGACATT
GTTGTCGAAGAAACTGACGAAGTACCAACAATTGCTAAAAAATAA

Protein sequence :
MQCQYCHQNPATIHLQMNFNGQRIQIDLCQNCYQKLQNLQTDMMNGGNGMNNFGFGSLEDFMNAMNNMQSQAAGANGQNM
NGQSQRQGGGRNGKGILGQYGINLTDLARQGKIDPVIGRDNEIKRVIEILNRRTKNNPVLIGEAGVGKTAVVEGLAQAIV
SGQVPEKLANKEIIRLDVVSLVQGTGIRGQFEKRMQQLMEEVRKNKNIILFIDEIHEIMGAGNAEGGMDAGNVLKPALAR
GDFQLVGATTLNEYRKIEKDAALARRFQPVEVDEPSVEETIRILNGIKNRYQDYHHVKYTDDAIVAAAKLSDRYIQDRYL
PDKAIDLLDEAGSKKNLTLKNVDPNAIENEIHTAEAHKQQAADNQDYEKAAFYRDQVAKLEKAKKEAEENHTEDSATVTV
KDMQRIVEERTNIPVGDLQKQEENQLRDLDKKLDEHVIGQTQAVDKVARAIRRNRIGLNKSGRPIGSFLFVGPTGVGKTE
TAKQLALQLFGSKDAMIRFDMSEYMDKTSTSKLIGAAPGYVGYEEAGQLTEQVRRHPYSLILLDEVEKAHPDVMHMFLQI
LDDGRLTDSQGRTVSFKDTIIIMTSNAGTGDSEASVGFGAESNGSTHSIIDKLTNYFKPEFLNRFDDIVQFNALSKDDLM
KIVNLMIDDVNNMLADKNLHIEVTNNVEEKLVDMGFDPKMGARPLRRVIQEQIEDRIADYVLDHSDAHKLVAKLDDNGDI
VVEETDEVPTIAKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 8e-151 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_004648848.1 ATP-dependent Clp protease VFG0080 Protein 0.0 58
clpE YP_004648848.1 ATP-dependent Clp protease VFG0079 Protein 2e-157 53