Gene Information

Name : HMPREF0538_20241 (HMPREF0538_20241)
Accession : YP_004648744.1
Strain : Lactobacillus reuteri SD2112
Genome accession: NC_015697
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 232986 - 233672 bp
Length : 687 bp
Strand : -
Note : COG: COG0745

DNA sequence :
ATGAGTCGAATTTTAATTATTGAGGATGAGGAAAATTTAGCAAACTTTGTAGAACTTGAATTAAAGCATGAAGGCTACGA
TACAGATGTTGAACTTGATGGTCGTGCCGGACTAGAAGCAGCTTTAAATCAAGACTTTGACGTAATTTTGCTAGACCTGA
TGCTCCCAGAGTTAAATGGGATTGAAGTGGCACGGCGGGTTCGTGAATTAAAAGATACGCCAATTATTATCATGACTGCT
CGTGATTCTGTTATTGACCGTGTCTCTGGATTAGATCACGGGGCAGATGATTATATTGTTAAGCCGTTTGCGATTGAAGA
ACTCCTTGCACGGGTCCGGGCGTTATTGCGGCGAATCAGTATTGAAGATGGTAATAATAAGGAACATCAAACAACGGTCA
ATTACAAGGATCTTACCATTGAAAAAGAGAACCGGGTTGTTCGTCGCGGCGATGAAGTAATTAACCTTACCAAGCGGGAA
TACGAATTACTGTTGATCTTAATGGAAAATATCAATGTTGTTATGTCACGAAAAGACCTTTTGAGTAAGGTATGGGGTTA
TGATTCCAAGGTTGAAACCAATGTTGTTGATGTTTATATTCGGTACTTGCGGAATAAGATCGACCGTCCTGGTGAAAAGA
GCTACATCCAAACGGTTCGTGGTACTGGATATGTGATTCGCTCCTAG

Protein sequence :
MSRILIIEDEENLANFVELELKHEGYDTDVELDGRAGLEAALNQDFDVILLDLMLPELNGIEVARRVRELKDTPIIIMTA
RDSVIDRVSGLDHGADDYIVKPFAIEELLARVRALLRRISIEDGNNKEHQTTVNYKDLTIEKENRVVRRGDEVINLTKRE
YELLLILMENINVVMSRKDLLSKVWGYDSKVETNVVDVYIRYLRNKIDRPGEKSYIQTVRGTGYVIRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 5e-27 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 1e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator HE999704.1.gene1528. Protein 5e-75 71
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_002951.3238224.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_007793.3914065.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_002758.1121390.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_010079.5776364.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_002952.2859858.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_007622.3794948.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_003923.1003417.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator NC_013450.8614146.p0 Protein 1e-49 54
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator AE015929.1.gene1106. Protein 8e-45 52
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator BAC0125 Protein 4e-34 43
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator BAC0197 Protein 1e-30 42
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator BAC0308 Protein 6e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator VFG1390 Protein 2e-37 44
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator VFG1563 Protein 3e-27 41
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator VFG1702 Protein 4e-27 41
HMPREF0538_20241 YP_004648744.1 DNA-binding response regulator VFG1389 Protein 2e-34 41