Gene Information

Name : F7308_0763 (F7308_0763)
Accession : YP_004647290.1
Strain : Francisella sp. TX077308
Genome accession: NC_015696
Putative virulence/resistance : Virulence
Product : UDP-glucose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.22
Position : 777618 - 778892 bp
Length : 1275 bp
Strand : +
Note : -

DNA sequence :
ATGAGTAAAAAAATATGTGTAGTTGGTTTGGGTTATGTTGGGCTTCCATTAGCTCATGCATTTGCTAAAAAGTTTGATGT
GGTTGGTTTTGATATTAGTAAATCTAGGATTGCAGAACTTGAGAGATGCTATGACAGAACATTGGAATTAACTACAGAAC
AGTTAGAAGATATCAAGGATGTTATTACTTACACTTGTGACATAGATGTTGCAAAAGACTGTAATGTTTATATAGTTACA
GTCCCGACACCTATTGACTCTATGAATAATCCAGATTTAACTCCGCTTAGAGACGCATCTTTGATAGTAGGTTCTGTTTT
AAAAGAAAATGATATCGTGATATACGAATCTACAGTATATCCGGGGGTTACTGAAGAGGTTTGTGTGCCATATTTAGAAG
ACAGATCTGGTCTGGTTTTTAACAAAGATTTCTTCTGTGGTTATTCTCCAGAGAGAATTAACCCAGGTGATAAAGAGCAT
ACTGTTACAAATATCCTAAAGATAACTTCAGGTTCTACTCCTGAGGTTGCGACAATAGTTGATGATTTATACAACGCTAT
AATTGTAGCTGGTACTCACAAGGCAAGTTCAATAAGGGTTGCTGAAGCCGCTAAAGTTATTGAAAATACTCAAAGGGATG
TAAATATTGCTTTAATCAATGAGTTAGCAATGATCTTTGATAGTATGGGTATTCCAACTCATGATGTGATTGAAGCAGCA
GGTACTAAGTGGAACTTTATTAAGCTAAAGCCTGGTCTGGTTGGTGGGCATTGTATCGGAGTAGATCCATATTATCTAAC
ATACAAAGCAGAAGAGCTAGGGTACAAACCAAACTTGATTTTGGGTGCTAGACAGATTAATAATGGTATGGGCAAATATA
TTGCTGAGAAGACAGTTAAATTGATGATCAAAGAGCGTAAGCATGTATGTGAATCTAATGTTTTAGTACTTGGATTTGCA
TTTAAAGAAGACTGTCCTGACACTAGAAATACAAAAGTAGTTGATATAATAACTAATCTTAAAGAATTCGGCGTAAATGT
GTCTGTGTTTGATCCACAGATGGATGAGGCAGATGAGAAACATTATCCAAATATTAAATTTATCAAGAACCCATTTGGTG
GTAAAACTACCTATGATTCGGTAGTAGTTGCTGTAGGACATAGAGAGTTCAAAATGTATTCTACAATGGATTATAAAGCA
TTATTTGCAAAAGATGATAAGCCAGTATTAGTTGATGTCAAAGGTATACTAAAAGATTATAACTGGAGATTATAA

Protein sequence :
MSKKICVVGLGYVGLPLAHAFAKKFDVVGFDISKSRIAELERCYDRTLELTTEQLEDIKDVITYTCDIDVAKDCNVYIVT
VPTPIDSMNNPDLTPLRDASLIVGSVLKENDIVIYESTVYPGVTEEVCVPYLEDRSGLVFNKDFFCGYSPERINPGDKEH
TVTNILKITSGSTPEVATIVDDLYNAIIVAGTHKASSIRVAEAAKVIENTQRDVNIALINELAMIFDSMGIPTHDVIEAA
GTKWNFIKLKPGLVGGHCIGVDPYYLTYKAEELGYKPNLILGARQINNGMGKYIAEKTVKLMIKERKHVCESNVLVLGFA
FKEDCPDTRNTKVVDIITNLKEFGVNVSVFDPQMDEADEKHYPNIKFIKNPFGGKTTYDSVVVAVGHREFKMYSTMDYKA
LFAKDDKPVLVDVKGILKDYNWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-101 55
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-101 55
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-100 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
F7308_0763 YP_004647290.1 UDP-glucose dehydrogenase VFG0431 Protein 1e-101 55