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Name : F7308_0305 (F7308_0305) Accession : YP_004646833.1 Strain : Francisella sp. TX077308 Genome accession: NC_015696 Putative virulence/resistance : Unknown Product : type I restriction-modification system, R subunit Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : 3.1.21.3 Position : 297840 - 300989 bp Length : 3150 bp Strand : + Note : - DNA sequence : ATGAAAGAAGACAATATAGAAAACTACGCAATCGATCTATTTAAGTCAGAGGGCTATAACTATATATATGCTCCTGATGT AGCACCAGATACTGATAATCCTATTAGAGCTACATTTTCAGATGTGGTATTAGAAAATCTTCTGCGAGATAAGCTTCTAG AAATTAACCCACAAATTCAGCCAAATTTAATAGATGATGCTATCAAAAAACTTTTGCGTACTTCTTCTGATGAGCTTTTA GCTGATAATGAGCTTATTCATCAATATATTACTCAAGGTATCAAGGTTGAATATACTAAAGATGGTGCGACTAGAGGCGA GATTGTCAAACTTATAGATTTTGATAACTCTAGTAATAATGATTTCACGGTAATGAATCAGTTTACTATTATTGAGAATG ATAATAATAAACGCCCAGATTTAATTATTTTCGTCAATGGTTTGCCATTGGTAGTTATAGAGCTAAAAAATGCTACTGAT GAAAATGCAACTATCAAATCAGCATTTGACCAAATTCGTACTTATAAGGCAACTATTCCAAGCTTATTTAGATATAACGC TATTTGTGTGATTAGTGATGGGTTAGAAGCAAAGGCTGGGACTATTTCAGCTGATATTAGCCGTTTTATGACTTGGAAGT CTAGTGATGGTATAGCTGAGAGTTCAAAACTAGTACCACAATTAGAAACTCTAATTTTAGGGATGCTAAATCCTATAACC TTATTAGATCTTATCAAAAACTTTATCGTATTTGAGAAAGATAAAAAGCAAGATGAGAAAGGACAAACTCAAGTTTTCAC AATCAAGAAGTTAGCAGCATATCATCAATATTATGCAGTTAATAAAGCTCTTGAGAGAACACTACAAGCTAGCCACAAAG ATGGTGATAAAAAAGGTGGTGTAGTATGGCATACTCAAGGTAGTGGTAAATCGCTATCGATGGTTTTTTATACAGGTAAA GCTGTACTAGCACTAAATAACCCAACTATAGTAGTTATTACAGATAGAAACGACCTTGATGATCAGTTATTTGATACTTT TGCAGCATCAAAAAGCCTTCTAAGACAAACTCCAGTGCAAGCTAACACTAGAGAAGATCTCAAAAGGCTACTTAAAGTAG AAAGTGGTGGTATTGTATTTACAACTATCCAAAAATTCCAACCAGAAGAGGGTAATGTTTACGATACATTATCAGCAAGA GATAATATTATCGTAGTAGCAGATGAGGCACACCGTACCCAATATGGCTTTAGTGCAAAGACTGTAGATGATAAGGATGA ACAAGGTAATATCATCGGTAAAAAGACAGTTTATGGCTTTGCTAAATATCTGCGTGATGCTCTACCTAATGCTACATATC TAGGCTTTACAGGTACCCCAGTTGAGGCGAATGATAAAAACACCCCTATGGTTTTTGGTGATTATGTTGATATTTATGAT ATATCACAAGCTATAGATGATGGTGCAACTGTGCCGATATATTATGAATCTCGTTTGGCTAAGATAAATCTAAGTGAAGA GGGCAAAGAGCTTGTCAAAGAACTAGATGACGAGATCGGTGAGTTAGATGAATCACAAAAGACAAAAGCAAAATGGACAA GGCTAGAGGCTCTAATTGGTGCTGAGAATCGTATCAAAGAAGTAGCTAATGATATTGTTAATCATTTTGAAGCTCGCCAA GAAGTCTGTGATGGCAAGGCTATGATTGTTGCTATGAGTCGTAGAATAGCTGTTAGATTATATGATGAGATTATCAAACT TCGCCCAGCATGGCATGATAAAGATTTGGATAAAGGTGTTATAAAAGTTGTAATGACAGCTAGCTCTAGTGATGGGCCAG AAATGGAGCAACACCACACAAGCAAGCAACAACGCCGTAATCTTGCAAACCGTATGAAAGATACTAAAGATGAGCTAAAA CTAGTAATAGTCCGTGATATGTGGCTAACAGGTTTTGATGCACCATCTATGCATACTCTATATATCGATAAACCTATGCA AGGTCATAATCTAATGCAGGCTATAGCAAGAGTTAATAGAGTCTACAAAGACAAGCCAGCAGGATTGGTAGTTGACTATC TAGGTATAGCAAGTGATCTTAAAAAAGCTCTATCTTTCTATAGTGATAGTGGTGGTAAAGGTGATCCAGCACAGACACAA GAAAAAGCAGTTAGCCTAATGCTTGAGAAATTAGAAGTAGTCTCACAAATGTTTCATGGTTTTGACTATGAGAAATACTT TGATGCTGATACAAGGCAGAAATTAGCTATTATCTTAGAAGCAGAGGATTTTATTTTAGGCTTAGAAAATGGTAAAAAAC GCTTTGTAAATGAAGTGACAGCTTTATCAAAAGCTTTTGCAATAGCTATGCCACATGATGAGGCAGTAGATGCCAAAGAT GAGATAGCATTTTTCCAAGCTATTAAAGCAAGATTGGCAAAATTTGACTCTACAGGAACAGGCAAAACTGATGAGCAGAT AGAGACAGCTATTCGCCAAGTTATTGATAAGGCTCTAGTAACAGATCAAGTTATAGATATATTTGATGCAAGCGGTATCA AAAAACCAGATATATCAGTATTATCAGATGAGTTTCTAGCTGAAGTTAGAGATTATAAGCATAAGAACATTGCTTTAGAA ACACTCAAAAAGCTTCTAAACCAAGAGATAAAAGCTCGCTCTAAAACTAATCTAGTCCAAGCAAAGACTCTTAAAGAGAT GCTCGAGGATTCGATTCGCCGTTATCATAGCAAGGCTATTTCATCAGTTGAGTTTTTAGATGAGCTAATAAACCAAGCTA AAGAAATTAAAAACATGGATACAGAGTATCAAAAGCTAGGTTTGACAGAGTATGAGTATGCTTTCTATACAGCAGTAGCA AATAATGAGAGTGCTAAAGAGATTATGCAGACTGACAAGTTGCGAGAACTAGCGATAGAGTTATTTAATCGCTTAAAATC ATCAGCTTCTATTGATTGGACTAAAAAAGAATCTGTGAGGGCTAAGCTTAGAGTTACAGTCAAAAGAACTCTCAGACAAT TTGGCTATCCACCAGATATGCAAAAGATTGCGACAGATACTGTACTTAAACAAGCAGAGCAAAGCACCCTGTCGCAAGCT AAGGGCACAGTAACAAGTTTGCTAGCCTAA Protein sequence : MKEDNIENYAIDLFKSEGYNYIYAPDVAPDTDNPIRATFSDVVLENLLRDKLLEINPQIQPNLIDDAIKKLLRTSSDELL ADNELIHQYITQGIKVEYTKDGATRGEIVKLIDFDNSSNNDFTVMNQFTIIENDNNKRPDLIIFVNGLPLVVIELKNATD ENATIKSAFDQIRTYKATIPSLFRYNAICVISDGLEAKAGTISADISRFMTWKSSDGIAESSKLVPQLETLILGMLNPIT LLDLIKNFIVFEKDKKQDEKGQTQVFTIKKLAAYHQYYAVNKALERTLQASHKDGDKKGGVVWHTQGSGKSLSMVFYTGK AVLALNNPTIVVITDRNDLDDQLFDTFAASKSLLRQTPVQANTREDLKRLLKVESGGIVFTTIQKFQPEEGNVYDTLSAR DNIIVVADEAHRTQYGFSAKTVDDKDEQGNIIGKKTVYGFAKYLRDALPNATYLGFTGTPVEANDKNTPMVFGDYVDIYD ISQAIDDGATVPIYYESRLAKINLSEEGKELVKELDDEIGELDESQKTKAKWTRLEALIGAENRIKEVANDIVNHFEARQ EVCDGKAMIVAMSRRIAVRLYDEIIKLRPAWHDKDLDKGVIKVVMTASSSDGPEMEQHHTSKQQRRNLANRMKDTKDELK LVIVRDMWLTGFDAPSMHTLYIDKPMQGHNLMQAIARVNRVYKDKPAGLVVDYLGIASDLKKALSFYSDSGGKGDPAQTQ EKAVSLMLEKLEVVSQMFHGFDYEKYFDADTRQKLAIILEAEDFILGLENGKKRFVNEVTALSKAFAIAMPHDEAVDAKD EIAFFQAIKARLAKFDSTGTGKTDEQIETAIRQVIDKALVTDQVIDIFDASGIKKPDISVLSDEFLAEVRDYKHKNIALE TLKKLLNQEIKARSKTNLVQAKTLKEMLEDSIRRYHSKAISSVEFLDELINQAKEIKNMDTEYQKLGLTEYEYAFYTAVA NNESAKEIMQTDKLRELAIELFNRLKSSASIDWTKKESVRAKLRVTVKRTLRQFGYPPDMQKIATDTVLKQAEQSTLSQA KGTVTSLLA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 51 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 50 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 50 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 47 |
