Gene Information

Name : aadK (KNP414_04261)
Accession : YP_004642663.1
Strain : Paenibacillus mucilaginosus KNP414
Genome accession: NC_015690
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4441435 - 4442322 bp
Length : 888 bp
Strand : -
Note : Aminoglycoside 6-adenylyltransferase

DNA sequence :
ATGAAACCGGTTGGAACGGAGGAATACTGCTTGAGAAGTGAACATGAAATGATGAGTACCATTATCAATTTCGCTAAAAA
TGATGATAGAATACGACTGGCAACTTTGGAAGGGTCACGTACAAACAAAAATATTCCCGTTGATACATTCCGGGATTATG
ACATCTCTTACTTTGTAACAGATATTGAATCTTTCAAAGAGACTGACCAATGGCTTGAATTTTTTGGGAATCGGCTTATG
ATGCAAAAACCCGAAGATATGGAGCTTTTTCCGTCAGAGCTAGGTAACTGGTTTTCATATATAATTCTTTTTGAGGATGG
TAATAAGTTAGACTTAACACTTATTCCAATTAACGAAGTGGGGGATTATTTTACCAAGAACGACGGTTTAGTTGAGGTCC
TGCTTGATAAGGATACTCTAATCAATAATGAAGTGATCGCAGACGATCGTCAATATTGGATTAAAAAGCCGACCGCAAGA
GCATTTGATGATTGTTGTAATGAGTTCTGGATGGTTTCAACGTACGTAGTAAAAGGACTAGCCAGAAAAGAAATACTCTT
TGCGATTGACCATTTAAACGAGATTGGAAGACCTAATCTATTAAGAATGATGGCTTGGCAAATCGGGTCTGAACACGGAT
ATACTTTTAGCGTAGGGAAGAACTATAAATTTATTAATCGTTACCTTCCTAATGAAGATTGGGAAAAGCTCCTATCAACC
TATTCTGAGAATGGGTATCAGGAAATGTGGCAGTCGTTATTAACTTGTTATGAGTTATTTAGAAAATACTCAAAAGCTGT
GTCAGAAAGTCTCGGCTATACGTATCCAGATTATGACGAAGCTATTACTAAGTATACGGAAAATATTTACTCCTCATTAG
TAATTTAG

Protein sequence :
MKPVGTEEYCLRSEHEMMSTIINFAKNDDRIRLATLEGSRTNKNIPVDTFRDYDISYFVTDIESFKETDQWLEFFGNRLM
MQKPEDMELFPSELGNWFSYIILFEDGNKLDLTLIPINEVGDYFTKNDGLVEVLLDKDTLINNEVIADDRQYWIKKPTAR
AFDDCCNEFWMVSTYVVKGLARKEILFAIDHLNEIGRPNLLRMMAWQIGSEHGYTFSVGKNYKFINRYLPNEDWEKLLST
YSENGYQEMWQSLLTCYELFRKYSKAVSESLGYTYPDYDEAITKYTENIYSSLVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 9e-83 58
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 5e-76 57
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 9e-81 56
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 9e-81 56
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 8e-59 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadK YP_004642663.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 8e-78 59
aadK YP_004642663.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 1e-75 58
aadK YP_004642663.1 aminoglycoside 6-adenylyltransferase AJ489618.1.orf2.gene Protein 4e-61 57