Gene Information

Name : mccB (SMB_G0947)
Accession : YP_004635594.1
Strain : Clostridium acetobutylicum DSM 1731
Genome accession: NC_015687
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1071342 - 1072487 bp
Length : 1146 bp
Strand : +
Note : -

DNA sequence :
ATGAAAATAGAATCATTGGTAATTCATGGAGGAAAAGATGGAGACGAATATACAGGTGCAGTAAATGTCCCTATATATCA
AACTTCAACCTTTAAACAAGAAAAGTTAGGTGTAAACAAAGGATATGAATATTCAAGAACAGGAAATCCAACAAGAGAAG
CTGTTGAAAAGCTTATTTCAGATTTAGAGGAAGGTCAATCTGGTTTTGCATTTGCTTCTGGAATGGCAGCTATTACAGCA
GTTTTATCTTTATTTAAAACAGGAGATAAAATAATTATATCAAACAATGTTTATGGTGGAACTTTTAGAGTTTTAGATAA
GGTATTTAATCATTTTAATATAGGTTATAAAATAGTTGATACTTCAAAGGTTCAAGAGATAAGGGATAATATAGATAAGG
ATGTAAAGGCTATATACATTGAAAGTCCTACTAATCCACTTATGGATATTACGGATATTAAGCTTGTTTCAAGTATAGCA
AAAGAAAACAATCTTCTTACTATAGTTGATAATACCTTTATGACACCATATCTTCAAAAACCACTAACACTTGGTGCAGA
TATAGTACTTCATAGCGCTACAAAGTATTTAGGTGGACACAGTGATTTGGTGGCGGGTCTTGTAGTGGTTAACAATAAAG
ATTTAGCTGAAAAGCTTCATTTTATACAGAATTCAACTGGAGGAGTACTTGGACCTTTTGATTCATTTCTTCTTATAAGG
GGTATAAAAACTCTTGCAGTAAGAATGGATAGGCATACTGATAATGCAAAGAAGATAGCTTCTCTGTTAAATCATAGAAA
AGAAATAGAAAAAGTATACTATCCTGGACTTGAGGAGCATATAGGGCATGAGGTCCAAAAAAAGCAGGCTTCTGGTTATG
GCGCAATAATATCATTTGTTATAAATGAAAAATACGACTATAAAAAGTTTATTGAGAATTTAAAACTTATTACCTTTGGA
GAAAGTTTAGGTGGAGTTGAATCACTTATATGCCATCCAGCTAGTATGACACATGCAGCAATTCCATATGAAATAAGACA
GAAAGTTGGTATTGTAGATAACTTAATAAGACTTTCTGTAGGAATTGAAAATGGTGATGATTTAATAGAAGACTTGTTGA
AAGCTCTTGAGGGGAGTGAAAAATAG

Protein sequence :
MKIESLVIHGGKDGDEYTGAVNVPIYQTSTFKQEKLGVNKGYEYSRTGNPTREAVEKLISDLEEGQSGFAFASGMAAITA
VLSLFKTGDKIIISNNVYGGTFRVLDKVFNHFNIGYKIVDTSKVQEIRDNIDKDVKAIYIESPTNPLMDITDIKLVSSIA
KENNLLTIVDNTFMTPYLQKPLTLGADIVLHSATKYLGGHSDLVAGLVVVNNKDLAEKLHFIQNSTGGVLGPFDSFLLIR
GIKTLAVRMDRHTDNAKKIASLLNHRKEIEKVYYPGLEEHIGHEVQKKQASGYGAIISFVINEKYDYKKFIENLKLITFG
ESLGGVESLICHPASMTHAAIPYEIRQKVGIVDNLIRLSVGIENGDDLIEDLLKALEGSEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-98 53
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-99 53
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-68 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mccB YP_004635594.1 cystathionine gamma-synthase BAC0207 Protein 9e-65 41