Gene Information

Name : pykA (SMB_G0528)
Accession : YP_004635179.1
Strain : Clostridium acetobutylicum DSM 1731
Genome accession: NC_015687
Putative virulence/resistance : Virulence
Product : pyruvate kinase (pykA)
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 597261 - 598682 bp
Length : 1422 bp
Strand : +
Note : -

DNA sequence :
ATGCAAAAAACTAAAATGATTTTTACAGTTGGACCAGCAAGTGAGACAGAGGAGATTGTAACAGCTTTCATAAAAGCTGG
AATGAATGCTTCAAGACATAACTTTTCACACGGTGATCATGCAGAGCACGGTGGAAGAATAGCTTTAGTAAAAAAGGTTA
GAGCAAAGCTTAATAAGCCTGTAGCTATATGCCTTGATACTAAAGGACCAGAAATAAGAACTGGAGATTTCAATCCTTCA
AAGCTTGAACTTCAAAAAGGTTCAAAATTTACTATCGTTTGTGGCGAAGAAATAGTTGGAGATGCTACAAAATGTTCAAT
ATCATATAAAGATTTATACAAAGATGTAAAACCAGGAAACACTATATTAATAGATGATGGTTTAGTTGGACTTACAGTAG
AAGCTATAGAAGGAACAAATGTAATTTGTACTGTAGCAAATACAGGATTAGTTGGAAGCCATAAAGGAGTAAATGTTCCA
AACGTTTCAATACAACTTCCTGCAATGACAGAAAAAGATAAGAGCGATTTAATATTCGGATGTAAAGAAGAAATAGATAT
GGTAAGTGCATCATTCATAAGAAAACCTGAAGATGTACTTGCAATAAGAAAAGTATTAAATGAGAATGGCGGAGAAAACA
TTCAAATATTCTCTAAAATTGAAAATCAAGAAGGCGTGGACAACATAGATGCTATTATAGAAGTTTCTGACGGAATAATG
GTAGCTAGAGGAGATATGGGAGTTGAAATTCCTATACAAAGAGTTCCATTAATCCAAAAAATGATAATCAAAAAATGTAA
TGCAGTAGGAAAACCTGTTATAACAGCAACTCAAATGCTTGATTCAATGATGAGAAATCCAAGACCTACAAGAGCAGAAG
CTTCAGATATAGCAAATGCTATATTTGATGGAACAGATGCTATAATGTTAAGTGGAGAAAGCGCTAATGGATCATATCCA
ATAGAAGCTGTAACTACAATGGCAAAAATAGCACAAGAGGCAGAAAATGAAATCAATTATGATAAATTCCTAGCAGAAAG
AAAAGGAAATGAAAAGAAAAATACTTCTGATGTAATAAGTCTTGGAACTTGCACAGCAGCAGCAGACTTAGAAGCTTCAG
CAATAATAACTGCAACTCAAACAGGAAGCACAGCAAGAACAGTTTCAAAATATAGACCAAAAGCACCTGTAATAGCAGTT
ACTCCATCTGAAAAAGTAGCAAGAAAACTTGCAATGAGCTGGGGAGTACACCCTATAATATCTGATAAATTTGGTTCAAC
TGATGAACTTATCTCTACTTCAGTAGATAAAGCCCTTGAAGCAGGATATGTACAAAAAGGAGATCTTGTAGTTGTAGCTG
CAGGTGTACCAACAAATGTATCAGGTACTACAAACATGCTTAAAGTTCAAGTTGTTGAGTAA

Protein sequence :
MQKTKMIFTVGPASETEEIVTAFIKAGMNASRHNFSHGDHAEHGGRIALVKKVRAKLNKPVAICLDTKGPEIRTGDFNPS
KLELQKGSKFTIVCGEEIVGDATKCSISYKDLYKDVKPGNTILIDDGLVGLTVEAIEGTNVICTVANTGLVGSHKGVNVP
NVSIQLPAMTEKDKSDLIFGCKEEIDMVSASFIRKPEDVLAIRKVLNENGGENIQIFSKIENQEGVDNIDAIIEVSDGIM
VARGDMGVEIPIQRVPLIQKMIIKKCNAVGKPVITATQMLDSMMRNPRPTRAEASDIANAIFDGTDAIMLSGESANGSYP
IEAVTTMAKIAQEAENEINYDKFLAERKGNEKKNTSDVISLGTCTAAADLEASAIITATQTGSTARTVSKYRPKAPVIAV
TPSEKVARKLAMSWGVHPIISDKFGSTDELISTSVDKALEAGYVQKGDLVVVAAGVPTNVSGTTNMLKVQVVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-103 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-104 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-104 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-103 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_004635179.1 pyruvate kinase (pykA) VFG0479 Protein 3e-104 51