Gene Information

Name : vanH (SMB_G1568)
Accession : YP_004636210.1
Strain : Clostridium acetobutylicum DSM 1731
Genome accession: NC_015687
Putative virulence/resistance : Resistance
Product : lactate dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 1689266 - 1690246 bp
Length : 981 bp
Strand : +
Note : -

DNA sequence :
GTGAAAATTTTAGTATATAATCATAGAGCTGATGAAACTGAATATTTTCAAAAGTTTAAAGAAAAATACAATGTTGATTT
AATGCTTACAGACAAGACACCGACCATTGAAACTGCTGATTTTGCAAAAGGATTTGACTGCATAAGTATTATTACAACTC
CAATTAATGCAGCGCTTATTAAAAAGTTTAACGACGTTGGAGTTAAATTTATATCCACTAGAACTATAGGGTATGACCAC
ATAGATATTAAAAAAGCTAAAGAGCTCAGAATTGGTGTAGGAAACGTAACATATTCACCAAGAAGCGTAGCTGATTATAC
TGTAATGATGATTTTAATGGCAACAAGAAAAGTAAAAGCAATTATGCAGAATAGCTATGTTCAAGATTATTCTCTAGAAG
GTATTCAGGGAAAAGAATTACATAATTTAACCGTAGGAGTTATAGGAACAGGGAAGATTGGGAGAACAGTAATTAAAAAT
TTAAAGGGTTTTGAATGCAACATTATAGCCTATGATATCAATGAAAATGAAGAAGTTAAAGCCCATGCTAAATATGTGAA
ATTAGAAGAACTTTTAATGAGTAGTGATGTTATCACAGTGCATGTTCCAGGAGCGGAAGATAACTACCATCTAATAAATA
AAAATTCCATATCAAAAATGAAAGATGGGGTATTTATTATAAATACAGCAAGAGGGTCAATTATAAACACATATGATTTT
ATTGACGCTGTTGAAAAAGGGAAAATTGGTGGAGCAGCATTAGATGTAATAGAAAATGAAACAAATCTCTACTATAAAAA
TCTTAAAGGAGAAGTGTTAGGAAATAGAGAATTAGCTGTTTTAAAGTCTTATCCTAATGTGATTATTACACCTCATACAG
CATTCTATACAGATCAAGCAGTTAGCGATATGGTTGAGAATTCTATACTAAGTTGTATAGCTTTTTATGAGGGAAAAGAA
AATCCTTGGAAAGTGTTATAA

Protein sequence :
MKILVYNHRADETEYFQKFKEKYNVDLMLTDKTPTIETADFAKGFDCISIITTPINAALIKKFNDVGVKFISTRTIGYDH
IDIKKAKELRIGVGNVTYSPRSVADYTVMMILMATRKVKAIMQNSYVQDYSLEGIQGKELHNLTVGVIGTGKIGRTVIKN
LKGFECNIIAYDINENEEVKAHAKYVKLEELLMSSDVITVHVPGAEDNYHLINKNSISKMKDGVFIINTARGSIINTYDF
IDAVEKGKIGGAALDVIENETNLYYKNLKGEVLGNRELAVLKSYPNVIITPHTAFYTDQAVSDMVENSILSCIAFYEGKE
NPWKVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-65 45
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 5e-65 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vanH YP_004636210.1 lactate dehydrogenase AF155139.2.orf4.gene Protein 3e-65 45
vanH YP_004636210.1 lactate dehydrogenase NC_014475.1.orf2.gen Protein 3e-63 44
vanH YP_004636210.1 lactate dehydrogenase NC_005054.2598279.p0 Protein 3e-63 44
vanH YP_004636210.1 lactate dehydrogenase AF310956.2.orf4.gene Protein 7e-66 44
vanH YP_004636210.1 lactate dehydrogenase U35369.1.gene5.p01 Protein 1e-65 43
vanH YP_004636210.1 lactate dehydrogenase FJ349556.1.orf3.gene Protein 8e-61 43
vanH YP_004636210.1 lactate dehydrogenase AF130997.1.orf3.gene Protein 1e-58 42