Gene Information

Name : merA (OCA5_pOC16700650)
Accession : YP_004634380.1
Strain :
Genome accession: NC_015685
Putative virulence/resistance : Resistance
Product : mercuric reductase MerA
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 57947 - 59401 bp
Length : 1455 bp
Strand : +
Note : -

DNA sequence : 
ATGAAAGTTGAAGCCATGAATGACTGCTGCGCTTCGCCTGCGGGCAACGGCAATGACCAATACGATCTTGTCGTCGTCGG
CGCCGGATCGGCGGGCTTCTCGGCCGCAATCACCGCGGCGGGGCAGGGTGCGCAGGTCGCGCTCGTCGGGAACGGCACGA
TCGGCGGCACCTGCGTCAACATCGGCTGTGTGCCCTCGAAAACGCTGATCCGCGCTGCTGAGACCGTGCACCACGCCAAT
ATTGCATCAACCCGGTTTGACGGCATTGAAAGCAGGGCGCGCATGGTCGATTGGGCCGCACAGATCGCCCAGAAGGATGC
GCTGGTCGCGAGTCTCCGTCAGACGAAGTACGCCGACCTTCTTCCAGAATACAACAACGTCGCCTATCGTGAAGGCCAGG
CGCGGCTGGTCGCGGGAGGAATCGATGTGGGTGGTCAGCGCCTCGTATCGGATCGCATCATTATCGCGACCGGCGCCCGG
CCCGCACTGCCCGCCATTCCAGGCCTCGCGGAGGTTGTGCCTCTCGACAGTACGACCGCGTTGTCGCTGACGGAACTACC
GCGCTCCATGATTGTGCTGGGCGGTGGCTACGTCGGGGTCGAACTTGCACAGACCTTTGCTCGCGTCGGTGTCGCGGTGA
CGCTGGTCTTCCGCAGCCGCCTTTTGCCCGAGGCCGAGCCGGAGATCGGGCAAGCGCTCGCGGGCTATCTGGCCGATGAG
GGCATCACGATCGTGAGGGGCGTGACCTACGATGTTGTCCGCAAGACCGATGACGACGGCGTCGCGCTCGCGATCACCCG
GAATGGTAGTCCTGAGATATTGACCGCCGAGCGGATTCTTGTCGCTACGGGGCGCACCCCGAACACCGAAGGCCTCGGGC
TTTCTGAAGCGGGAGTCGTGCAGACGTCGTCCGGCGCGATCGTCGTCGACGACCGTATGCGTACCTCGAAGGCAGGCGTC
TATGCGGTTGGCGACGTGACGGGCAAGGACCAGTTCGTCTACATGGCGGCCTATGGTGCAAAGCTCGCGGCCAAGAATGC
GCTGAACAGCAACAGCTTGCGTTACGACAACACCGCCATGCCCGCCGTTGTCTTCACGGACCCTCAGGTGGCGAGCGTCG
GTTTGACCGAAGCGCAAGCGCGTGCTGCCGGGCACCCCGTGCGAACTTCAGTGCTCTCGCTCGATAACGTGCCGCGTGCG
CTCGCGGCCCGCGATACGCGGGGCCTGATCAAGCTTGTCGCGGATGGGGCAACCCGCAAGCTGCTGGGAGCGCATATTCT
CGCGCCGGAAGGCGCCGACAGCATCCAGACGGCGGCGCTCGCCATCCGCTGTGGGCTTTCGATCGACGATCTGTCGGAAA
TGATCTTCCCCTACCTGACCACCGTCGAGGGTTTGAAGCTTGCGGCGCAGACGTTTGACCGGGACGTGAAGAAACTCTCC
TGCTGCGCCGGGTAG

Protein sequence : 
MKVEAMNDCCASPAGNGNDQYDLVVVGAGSAGFSAAITAAGQGAQVALVGNGTIGGTCVNIGCVPSKTLIRAAETVHHAN
IASTRFDGIESRARMVDWAAQIAQKDALVASLRQTKYADLLPEYNNVAYREGQARLVAGGIDVGGQRLVSDRIIIATGAR
PALPAIPGLAEVVPLDSTTALSLTELPRSMIVLGGGYVGVELAQTFARVGVAVTLVFRSRLLPEAEPEIGQALAGYLADE
GITIVRGVTYDVVRKTDDDGVALAITRNGSPEILTAERILVATGRTPNTEGLGLSEAGVVQTSSGAIVVDDRMRTSKAGV
YAVGDVTGKDQFVYMAAYGAKLAAKNALNSNSLRYDNTAMPAVVFTDPQVASVGLTEAQARAAGHPVRTSVLSLDNVPRA
LAARDTRGLIKLVADGATRKLLGAHILAPEGADSIQTAALAIRCGLSIDDLSEMIFPYLTTVEGLKLAAQTFDRDVKKLS
CCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-89 47
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-89 47
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-76 47
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-78 47
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-78 47
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-78 47
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-76 46
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-76 46
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-76 46
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-75 46
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 2e-75 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-75 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_004634380.1 mercuric reductase MerA BAC0651 Protein 1e-89 47
merA YP_004634380.1 mercuric reductase MerA BAC0652 Protein 1e-77 47
merA YP_004634380.1 mercuric reductase MerA BAC0653 Protein 2e-77 46
merA YP_004634380.1 mercuric reductase MerA BAC0650 Protein 6e-73 43
merA YP_004634380.1 mercuric reductase MerA BAC0649 Protein 5e-75 43