Gene Information

Name : guaA (CULC22_00480)
Accession : YP_004629117.1
Strain : Corynebacterium ulcerans BR-AD22
Genome accession: NC_015683
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 515618 - 517192 bp
Length : 1575 bp
Strand : +
Note : GMP synthase, PP-ATPase domain/subunit

DNA sequence :
GTGACACAGCAAACTCCCCAAAAACATAATCCGGTACTAGTCGTCGACTTCGGCGCTCAGTATGCGCAGCTCATTGCCCG
GCGCGTCCGTGAAGCAAAGATCTATTCGGAAGTGGTTCCGCATACCGCGACCGTTGAAGAAATTAAAGCCAAAAATCCTG
CGGCGCTAGTCTTGTCGGGTGGCCCCTCGTCTGTGTATGAGACCGGGGCACCGTCTCTTGACCCAGCACTGCTGGAATTA
GGAATCCCTGTCTTCGGTATTTGCTATGGATTCCAGGCGATGACCCATGCACTTGGGGGAACTGTAGCCAACACAGGGAA
CCGCGAATACGGACGCACCGAACTGGTTGTTGAGGGCGGCGTACTGCATGAAGGCCTAGAAAAGACCCATAAAGTCTGGA
TGAGCCACGGCGATGCGGTGTCTCAAGCTCCGGAAGGATTCGTCGTTTCTGCCCACTCGGAGGGCGCTCCGGTGGCGGCG
TTTGAGTGCGTCGAAAAGCGCATGGCAGGCGTGCAGTATCACCCAGAGGTGCTGCACTCACCGCATGGTCAAGAGGTTCT
GGTTCGATTCCTCACAGAGATCGCAGGGTTGGAACAGAATTGGACTGCGGCAAATATCGCTGAAGAGCTTATCCAGGCGG
TTCGGGATCAGGTTGGTCCTGAGGGACGCGCGATTTGTGGTCTTTCCGGTGGCGTCGATTCTGCGGTGGCGGGAGCGTTG
GTACAGCGCGCTATTGGCGACCGTCTCACGTGTGTCTTTGTGGATCACGGTCTGCTGCGCGCTGGCGAGCGTGAGCAGGT
ACAGAAGGACTTTGTGGCGTCGACAGGCGCTAAGCTCGTGACAGTTGACGAGCGAGCTGCCTTCCTGAATAAGTTGGCTG
GTGTCACTGAGCCAGAGGCAAAGCGCAAAGCCATCGGGGCGGAATTTATCCGTTCTTTTGAGCGCGCTGTCGCCGGCGTG
TTGGAAAGCGCTCCGGGAGCGAGCGTAGATTTCCTCGTCCAAGGCACCTTGTACCCGGATGTTGTCGAATCTGGTGGTGG
CGCAGGCACCGCGAATATCAAGAGCCACCACAACGTTGGCGGGCTCCCTGATGATGTGGAGTTTAAGCTCGTTGAGCCGC
TGCGTCTGCTCTTCAAAGACGAAGTTCGTGCTGTTGGACGAGAGCTAGGACTGCCCGAGGAGATCGTGAACCGCCAGCCC
TTCCCAGGGCCAGGTCTGGGCATCCGCATTATCGGCGAGGTCACTGAGGATCGTCTAGAGACCTTGCGCGCCGCCGATCT
TATCGCCCGCACTGAGCTCACAGCCGCTGGCTTGGACGACCAGATCTGGCAGTGCCCTGTGGTGTTGCTTGCCGACGTCC
GCTCCGTGGGCGTTCAAGGCGATGGCCGCACGTACGGTCACCCGATTGTGCTGCGCCCGGTTTTCTCCGAAGACGCGATG
ACTGCGGACTGGACACGCTTGCCTTATGAGGTCTTGGAGAAGATCTCTACGCGCATCACCAACGAGGTGCCAGACGTCAA
CCGCGTGGTTCTCGACTGCACTTCCAAGCCCCCAGGAACCATCGAGTGGGAGTAA

Protein sequence :
MTQQTPQKHNPVLVVDFGAQYAQLIARRVREAKIYSEVVPHTATVEEIKAKNPAALVLSGGPSSVYETGAPSLDPALLEL
GIPVFGICYGFQAMTHALGGTVANTGNREYGRTELVVEGGVLHEGLEKTHKVWMSHGDAVSQAPEGFVVSAHSEGAPVAA
FECVEKRMAGVQYHPEVLHSPHGQEVLVRFLTEIAGLEQNWTAANIAEELIQAVRDQVGPEGRAICGLSGGVDSAVAGAL
VQRAIGDRLTCVFVDHGLLRAGEREQVQKDFVASTGAKLVTVDERAAFLNKLAGVTEPEAKRKAIGAEFIRSFERAVAGV
LESAPGASVDFLVQGTLYPDVVESGGGAGTANIKSHHNVGGLPDDVEFKLVEPLRLLFKDEVRAVGRELGLPEEIVNRQP
FPGPGLGIRIIGEVTEDRLETLRAADLIARTELTAAGLDDQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVFSEDAM
TADWTRLPYEVLEKISTRITNEVPDVNRVVLDCTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 93
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-129 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-129 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 51