Gene Information

Name : ureC (CULC22_02151)
Accession : YP_004630775.1
Strain : Corynebacterium ulcerans BR-AD22
Genome accession: NC_015683
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2351619 - 2353328 bp
Length : 1710 bp
Strand : -
Note : Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGTCTTTTGAAATGAGTCGGCGCCAGTACGCAGAACTGAACGGTCCGACCACTGGCGACGGAATCCGTTTGGCTGATAC
AGAGCTCATCGCCGTTGTCGAGAAAGATCTTACCCAGTACGGCGACGAGGTTTCCTTCGGCGGCGGAAAGGTTATCCGCG
ATGGCATGGGTCAAAACTCGCGCGTCGAGGCAGATCAGGTCCCAGACCTGGTTATCACGAACACCATTATCGTGGACTAC
ACCGGTATTTACTCTGCTGATATTGCTGTGAAAGACGGCAGGATCATGAAGATCGGTAAAGCCGGCAACCCCGATATTAT
GGACAACATCGACATCATCGTCGGTGTCGGAACTGAGGTTATCGGTGGCGAAGGCAAGATTGTCACCGCTGGTGCTATTG
ATACGCACATCCACTTCATTTCCCCAGAACAGGTGGAAGCAGCACTAGATAACGGCACGACCACCCTTATCGGTGGCGGA
ACAGGTCCAGTGGACTCTACCAATGCTACGACCGTTACCGCAGGTGCCGGCAACATCACCAAGATGATCGAGGCTTCTCG
CGACTTCTCCGTGAACGTCGGTTTCTTGGGCAAGGGCCACGCCTCCAACACCGAGCGTCTGCGTGAGCAGATTCGTGCAG
GTGCTATCGGTCTGAAGATCCACGAGGACTGGGGCGCTACCGCTAACACCATCGACAACGCACTGACCGTTGCTGATGAG
ATGGACATTCAGGTTGCTATCCACACCGATACCCTGAACGAGGGCGGCTTTGCTGATAACACCATTGCGGCTTTCAAAGA
CCGCGTTATTCACACCTTCCACACCGAAGGAGCTGGCGGCGGACACGCTCCGGACATCCTGAAGGTAGCTGGTCTTCCTA
ACGTTCTTCCGGCATCCACCAACCCAACTCTTCCGTTCACCGTGAACACGATGGATGAGCACCTTGACATGATCATGGTG
TGCCACCACCTCAACTCTGACCTCCCTGAGGACATTGCATTCGCTGATTCACGTATCCGTAAGGAAACCATTGCGGCGGA
AGACGTCCTGCACGATATGGGCGTTTTGGCAATCACCTCTTCTGACTCTCAGGCCATGGGCCGCGTCGGCGAGGTTGTCC
TGCGTACCTGGCAGGTTGCTCACCGTATGAAGCAGCAGCGTGGACCGCTTGAGGGCGATACCGCTACCAACGATAACGAG
CGCATCAAGCGTTACATTGCTAAGTACACCATCAACCCAGCTATTGCTTCCGGTGTTGCAGATACCATTGGTTCTGTTGA
AGAAGGCAAGCTAGCTGACCTGGTTGTTTGGGATCCTGCTTACTTCGGTGTGAAGCCAAGCATCGTGATCAAGTCCGGCA
TCATCGCTCGCTCCATCATGGGCGACGCTAACGCTTCGATCCCGACCCCACAGCCACGTACTATGCGTTACTCCTATGGC
GCTCGCGGTGCAGCTGCTGGTCGTACCTCGGTTACCTTCCTCCCCACGGCAGCTTTCGAGGCTGGCGTACCGGAGAAGCT
TGGTATTGATCGTAAGTTCGTTGAAGCAAAGAACATGCGCGAGATCTCCAAGGCTGATCTGAAGCACAACAATGCAACCC
CAGATATCAAGGTTGATCCAGAGACCTACGAGTTGACGGTTGACGGCGAGAAAGTCACTTCTGAGGCTGCTACAGAGCTG
CCGATGACTCAGCGTTACTTCCTGTTCTAG

Protein sequence :
MSFEMSRRQYAELNGPTTGDGIRLADTELIAVVEKDLTQYGDEVSFGGGKVIRDGMGQNSRVEADQVPDLVITNTIIVDY
TGIYSADIAVKDGRIMKIGKAGNPDIMDNIDIIVGVGTEVIGGEGKIVTAGAIDTHIHFISPEQVEAALDNGTTTLIGGG
TGPVDSTNATTVTAGAGNITKMIEASRDFSVNVGFLGKGHASNTERLREQIRAGAIGLKIHEDWGATANTIDNALTVADE
MDIQVAIHTDTLNEGGFADNTIAAFKDRVIHTFHTEGAGGGHAPDILKVAGLPNVLPASTNPTLPFTVNTMDEHLDMIMV
CHHLNSDLPEDIAFADSRIRKETIAAEDVLHDMGVLAITSSDSQAMGRVGEVVLRTWQVAHRMKQQRGPLEGDTATNDNE
RIKRYIAKYTINPAIASGVADTIGSVEEGKLADLVVWDPAYFGVKPSIVIKSGIIARSIMGDANASIPTPQPRTMRYSYG
ARGAAAGRTSVTFLPTAAFEAGVPEKLGIDRKFVEAKNMREISKADLKHNNATPDIKVDPETYELTVDGEKVTSEAATEL
PMTQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 0.0 98
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 98
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 98
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 98
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-159 63
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-159 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004630775.1 urease subunit alpha VFG0270 Protein 1e-139 58