Gene Information

Name : aldA (CULC22_02123)
Accession : YP_004630747.1
Strain : Corynebacterium ulcerans BR-AD22
Genome accession: NC_015683
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2316115 - 2317635 bp
Length : 1521 bp
Strand : -
Note : NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACGATTTATGCTAATCCGGGTACTGAAGGCGCAGTCGCTAACTATAAGAAGCGCTACGACAACTACATTGGCGGTCA
ATGGGTACCGCCTGTAGACGGCGAATATCTAGACAATGTCACTCCGGTTACTGGCGAGGTATTCTGCCAGGTTGCCCGTG
GTAAAGCGGCAGATGTTGAGAAGGCTCTCGACGCTGCGCATGCTGCGGCGGAGGCGTGGGGTAAGACCTCGCCGGCGGAG
CGTGCCCTGGTATTGCACCGGATTGCGGACCGTATGGAAGAACATCTGGAAGAAATTGCCGTTGCGGAGACCTGGGAGAA
TGGCAAGGCTGTACGTGAGACGCTAGCGGCTGATATTCCCCTGGCTATTGACCACTTCCGCTATTTTGCGGGTGCTATTC
GGGCCCAGGAGTCGCGAACGTCGCAGATTGATCACAATACGGTTGCTTATCACTTCCATGAGCCCATTGGAGTGGTGGGG
CAAATCATTCCATGGAACTTCCCATTGTTGATGGCCGCCTGGAAGATTGCTCCTGCTTTAGCTGCTGGCAATGCGATCGT
TCTTAAGCCTGCCGAGCAGACCCCAGCCTCGATTCTGTATTGGATCGATATTGTGGGAGATCTGATTCCAGATGGCGTTC
TTAACATTGTGAACGGTTTGGGGGAGGAAGCTGGCGTTGCGCTTTCTAGCTCTACTCGCATCGGCAAGATTGCCTTCACT
GGCTCGACGCAGGTGGGCAAGTTAATCAACAAGGCTGCCGCGGACAAGATCATTCCAGTCACTCTGGAACTGGGCGGAAA
GTCGCCATCGATTTTCTTTGGTGACGTTATGGATTACGAAGACCCCTTCCGGGACAAGTGTATCGAGGGACTTGCAATGT
TTGCCCTGAATCAGGGTGAGGTGTGTACCTGTCCTTCGCGTGCGCTTGTTCACGAGTCCATTGCAGAAGAATTCCTGGCG
TTAGGTGTGGAGCGAGTGCGCAAGATCAAGCTCGGTAATCCTTTGGATACTGAGACCATGATGGGTGCCCAGGCCTCCAT
GGAGCAGATGGATAAGATTTCTGGATACTTGGACATTGGCCCGAAGGAAGGGGCCGAGGTACTTACTGGTGGTCATGTCA
ACCGTATTGATGGTTTGGAGAATGGCTATTACATTGAGCCGACCATCTTCAAAGGGACTAATGATATGCGTATCTTCCAG
GAAGAAATCTTCGGTCCAGTGCTCTCGGTTGCTACCTTTAGTGACTTTGATGAGGCTATTCGGATTGCAAATGACACCAA
TTATGGCCTTGGTGCCGGTGTATGGACTCGTCATCAAAACACCGCATATCGCGCTGGACGTGCTATCCAGGCGGGTCGTG
TGTGGGTGAATCAGTATCACAATTACCCAGCTCATGCGGCCTTTGGCGGGTATAAGGAATCGGGAATTGGGCGCGAAAAC
CACCTGATGATGCTGGATCACTACCAGCAGACCAAGAATCTGCTCGTTTCTTATGATGAAAACCCTACGGGCTTATTTTA
G

Protein sequence :
MTIYANPGTEGAVANYKKRYDNYIGGQWVPPVDGEYLDNVTPVTGEVFCQVARGKAADVEKALDAAHAAAEAWGKTSPAE
RALVLHRIADRMEEHLEEIAVAETWENGKAVRETLAADIPLAIDHFRYFAGAIRAQESRTSQIDHNTVAYHFHEPIGVVG
QIIPWNFPLLMAAWKIAPALAAGNAIVLKPAEQTPASILYWIDIVGDLIPDGVLNIVNGLGEEAGVALSSSTRIGKIAFT
GSTQVGKLINKAAADKIIPVTLELGGKSPSIFFGDVMDYEDPFRDKCIEGLAMFALNQGEVCTCPSRALVHESIAEEFLA
LGVERVRKIKLGNPLDTETMMGAQASMEQMDKISGYLDIGPKEGAEVLTGGHVNRIDGLENGYYIEPTIFKGTNDMRIFQ
EEIFGPVLSVATFSDFDEAIRIANDTNYGLGAGVWTRHQNTAYRAGRAIQAGRVWVNQYHNYPAHAAFGGYKESGIGREN
HLMMLDHYQQTKNLLVSYDENPTGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-141 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-150 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-150 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-150 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-150 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_004630747.1 aldehyde dehydrogenase VFG0082 Protein 2e-141 64