Gene Information

Name : clpB1 (CULC22_02108)
Accession : YP_004630732.1
Strain : Corynebacterium ulcerans BR-AD22
Genome accession: NC_015683
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.21.92
Position : 2296320 - 2298869 bp
Length : 2550 bp
Strand : -
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATTCATTCAATCCAACAACTAAAACGCAAGAGGCTTTGCAGGTTGCGCTGCAGCAGGCCTCGTCGCTGGGCAATCC
GGATATTCGCCCAGCTCATTTACTTGCAGCGATCTTAGGTCAGGAAGATGGCATTGCGGTGCCGGTCTTGCGTGCTACGG
GCGTGGACCCGCAGGTGGTGGCGCAGGAGGCCAACGCGCTTGTGGCAGGGTATCCCAAGGCTGAGGGTTCTGGGATGGCA
AATCCCAACTTTAACCGCGAGGCTTTGAACGCGCTGACCGCTGCGCAGGAGCTGGCTGGCGAATTAGGCGATGAGTATGT
GTCCACCGAGGTGCTGCTCGCTGCGATTGCTCGGGGAAAGTCCGATGCTGCGGAATTACTGACTAAGCGAGGCGCTACCT
ATGACGTTATTAAAGGTGTGTTCCCCTCTGTGAGAGGAAGCAAGAAGGTGACTAGCCAAGACCCCGAGGGGCAGTTCCAG
GCTTTGGAGAAATATTCCACTGACCTTACGGCTCGTGCACGCGAGGGGAAGATCGACCCTGTTATTGGGCGTGACTCGGA
GATCCGCCGTGTGGTTCAGGTGTTGAGTCGCCGCACCAAGAATAATCCGGTTCTTATTGGTGAGCCGGGCGTGGGTAAGA
CCGCGATTGTAGAAGGTTTGGCTCGCCGGATCGTCGCCGGCGACGTGCCGGAATCTCTGAAGGGGAAGACCCTGATTAGC
CTTGACCTTGGCTCGATGGTCGCTGGTGCTAAGTACCGTGGCGAGTTTGAGGAGCGCCTCAAGGCTGTGCTTGATGAGAT
CAAGGCAGCAGAAGGTGAGGTCATTACCTTTATTGATGAGCTGCACACCATCGTTGGTGCGGGCGCTACCGGGGATTCCG
CTATGGATGCCGGCAACATGATTAAGCCGCTGCTGGCTCGTGGCGAGCTGCGCTTGGTGGGTGCCACCACCCTCGATGAG
TATCGCAAGTACATCGAGAAGGATGCTGCTTTGGAGCGCCGTTTCCAGCAGGTCTTTGTCGGCGAGCCATCTGTGGAGGA
CGCCATCGGTATCCTGCGCGGACTCAAAGAGCGCTATGAGGTGCATCATGGCGTGCGTATTCAAGATTCTGCATTGGTTG
CTGCGGCGACTCTTTCGGATCGCTACATCACGTCGCGTTTCTTGCCAGATAAGGCGATTGACCTGGTCGATGAGGCCGCT
AGCCGGCTGCGCATGGAGATCGATTCTTCCCCGCAGGAGATCGACGAGCTGGAGCGCATCGTGCGGCGTTTGGAGATTGA
AGAGGTCGCGCTGGGCAAAGAGACGGATGTGGCGTCTCAGCAGCGCTTGGAGAAGTTGCGCCAGGAGCTTGCCGACGAAC
GCGAGAAGCTCGGTGAGCTCAAAGCCCGCTGGAACAATGAGAAATCTGCAATAGATAAGGTGCGCGAGGCCAAGGAAGAA
TTGGAACACCTGCGTTCTGAGTCCGAGATCGCTGAGCGCGAAGGCGATTACGGCAAGGTAGCTGAGCTGCGCTATGGCCG
AATCCCGGAGTTGGAAAAGCAGGTGGCTGAGGCTGAGTCTCATACCACTGACACCACGATGCTTTCGGAGGAAGTCACCC
CGGACACTATCGCGGACGTTGTCTCTGCATGGACTGGTATTCCCGCAGGCAAGATGCTTCAGGGCGAGACTGAGAAGCTT
CTACACATGGAATCCGAGCTGGGTAACCGGGTAGTGGGCCAGCTAGAAGCCGTGGAGGCGGTATCTGATGCGGTGCGTCG
TGCGCGCGCTGGTGTGGCTGATCCGAATCGTCCGACTGGTTCGTTCCTCTTCCTCGGCCCTACAGGTGTGGGTAAGACTG
AGCTGGCCAAAGCCTTGGCTGAGTTCATGTTTGATGATGAACGTGCGATGGTACGCATTGATATGTCTGAGTACGGGGAG
AAGCACTCCGTGGCTCGGCTGGTTGGTGCCCCTCCCGGATATGTTGGTTACGATCAGGGCGGCCAGCTCACCGAGGCCGT
GCGCCGGCGTCCTTACACAGTAGTGCTTTTCGACGAAGTGGAGAAAGCTCACTCCGACGTCTTTGACATCCTGCTGCAGG
TGCTCGACGAGGGTCGGCTTACCGACGGCCAAGGCCGTACCGTCGACTTCCGAAACACCGTCCTCATCCTCACCTCCAAC
CTGGGAGCCGGTGGCACCCGCGAGCAGATGATGGATGCCGTCAAGCGGGCCTTTAAACCAGAATTTGTTAACCGCTTGGA
TGACGTAGTGATTTTTGATCCACTCTCAGAAGAGCAACTGACCTACATCGTGGACATTCAGATCGCGCAGCTGGCAGACC
GTCTTTCGGCGCGCCGCCTGACTCTGAATGTCTCGGATGCCGCCAAGCTGTGGCTGGCTGAACGCGGTTACGAGCCGGCT
TATGGTGCACGACCATTACGCCGCCTGATCCAGCAGGCGATTGGCGACCAGCTAGCTAAGAAGCTGCTGGCAGGTGAGAT
CCGCGACGGCGGTACCGTGCACGTGGATGTGGCCGATGGTGGCGGGGCTTTGGAACTGGCGAAGGGCTAA

Protein sequence :
MNSFNPTTKTQEALQVALQQASSLGNPDIRPAHLLAAILGQEDGIAVPVLRATGVDPQVVAQEANALVAGYPKAEGSGMA
NPNFNREALNALTAAQELAGELGDEYVSTEVLLAAIARGKSDAAELLTKRGATYDVIKGVFPSVRGSKKVTSQDPEGQFQ
ALEKYSTDLTARAREGKIDPVIGRDSEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKGKTLIS
LDLGSMVAGAKYRGEFEERLKAVLDEIKAAEGEVITFIDELHTIVGAGATGDSAMDAGNMIKPLLARGELRLVGATTLDE
YRKYIEKDAALERRFQQVFVGEPSVEDAIGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPQEIDELERIVRRLEIEEVALGKETDVASQQRLEKLRQELADEREKLGELKARWNNEKSAIDKVREAKEE
LEHLRSESEIAEREGDYGKVAELRYGRIPELEKQVAEAESHTTDTTMLSEEVTPDTIADVVSAWTGIPAGKMLQGETEKL
LHMESELGNRVVGQLEAVEAVSDAVRRARAGVADPNRPTGSFLFLGPTGVGKTELAKALAEFMFDDERAMVRIDMSEYGE
KHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVVLFDEVEKAHSDVFDILLQVLDEGRLTDGQGRTVDFRNTVLILTSN
LGAGGTREQMMDAVKRAFKPEFVNRLDDVVIFDPLSEEQLTYIVDIQIAQLADRLSARRLTLNVSDAAKLWLAERGYEPA
YGARPLRRLIQQAIGDQLAKKLLAGEIRDGGTVHVDVADGGGALELAKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-100 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-100 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB1 YP_004630732.1 ATP-dependent Clp protease ATP-binding subunit VFG2076 Protein 6e-110 41